Activatable Photoacoustic/Near-Infrared Probes for the Detection of Copper Ions of Cardiovascular Disease In Vivo and in Urine
Kai Wang,
No information about this author
Ke-Feng Gu,
No information about this author
Jie Cao
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et al.
ACS Sensors,
Journal Year:
2024,
Volume and Issue:
9(9), P. 4898 - 4905
Published: Sept. 5, 2024
Copper
ions,
implicated
in
processes
such
as
oxidative
stress
and
inflammation,
are
believed
to
play
a
crucial
role
cardiovascular
disease,
prevalent
deadly
disease.
Despite
this,
current
diagnostic
methods
fail
detect
early
stage
disease
or
track
copper
ion
accumulation,
limiting
our
understanding
of
the
disease's
progression.
Therefore,
development
noninvasive
techniques
image
ions
is
urgently
needed
enhance
precision
therapeutic
strategies.
In
this
study,
we
report
successful
synthesis
application
ion-activated
photoacoustic
probe,
Language: Английский
A Patient-Centered Approach in Sensor Science: Embracing Patient Engagement for Translational Clinical Technologies
Alana F. Ogata,
No information about this author
Julia Kramer
No information about this author
ACS Sensors,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 19, 2025
With
the
goal
of
impacting
patient
quality
life
and
outcomes,
sensor
science
offers
significant
potential
to
revolutionize
healthcare
by
providing
advances
in
detection
molecular
biomarkers
for
personalized
clinical
technologies.
The
community
has
achieved
technical
advancements
that
can
impact
diagnostics,
health
monitoring,
disease
treatment;
however,
many
innovations
remain
confined
laboratory,
failing
bridge
translational
gap
between
research
real-world
applications.
This
perspective
presents
a
new
direction
community,
where
development
centers
on
needs
experiences
primary
beneficiaries:
patients.
We
provide
guidelines
resources
researchers
engage
with
patients
early
continuously
throughout
process
inform
specifications
better
align
technologies
needs,
improving
their
adoption
impact.
also
present
examples
implementing
patient-centered
approach
planning
engagement
research.
In
design
impactful
sensors
patients,
must
expand
focus
beyond
embrace
approach,
which
will
likely
lead
opportunities
collaboration
evolution
community.
Language: Английский
A fluorescent probe for detecting carboxylesterase level on investigating Chinese medicine water decoction efficacy
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy,
Journal Year:
2025,
Volume and Issue:
unknown, P. 126187 - 126187
Published: April 1, 2025
Language: Английский
Dual-Activated Photoacoustic Probe for Reliably Detecting Hydroxyl Radical in Ischemic Cardiovascular Disease in Mouse and Human Samples
Fang-Kun Yang,
No information about this author
Jie Cao,
No information about this author
Ting Zhang
No information about this author
et al.
ACS Sensors,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 4, 2024
Cardiovascular
disease
(CVD)
is
a
chronic
characterized
by
the
accumulation
of
lipids
and
fibrous
tissue
within
arterial
walls,
potentially
leading
to
vascular
obstruction
an
increased
risk
heart
stroke.
Hydroxyl
radicals
play
significant
role
in
formation
progression
CVD
as
they
can
instigate
lipid
peroxidation,
resulting
cellular
damage
inflammatory
responses.
However,
precisely
detecting
hydroxyl
lesions
presents
challenges
due
their
high
reactivity
short
lifespan.
Herein,
we
present
development
application
novel
activatable
optical
probe,
Language: Английский
Diagnostic and Therapeutic Optical Imaging in Cardiovascular Diseases
Weiran Pang,
No information about this author
Chuqi Yuan,
No information about this author
Tianting Zhong
No information about this author
et al.
iScience,
Journal Year:
2024,
Volume and Issue:
27(11), P. 111216 - 111216
Published: Oct. 22, 2024
Cardiovascular
disease
(CVD)
is
one
of
the
most
prevalent
health
threats
globally.
Traditional
diagnostic
methods
for
CVDs,
including
electrocardiography,
ultrasound,
and
cardiac
magnetic
resonance
imaging,
have
inherent
limitations
in
real-time
monitoring
high-resolution
visualization
cardiovascular
pathophysiology.
In
recent
years,
optical
imaging
technology
has
gained
considerable
attention
as
a
non-invasive,
high-resolution,
solution
study
diagnosis
CVD.
This
review
discusses
latest
advancements,
applications
techniques
imaging.
We
compare
advantages
over
traditional
modalities
especially
scrutinize
such
coherence
tomography,
photoacoustic
fluorescence
summarize
their
investigations
atherosclerosis,
myocardial
infarction,
heart
valve
disease,
etc.
Additionally,
we
discuss
challenges
like
deep-tissue
high
spatiotemporal
resolution
adjustment,
existing
solutions
multimodal
integration,
artificial
intelligence,
enhanced
probes.
article
aims
to
drive
further
development
technologies
provide
more
precise
efficient
tools
early
diagnosis,
pathological
mechanism
exploration,
treatment
Language: Английский
Turn-On Fluorescence Probe for Cancer-Related γ-Glutamyltranspeptidase Detection
Molecules,
Journal Year:
2024,
Volume and Issue:
29(19), P. 4776 - 4776
Published: Oct. 9, 2024
The
design
and
development
of
fluorescent
materials
for
detecting
cancer-related
enzymes
are
crucial
cancer
diagnosis
treatment.
Herein,
we
present
a
substituted
rhodamine
derivative
the
chromogenic
fluorogenic
detection
cancer-relevant
enzyme
Language: Английский