Chemical Communications,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 27, 2024
A
covalent
organic
framework-based
multifunctional
nanomedicine,
CuO2@COF-SNO,
which
can
produce
reactive
oxygen
and
nitrogen
species
(ROS/RNS)
to
enhance
chemodynamic
therapy
of
tumors.
Current Pharmaceutical Design,
Год журнала:
2024,
Номер
30(35), С. 2801 - 2812
Опубликована: Авг. 7, 2024
As
cancer
therapy
progresses,
challenges
remain
due
to
the
inherent
drawbacks
of
conventional
treatments
such
as
chemotherapy,
gene
therapy,
radiation
and
surgical
removal.
Moreover,
their
associated
side
effects,
affect
both
cancerous
normal
cells,
making
photodynamic
(PDT)
an
attractive
alternative.
RSC Advances,
Год журнала:
2025,
Номер
15(5), С. 3098 - 3109
Опубликована: Янв. 1, 2025
Tumor
hypoxia
still
severely
limits
the
antitumor
efficiency.
Herein,
a
free-radical
initiator-based
carrier-free
smart
nanobomb
with
oxygen-independent
trimodal
therapeutic
effects
for
targeted
therapy
of
hypoxic
breast
tumor
at
low
dose.
Cancer
remains
a
global
health
challenge,
driving
the
need
for
advanced
treatments.
While
transition
metal
dichalcogenides
(TMDs)
show
promise
in
cancer
therapy,
their
stability
and
efficacy
require
improvement.
This
study
explores
TMD-based
composites
as
solution
to
enhance
therapeutic
potential.
review
begins
by
providing
an
overview
of
TMDs
emphasizing
preparation
techniques
fundamental
properties.
The
focus
is
then
shifted
categorizing
based
on
constituent
materials,
delving
into
various
types,
such
TMD-organic,
TMD-carbon,
TMD-metal
chalcogenide,
TMD-metal,
TMD-oxide
composites,
well
more
complex
ternary
multinary
systems.
We
further
explore
key
fabrication
strategies,
including
hydrothermal/solvothermal
methods
surface
deposition/coating
techniques.
Subsequently,
applications
treatment,
chemotherapy,
photothermal
phototherapy,
integrated
combination
therapies.
Finally,
critical
challenges
field
perspectives
potential
directions
future
research
are
presented.
Abstract
The
methodology
of
nanoarchitectonics
is
to
construct
functional
materials
using
nanounits
such
as
atoms,
molecules,
and
nanoobjects,
just
like
architecting
buildings.
Nanoarchitectonics
pursues
the
ultimate
concept
science
through
integration
related
fields.
In
this
review
paper,
under
title
interface‐interactive
nanoarchitectonics,
several
examples
structure
fabrication
function
development
at
interfaces
will
be
discussed,
highlighting
importance
with
nanoscale
considerations.
Two
sections
provide
some
solid
liquid
surfaces.
interfacial
environments,
molecular
structures
can
precisely
observed
analyzed
theoretical
calculations.
Solid
surfaces
are
a
prime
site
for
level.
has
potential
pave
way
cutting‐edge
functionality
based
on
advanced
observation
analysis.
Liquid
more
kinetic
dynamic
than
interfaces,
their
high
fluidity
offers
many
possibilities
fabrications
by
nanoarchitectonics.
latter
feature
advantages
in
terms
freedom
interaction
diversity
components,
therefore,
may
suitable
environments
functionalities.
final
section
then
discusses
what
needed
future
material
creation
Molecules,
Год журнала:
2024,
Номер
29(13), С. 3168 - 3168
Опубликована: Июль 3, 2024
Nanoscale
science
is
becoming
increasingly
important
and
prominent,
further
development
will
necessitate
integration
with
other
material
chemistries.
In
words,
it
involves
the
construction
of
a
methodology
to
build
up
materials
based
on
nanoscale
knowledge.
This
also
beginning
concept
post-nanotechnology.
role
belongs
nanoarchitectonics,
which
has
been
rapidly
developing
in
recent
years.
However,
scope
application
nanoarchitectonics
wide,
somewhat
difficult
compile
everything.
Therefore,
this
review
article
introduce
concepts
liquid
interface,
are
keywords
for
organization
functional
systems
biological
systems.
The
target
interfaces
liquid-liquid
liquid-solid
so
on.
Recent
examples
summarized
under
categories
molecular
assembly,
metal-organic
framework
covalent
organic
framework,
living
cell.
addition,
latest
research
interfacial
semiconductor
film
discussed.
final
conclusive
section
summarizes
these
features
discusses
necessary
components
nanoarchitectonics.
Current Topics in Medicinal Chemistry,
Год журнала:
2024,
Номер
24(17), С. 1490 - 1503
Опубликована: Май 6, 2024
Abstract:
Nutraceuticals
are
products
that
provide
both
nutritional
and
therapeutic
benefits.
These
compounds
can
slow
the
aging
process
physiological
effects
shielding
individuals
from
acute
chronic
diseases.
People's
interests
have
shifted
allopathic
to
Ayurvedic
nutraceuticals
in
recent
years.
often
common
dietary
supplements
drawn
customers
worldwide
because
of
their
high
safety
lack
adverse
when
used
for
a
long
time.
Although
conventional
dosage
forms,
including
pills,
tablets,
semi-solids,
still
available,
they
nevertheless
poorer
bioavailability,
less
stability,
effectiveness
targeted
delivery
bioactives.
The
use
effective
nanocomplex
systems
as
nano-antioxidants
using
nanotechnology
has
become
promising
field.
Among
its
many
uses,
is
mostly
create
foods
more
bioavailable,
toxic,
sustainable.
Additionally,
it
been
emphasized
how
precisely
nano-pharmaceuticals
oxidative
stress
produce
desired
effects.
improvements
show
improved
antioxidant
target
region,
reduced
leakage,
increased
targeting
precision.
outcomes
demonstrated
stress-related
illnesses
be
effectively
treated
by
lowering
ROS
levels
with
nanonutraceuticals.
major
ideas
uses
nano-nutraceuticals
health
outlined
this
review,
an
emphasis
on
reducing
stress.