Journal of Composites Science,
Год журнала:
2024,
Номер
8(2), С. 46 - 46
Опубликована: Янв. 26, 2024
Wound
management
heavily
relies
on
the
vital
contribution
of
wound
dressings,
emphasizing
significance
finding
an
ideal
dressing
that
can
fulfill
intricate
requirements
healing
process
with
multiple
functions.
A
promising
strategy
is
combining
several
materials
and
therapies
to
create
multifunctional
dressings.
Nanocomposite
hydrogel
dressings
based
nanomaterials,
advantages
nanomaterials
hydrogels
in
treatment,
significantly
improve
their
respective
performance
compensate
for
shortcomings.
variety
nanocomposite
diverse
structures
synergistic
functions
have
been
developed
recent
years,
achieving
results
applications.
In
this
review,
functions,
advantages,
limitations
as
are
first
discussed.
Additionally,
application
inorganic
also
elaborated
on.
Furthermore,
we
focused
summarizing
analyzing
healing,
which
contain
various
including
metals,
metal
oxides,
sulfides,
carbon-based
silicon-based
nanoparticles.
Finally,
prospects
envisaged,
providing
insights
further
research
management.
Advanced Functional Materials,
Год журнала:
2024,
Номер
34(38)
Опубликована: Апрель 27, 2024
Abstract
Antibacterial
photodynamic
therapy
(aPDT)
and
antibacterial
sonodynamic
(aSDT)
utilize
sensitizers
(photosensitizers/sonosensitizers)
to
produce
reactive
oxygen
species
(ROS)
for
treatment
under
the
stimulation
of
light/ultrasound,
which
have
characteristics
broad‐spectrum
properties,
low
drug‐resistance,
effective
targeting
infected
tissues.
Nanomaterials
in
aPDT/aSDT
are
primarily
used
as
nano‐sensitizers
or
nano‐carriers
sensitizers.
They
enhance
stability
permeability
sensitizers,
improve
strengthen
photodynamic/sonodynamic
properties
(modification
absorption
efficiency
light/ultrasonic
response
stress
by
modulation
nanoparticle
shape,
size,
structure).
Also,
they
modifiability
(controlling
release
rate
time
sensitizer
needed
optimize
therapeutic
effect),
programmability
multifunctionality
(flexible
application
nanotechnology
designing
with
multiple
functions,
such
drug
delivery,
targeted
therapy,
monitoring),
expand
possibilities
combination
therapies
(the
can
be
loaded
other
agents,
enabling
therapies).
expected
further
promote
development
achieve
improved
effects.
This
review
summarizes
progress
nanomaterials
recent
years
based
on
current
strategies
provide
a
theoretical
reference
aPDT/aSDT.
Abstract
In
recent
years,
there
has
been
growing
interest
in
developing
innovative
materials
and
therapeutic
strategies
to
enhance
wound
healing
outcomes,
especially
for
chronic
wounds
antimicrobial
resistance.
Metal–organic
frameworks
(MOFs)
represent
a
promising
class
of
next‐generation
dressings.
Their
high
surface
area,
pore
structures,
stimuli‐responsiveness,
antibacterial
properties,
biocompatibility,
potential
combination
therapies
make
them
suitable
complex
care
challenges.
MOF‐based
composites
promote
cell
proliferation,
angiogenesis,
matrix
synthesis,
acting
as
carriers
bioactive
molecules
promoting
tissue
regeneration.
They
also
have
stimuli‐responsivity,
enabling
photothermal
skin
cancer
infections.
Herein,
critical
analysis
the
current
state
research
on
MOFs
dressings
is
provided,
offering
valuable
insights
into
applications,
challenges,
future
directions
this
field.
This
literature
review
targeted
multifunctionality
nature
wound‐disease
therapy
from
different
aspects
discussed
most
advancements
made
context,
reader
will
find
how
contributed
field
yield
more
effective,
functional,
they
lead
next
generation
biomaterials
