Turn-On Fluorescence Probe for Cancer-Related γ-Glutamyltranspeptidase Detection DOI Creative Commons
Muhammad Saleem, Muhammad Hanif, Samuel Bonne

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(19), P. 4776 - 4776

Published: Oct. 9, 2024

The design and development of fluorescent materials for detecting cancer-related enzymes are crucial cancer diagnosis treatment. Herein, we present a substituted rhodamine derivative the chromogenic fluorogenic detection cancer-relevant enzyme

Language: Английский

Activatable Photoacoustic/Near-Infrared Probes for the Detection of Copper Ions of Cardiovascular Disease In Vivo and in Urine DOI
Kai Wang,

Ke-Feng Gu,

Jie Cao

et al.

ACS Sensors, Journal Year: 2024, Volume and Issue: 9(9), P. 4898 - 4905

Published: Sept. 5, 2024

Copper ions, implicated in processes such as oxidative stress and inflammation, are believed to play a crucial role cardiovascular disease, prevalent deadly disease. Despite this, current diagnostic methods fail detect early stage disease or track copper ion accumulation, limiting our understanding of the disease's progression. Therefore, development noninvasive techniques image ions is urgently needed enhance precision therapeutic strategies. In this study, we report successful synthesis application ion-activated photoacoustic probe,

Language: Английский

Citations

4

A Patient-Centered Approach in Sensor Science: Embracing Patient Engagement for Translational Clinical Technologies DOI

Alana F. Ogata,

Julia Kramer

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: March 19, 2025

With the goal of impacting patient quality life and outcomes, sensor science offers significant potential to revolutionize healthcare by providing advances in detection molecular biomarkers for personalized clinical technologies. The community has achieved technical advancements that can impact diagnostics, health monitoring, disease treatment; however, many innovations remain confined laboratory, failing bridge translational gap between research real-world applications. This perspective presents a new direction community, where development centers on needs experiences primary beneficiaries: patients. We provide guidelines resources researchers engage with patients early continuously throughout process inform specifications better align technologies needs, improving their adoption impact. also present examples implementing patient-centered approach planning engagement research. In design impactful sensors patients, must expand focus beyond embrace approach, which will likely lead opportunities collaboration evolution community.

Language: Английский

Citations

0

A fluorescent probe for detecting carboxylesterase level on investigating Chinese medicine water decoction efficacy DOI
Jingyi Shi, Chaoyue Wang, Yi-Fan Xia

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2025, Volume and Issue: unknown, P. 126187 - 126187

Published: April 1, 2025

Language: Английский

Citations

0

Dual-Activated Photoacoustic Probe for Reliably Detecting Hydroxyl Radical in Ischemic Cardiovascular Disease in Mouse and Human Samples DOI

Fang-Kun Yang,

Jie Cao,

Ting Zhang

et al.

ACS Sensors, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 4, 2024

Cardiovascular disease (CVD) is a chronic characterized by the accumulation of lipids and fibrous tissue within arterial walls, potentially leading to vascular obstruction an increased risk heart stroke. Hydroxyl radicals play significant role in formation progression CVD as they can instigate lipid peroxidation, resulting cellular damage inflammatory responses. However, precisely detecting hydroxyl lesions presents challenges due their high reactivity short lifespan. Herein, we present development application novel activatable optical probe,

Language: Английский

Citations

3

Diagnostic and Therapeutic Optical Imaging in Cardiovascular Diseases DOI Creative Commons
Weiran Pang,

Chuqi Yuan,

Tianting Zhong

et al.

iScience, Journal Year: 2024, Volume and Issue: 27(11), P. 111216 - 111216

Published: Oct. 22, 2024

Cardiovascular disease (CVD) is one of the most prevalent health threats globally. Traditional diagnostic methods for CVDs, including electrocardiography, ultrasound, and cardiac magnetic resonance imaging, have inherent limitations in real-time monitoring high-resolution visualization cardiovascular pathophysiology. In recent years, optical imaging technology has gained considerable attention as a non-invasive, high-resolution, solution study diagnosis CVD. This review discusses latest advancements, applications techniques imaging. We compare advantages over traditional modalities especially scrutinize such coherence tomography, photoacoustic fluorescence summarize their investigations atherosclerosis, myocardial infarction, heart valve disease, etc. Additionally, we discuss challenges like deep-tissue high spatiotemporal resolution adjustment, existing solutions multimodal integration, artificial intelligence, enhanced probes. article aims to drive further development technologies provide more precise efficient tools early diagnosis, pathological mechanism exploration, treatment

Language: Английский

Citations

2

Turn-On Fluorescence Probe for Cancer-Related γ-Glutamyltranspeptidase Detection DOI Creative Commons
Muhammad Saleem, Muhammad Hanif, Samuel Bonne

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(19), P. 4776 - 4776

Published: Oct. 9, 2024

The design and development of fluorescent materials for detecting cancer-related enzymes are crucial cancer diagnosis treatment. Herein, we present a substituted rhodamine derivative the chromogenic fluorogenic detection cancer-relevant enzyme

Language: Английский

Citations

0