Molecules, Год журнала: 2024, Номер 29(19), С. 4776 - 4776
Опубликована: Окт. 9, 2024
The design and development of fluorescent materials for detecting cancer-related enzymes are crucial cancer diagnosis treatment. Herein, we present a substituted rhodamine derivative the chromogenic fluorogenic detection cancer-relevant enzyme
Язык: Английский
ACS Sensors, Год журнала: 2024, Номер 9(9), С. 4898 - 4905
Опубликована: Сен. 5, 2024
Copper ions, implicated in processes such as oxidative stress and inflammation, are believed to play a crucial role cardiovascular disease, prevalent deadly disease. Despite this, current diagnostic methods fail detect early stage disease or track copper ion accumulation, limiting our understanding of the disease's progression. Therefore, development noninvasive techniques image ions is urgently needed enhance precision therapeutic strategies. In this study, we report successful synthesis application ion-activated photoacoustic probe,
Язык: Английский
Процитировано
4
ACS Sensors, Год журнала: 2025, Номер unknown
Опубликована: Март 19, 2025
With the goal of impacting patient quality life and outcomes, sensor science offers significant potential to revolutionize healthcare by providing advances in detection molecular biomarkers for personalized clinical technologies. The community has achieved technical advancements that can impact diagnostics, health monitoring, disease treatment; however, many innovations remain confined laboratory, failing bridge translational gap between research real-world applications. This perspective presents a new direction community, where development centers on needs experiences primary beneficiaries: patients. We provide guidelines resources researchers engage with patients early continuously throughout process inform specifications better align technologies needs, improving their adoption impact. also present examples implementing patient-centered approach planning engagement research. In design impactful sensors patients, must expand focus beyond embrace approach, which will likely lead opportunities collaboration evolution community.
Язык: Английский
Процитировано
0
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2025, Номер unknown, С. 126187 - 126187
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0
ACS Sensors, Год журнала: 2024, Номер unknown
Опубликована: Окт. 4, 2024
Cardiovascular disease (CVD) is a chronic characterized by the accumulation of lipids and fibrous tissue within arterial walls, potentially leading to vascular obstruction an increased risk heart stroke. Hydroxyl radicals play significant role in formation progression CVD as they can instigate lipid peroxidation, resulting cellular damage inflammatory responses. However, precisely detecting hydroxyl lesions presents challenges due their high reactivity short lifespan. Herein, we present development application novel activatable optical probe,
Язык: Английский
Процитировано
3
iScience, Год журнала: 2024, Номер 27(11), С. 111216 - 111216
Опубликована: Окт. 22, 2024
Cardiovascular disease (CVD) is one of the most prevalent health threats globally. Traditional diagnostic methods for CVDs, including electrocardiography, ultrasound, and cardiac magnetic resonance imaging, have inherent limitations in real-time monitoring high-resolution visualization cardiovascular pathophysiology. In recent years, optical imaging technology has gained considerable attention as a non-invasive, high-resolution, solution study diagnosis CVD. This review discusses latest advancements, applications techniques imaging. We compare advantages over traditional modalities especially scrutinize such coherence tomography, photoacoustic fluorescence summarize their investigations atherosclerosis, myocardial infarction, heart valve disease, etc. Additionally, we discuss challenges like deep-tissue high spatiotemporal resolution adjustment, existing solutions multimodal integration, artificial intelligence, enhanced probes. article aims to drive further development technologies provide more precise efficient tools early diagnosis, pathological mechanism exploration, treatment
Язык: Английский
Процитировано
2
Molecules, Год журнала: 2024, Номер 29(19), С. 4776 - 4776
Опубликована: Окт. 9, 2024
The design and development of fluorescent materials for detecting cancer-related enzymes are crucial cancer diagnosis treatment. Herein, we present a substituted rhodamine derivative the chromogenic fluorogenic detection cancer-relevant enzyme
Язык: Английский
Процитировано
0