Potential Biosafety of Mxenes: Stability, Biodegradability, Toxicity and Biocompatibility DOI
Tetiana R. Dmytriv, Volodymyr I. Lushchak

The Chemical Record, Год журнала: 2024, Номер 24(4)

Опубликована: Фев. 22, 2024

Abstract MXenes are two‐dimensional nanomaterials with unique properties that widely used in various fields of research, mostly the field energy. Fewer publications devoted to MXene application biomedicine and question is: safe for use biological systems? The sharp edges provide structure ”nanoknives“ which cause damage direct physical contact cells. This is effectively antibacterial research. However, on other hand, most studies cultured cells rodents report they do not obvious signs cytotoxicity fully biocompatible. aim our review was consider whether can really be considered non‐toxic Often last two concepts confused. We first reviewed aspects such as stability biodegradation MXenes, then analyzed mechanisms toxicity their consequences bacteria, cells, rodents, subsequent conclusions regarding biocompatibility.

Язык: Английский

Nb2CTx-Based MXenes Most Recent Developments: From Principles to New Applications DOI Creative Commons
Tholkappiyan Ramachandran, Abdel‐Hamid I. Mourad, Mostafa S. A. ElSayed

и другие.

Energies, Год журнала: 2023, Номер 16(8), С. 3520 - 3520

Опубликована: Апрель 18, 2023

MXenes are progressively evolving two-dimensional (2D) materials with an expanding wide range of applications in the field energy storage. They rank among best electrode for cutting-edge storage systems. Energy device performance is greatly enhanced by and their composite materials. As technology has improved over last several decades, demand high-capacity devices that versatile, sturdy, have cheap production costs increased. MXene, which based on Nb2CTx, most current material to emerge applications. Nb2CTx MXene now sought-after 2D family due its flexibility, high conductivity, superior electrochemical nature, hydrophilicity, tunable surface functional groups, great mechanical properties, layered structure. Examples include gas biosensors, water splitting, purification, antimicrobial coatings, electromagnetic interference shielding, transparent electrical conductors. Because distinctive properties scientists working further theoretical experimental enhancements. The objective this work deliver outline breakthroughs construction robust, flexible, highly effective powered supercapacitors. Deep research been conducted structure as well different synthesis techniques properties. emphasis also placed how various aspects, such architecture design, electrolyte composition, so on, influence charge efficiency MXene-based This article discusses recent advancements composite-based

Язык: Английский

Процитировано

52

Multifunctional MXene-Based Bioactive Materials for Integrated Regeneration Therapy DOI
Junping Ma,

Long Zhang,

Bo Lei

и другие.

ACS Nano, Год журнала: 2023, Номер 17(20), С. 19526 - 19549

Опубликована: Окт. 7, 2023

The reconstruction engineering of tissue defects accompanied by major diseases including cancer, infection, and inflammation is one the important challenges in clinical medicine. development innovative strategies such as multifunctional bioactive materials presents a great potential to overcome challenge disease-impaired regeneration. As representative two-dimensional nanomaterials, MXenes have shown physicochemical properties been diffusely studied multimodal nanoplatforms field biomedicine. This review summarized recent advances integrated regeneration-therapy applications MXene-based biomaterials, regeneration-tumor therapy, regeneration-infection regeneration-inflammation therapy. recognized good candidates for promoting regeneration treating through photothermal regulating cell behavior, drug gene delivery. current future perspectives biomaterials are also discussed well this review. In summary, promising disease treatment due their favorable functions. However, there still many obstacles that must be addressed understanding mechanism, ensuring long-term biosafety, improving targeting therapy capacity.

Язык: Английский

Процитировано

46

Engineered Probiotic Bio‐heterojunction with Robust Antibiofilm Modality via “Eating” Extracellular Polymeric Substances for Wound Regeneration DOI

Miao Qin,

Xiumei Zhang, Haiyang Ding

и другие.

Advanced Materials, Год журнала: 2024, Номер 36(35)

Опубликована: Июнь 25, 2024

The compact three-dimensional (3D) structure of extracellular polymeric substances (EPS) within biofilms significantly hinders the penetration antimicrobial agents, making biofilm eradication challenging and resulting in persistent biofilm-associated infections. To address this challenge, a solution is proposed: probiotic bio-heterojunction (P-bioHJ) combining Lactobacillus rhamnosus with MXene (Ti

Язык: Английский

Процитировано

29

MXene: A wonderful nanomaterial in antibacterial DOI Creative Commons

Surong Ye,

Huichao Zhang,

Huiyan Lai

и другие.

Frontiers in Bioengineering and Biotechnology, Год журнала: 2024, Номер 12

Опубликована: Фев. 1, 2024

Increasing bacterial infections and growing resistance to available drugs pose a serious threat human health the environment. Although antibiotics are crucial in fighting infections, their excessive use not only weakens our immune system but also contributes resistance. These negative effects have caused doctors be troubled by clinical application of antibiotics. Facing this challenge, it is urgent explore new antibacterial strategy. MXene has been extensively reported tumor therapy biosensors due its wonderful performance. Due large specific surface area, remarkable chemical stability, hydrophilicity, wide interlayer spacing, excellent adsorption reduction ability, shown potential for biopharmaceutical applications. However, there few antimicrobial evaluations on MXene. The current mechanisms mainly include physical damage, induced oxidative stress, photothermal photodynamic therapy. In paper, we reviewed MXene-based composites discussed guide further research field.

Язык: Английский

Процитировано

27

Potential Biosafety of Mxenes: Stability, Biodegradability, Toxicity and Biocompatibility DOI
Tetiana R. Dmytriv, Volodymyr I. Lushchak

The Chemical Record, Год журнала: 2024, Номер 24(4)

Опубликована: Фев. 22, 2024

Abstract MXenes are two‐dimensional nanomaterials with unique properties that widely used in various fields of research, mostly the field energy. Fewer publications devoted to MXene application biomedicine and question is: safe for use biological systems? The sharp edges provide structure ”nanoknives“ which cause damage direct physical contact cells. This is effectively antibacterial research. However, on other hand, most studies cultured cells rodents report they do not obvious signs cytotoxicity fully biocompatible. aim our review was consider whether can really be considered non‐toxic Often last two concepts confused. We first reviewed aspects such as stability biodegradation MXenes, then analyzed mechanisms toxicity their consequences bacteria, cells, rodents, subsequent conclusions regarding biocompatibility.

Язык: Английский

Процитировано

27