Recent advances in the development and analytical applications of oxidase-like nanozymes

TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 166, С. 117220 - 117220

Опубликована: Авг. 3, 2023

Язык: Английский

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Breaking the pH Limitation of Nanozymes: Mechanisms, Methods, and Applications

Advanced Materials, Год журнала: 2024, Номер 36(31)

Опубликована: Апрель 14, 2024

Although nanozymes have drawn great attention over the past decade, activities of peroxidase-like, oxidase-like, and catalase-like are often pH dependent with elusive mechanism, which largely restricts their application. Therefore, a systematical discussion on pH-related catalytic mechanisms together methods to overcome this limitation is in need. In review, various exhibiting pH-dependent collected root causes for dependence comprehensively analyzed. Subsequently, regulatory concepts including environment reconstruction direct activity improvement break restriction summarized. Moreover, applications pH-independent sensing, disease therapy, pollutant degradation overviewed. Finally, current challenges future opportunities development suggested. It anticipated that review will promote further design broaden application range higher efficiency.

Язык: Английский

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Nanozymes: powerful catalytic materials for environmental pollutant detection and degradation

Environmental Science Nano, Год журнала: 2024, Номер 11(3), С. 766 - 796

Опубликована: Янв. 1, 2024

Here we made a critical review on nanozyme-involved detection and degradation of environmental pollutants, the research progress achieved in last five years was emphatically concluded.

Язык: Английский

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Oxidase mimicking nanozyme: Classification, catalytic mechanisms and sensing applications

Coordination Chemistry Reviews, Год журнала: 2024, Номер 520, С. 216166 - 216166

Опубликована: Авг. 22, 2024

Язык: Английский

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Applications of mild-condition synthesized metal complexes with enzyme-like activity in the colorimetric and fluorescence analysis

Coordination Chemistry Reviews, Год журнала: 2024, Номер 508, С. 215761 - 215761

Опубликована: Март 12, 2024

Язык: Английский

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Recent Advances in Optical Sensing for Tetracycline Antibiotics

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 178, С. 117839 - 117839

Опубликована: Июль 3, 2024

Язык: Английский

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Nanozyme‐Enabled Biomedical Diagnosis: Advances, Trends, and Challenges

Advanced Healthcare Materials, Год журнала: 2024, Номер unknown

Опубликована: Авг. 13, 2024

Abstract As nanoscale materials with the function of catalyzing substrates through enzymatic kinetics, nanozymes are regarded as potential alternatives to natural enzymes. Compared protein‐based enzymes, exhibit attractive characteristics low preparation cost, robust activity, flexible performance adjustment, and versatile functionalization. These advantages endow them wide use from biochemical sensing environmental remediation medical theranostics. Especially in biomedical diagnosis, feature catalytic signal amplification provided by makes emerging labels for detection biomarkers diseases, rapid developments observed recent years. To provide a comprehensive overview progress made this dynamic field, here an diagnosis enabled is provided. This review first summarizes synthesis nanozyme then discusses main strategies applied enhance their activity specificity. Subsequently, representative utilization combined biological elements disease reviewed, including related metabolic, cardiovascular, nervous, digestive diseases well cancers. Finally, some development trends nanozyme‐enabled highlighted, corresponding challenges also pointed out, aiming inspire future efforts further advance promising field.

Язык: Английский

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Nanozyme-Based Remodeling of Disease Microenvironments for Disease Prevention and Treatment: A Review

ACS Applied Nano Materials, Год журнала: 2023, Номер 6(15), С. 13792 - 13823

Опубликована: Июль 3, 2023

Nanomaterials that can mimic the activity of various enzymes have been studied extensively in biomedical field recent years. Nanozymes offer better stability and economic value comparison to natural enzymes. Additionally, nanozymes characteristics nanomaterials, such as photothermal properties designability, therefore considerable potential. The cellular microenvironment provides basis for maintaining normal cell growth function. Increasing evidence shows imbalances homeostasis constitute a major factor development many diseases. received attention years regulators microenvironment. In this Review, research on use remodel disease is discussed. First, definition, classification, enzyme-like activities are introduced; several microenvironments summarized including tumor, inflammatory, trauma microenvironments. role main strategies constructing intelligent responsive nanozyme systems specific applications remodeling diseased highlighted. Finally, therapeutic prospected. Nanozyme expected become strategy or an adjunct prevention treatment related

Язык: Английский

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Introducing molecular imprinting onto nanozymes: toward selective catalytic analysis

Analytical and Bioanalytical Chemistry, Год журнала: 2024, Номер 416(27), С. 5859 - 5870

Опубликована: Фев. 3, 2024

Язык: Английский

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A dual-mode optical sensor for sensitive detection of saxitoxin in shellfish based on three-in-one functional nanozymes

Journal of Food Composition and Analysis, Год журнала: 2024, Номер 130, С. 106190 - 106190

Опубликована: Март 21, 2024

Язык: Английский

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