Materials Today Bio,
Год журнала:
2024,
Номер
29, С. 101323 - 101323
Опубликована: Ноя. 8, 2024
Intervertebral
disc
degeneration
(IDD)
is
a
common
degenerative
disease
of
the
spine
that
has
significant
impact
on
both
society
and
human
health.
Many
studies
have
confirmed
there
close
relationship
between
IDD
senescence
apoptosis,
autophagy
can
combat
apoptosis
senescence.
Spatholobi
caulis
(SC)
an
herb
contains
various
active
compounds
are
effective
in
tissue
repair
regeneration,
but
it
not
been
explored
field
IDD.
In
this
study,
was
first
found
SC
boost
reduce
Nucleus
pulposus
cell
(NPCs).
However,
our
animal
revealed
limited
absorption
SC.
To
improve
bioavailability
efficacy
SC,
we
developed
hydrogel
incorporating
quaternary
ammonium
chitosan
(QCS)
oxidized
starch
(OST)
as
carriers
for
The
QCS-OST/SC
exhibits
excellent
compatibility
with
cells,
be
easily
injected,
release
durably.
At
cellular
level,
enhances
viability,
initiates
extracellular
matrix
(ECM),
inhibits
apoptosis.
injection
via
microneedles
(MNs)
into
discs
had
successfully
diminished
rats,
which
shows
broad
potential
treatment
ACS Applied Nano Materials,
Год журнала:
2024,
Номер
7(3), С. 2855 - 2866
Опубликована: Янв. 30, 2024
Herein,
the
authors
report
sodium-ion-conducting
GPEs
dispersed
with
and
without
copper
indium
disulfide
(CuInS2)
nanoforms.
The
standard
solution
casting
technique
has
been
used
to
design
containing
skeleton
of
poly(methyl
methacrylate)
polymer,
sodium
tetrafluoroborate
as
ionic
conducting
source,
ethylene
carbonate
plasticizer,
while
nanospheres
nanowhiskers
CuInS2
served
fillers.
performance
fabricated
investigated
using
electrochemical,
infrared,
thermal
studies.
Ac
impedance
studies
reveal
that
optimized
GPE
1
wt
%
displays
highest
conductivity
0.19
mS
cm–1
at
room
temperature
due
its
more
porous
structure
symmetric
variation
number
particles
particle
size.
Dielectric
modulus
investigations
have
explore
qualitative
ion
dynamics
varied
frequencies.
total
transport
is
found
be
>88%,
confirmation
sodium-ion
movement
during
anodic
cathodic
cycles
established
cyclic
voltammetry
(CV).
CV
also
indicates
an
operating
voltage
range
3.4
V
for
system.
Fourier
transform
infrared
spectroscopy
(FTIR)
revealed
significant
molecular
interactions
among
nanoforms,
polymer
matrix,
solvent,
salt.
Thermal
differential
scanning
calorimetry
(DSC)
analysis
indicate
system
retains
gel
phase
up
388
K,
thermogravimetric
(TGA)
experiment
suggests
a
considerably
lesser
weight
loss
9%
when
∼470
K.
Overall,
introduction
nanoforms
within
significantly
improves
electrochemical
properties
maintaining
decent
properties.
Materials Advances,
Год журнала:
2024,
Номер
5(10), С. 4178 - 4186
Опубликована: Янв. 1, 2024
One-dimensional
(1D)
nanostructures,
including
nanofibers,
nanocubes,
and
nanoplates
of
In
2
S
3
,
1.5
Se
semiconductors,
were
synthesized
using
a
hydrothermal
technique
for
studying
their
photodetector
behaviour.
ACS Omega,
Год журнала:
2024,
Номер
9(33), С. 35431 - 35448
Опубликована: Июнь 24, 2024
The
current
work
aims
to
generate
novel
Schiff
bases
by
reacting
substituted
aldehydes
with
amine
derivatives
catalyzed
a
natural
acid.
developed
compounds
underwent
diverse
physicochemical
analyses
including
liquid
chromatography-mass
spectrometry,
Fourier
transform
infrared
spectroscopy,
scanning
electron
microscopy,
Organometallic
drug
development
is
still
in
its
early
stage,
but
recent
studies
show
that
organometallics
having
iron
as
the
central
atom
have
possibility
of
becoming
good
candidates
because
an
important
micro-nutrient,
and
it
compatible
with
many
biological
systems,
including
human
body.
Being
eco-friendly
Lewis
acid,
can
accept
lone
pair
electrons
from
imino(sp2)-nitrogen,
resultant
iron-imine
complexes
a
interacting
several
proteins
enzymes
humans.
Iron-imine
demonstrated
significant
potential
anticancer,
bactericidal,
fungicidal,
other
medicinal
activities
years.
This
article
systematically
discusses
major
synthetic
methods
pharmacological
potentials
vitro
activity
to
significantly
affect
clinical
performance
2016
date.
In
nutshell,
this
manuscript
offers
simplistic
view
inorganic
chemistry:
for
instance,
presented
"eco-friendly
non-toxic"
metal
(as
opposed
platinum)
will
lead
non-toxic
pharmaceuticals.
The
abundant
literature
on
chelators
shows
complexes,
particularly
if
redox-active
cells,
be
quite
cytotoxic,
which
beneficial
future
targeted
therapies.
While
we
made
every
effort
include
all
related
papers,
any
omission
purely
unintentional.
