Metformin and Other Pharmaceuticals Widespread in Wadeable Streams of the Southeastern United States

Environmental Science & Technology Letters, Год журнала: 2016, Номер 3(6), С. 243 - 249

Опубликована: Май 24, 2016

Pharmaceutical contaminants are growing aquatic-health concerns and largely attributed to wastewater treatment facility (WWTF) discharges. Five biweekly water samples from 59 small Piedmont (United States) streams were analyzed for 108 pharmaceuticals degradates using high-performance liquid chromatography tandem mass spectrometry. The antidiabetic metformin was detected in 89% of at 97% sites. At least one pharmaceutical every site (median 6, maximum 45), several ≥10% sites concentrations reported affect multiple aquatic end points. Maximal cumulative (all compounds) per ranged 17 16000 ng L–1. Watershed urbanization, table depth, soil thickness, WWTF metrics correlated significantly with in-stream contamination. Comparable detections without permitted discharges demonstrate the importance non-WWTF sources need broad-scale mitigation. results highlight a fundamental biochemical link between global human-health crises like diabetes ecosystem health.

Язык: Английский

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Emerging environmental health risks associated with the land application of biosolids: a scoping review

Environmental Health, Год журнала: 2023, Номер 22(1)

Опубликована: Авг. 21, 2023

Abstract Background Over 40% of the six million dry metric tons sewage sludge, often referred to as biosolids, produced annually in United States is land applied. Biosolids serve a sink for emerging pollutants which can be toxic and persist environment, yet their fate after application impacts on human health have not been well studied. These gaps our understanding are exacerbated by absence systematic monitoring programs defined standards protection. Methods The purpose this paper call critical attention knowledge that currently exist regarding biosolids underscore need evidence-based testing regulatory frameworks protection when A scoping review methodology was used identify research conducted within last decade, current standards, government publications applied biosolids. Results Current indicates persistent organic compounds, or pollutants, found pharmaceuticals personal care products, microplastics, per- polyfluoroalkyl substances (PFAS) potential contaminate ground surface water, uptake these from soil amended result contamination food sources. Advanced technologies remove contaminants wastewater treatment plant influent, effluent, destined along with tools detect quantify Conclusions To address risks, there needs significant investment ongoing infrastructure support advancements treatment; expanded manufacture use sustainable products; increased public communication risks associated overuse plastics; development implementation regulations protective environment.

Язык: Английский

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Cu–TiO2 nanorods with enhanced ultraviolet- and visible-light photoactivity for bisphenol A degradation

Journal of Hazardous Materials, Год журнала: 2014, Номер 277, С. 84 - 92

Опубликована: Фев. 2, 2014

Язык: Английский

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In-Stream Attenuation of Neuro-Active Pharmaceuticals and Their Metabolites

Environmental Science & Technology, Год журнала: 2013, Номер 47(17), С. 9781 - 9790

Опубликована: Авг. 16, 2013

In-stream attenuation was determined for 14 neuro-active pharmaceuticals and associated metabolites. Lagrangian sampling, which follows a parcel of water as it moves downstream, used to link hydrological chemical transformation processes. Wastewater loading compounds varied considerably over span several hours, thus sampling regime verify that the being sampled mechanism developed correct measured concentrations if not. 5.4-km evaluated reach could be modeled pseudo-first-order decay 11 pharmaceutical compounds, illustrating capacity streams reduce conveyance downstream. Fluoxetine N-desmethyl citalopram were most rapidly attenuated (t1/2 = 3.6 ± 0.3 h, 4.0 0.2 respectively). Lamotrigine, 10,11,-dihydro-10,11,-dihydroxy-carbamazepine, carbamazepine persistent 12 2.0 2.6 21 4.5 Parent (e.g., buproprion, carbamazepine, lamotrigine) generally more relative their Several (citalopram, venlafaxine, O-desmethyl-venlafaxine) not attenuated. It postulated primary removal these interaction with bed sediments stream biofilms, based on in biofilms column experiment using sediments.

Язык: Английский

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Mycotoxins: Diffuse and point source contributions of natural contaminants of emerging concern to streams

The Science of The Total Environment, Год журнала: 2013, Номер 470-471, С. 669 - 676

Опубликована: Окт. 29, 2013

Язык: Английский

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An environmental oestrogen disrupts fish population dynamics through direct and transgenerational effects on survival and fecundity

Journal of Applied Ecology, Год журнала: 2014, Номер 51(3), С. 582 - 591

Опубликована: Фев. 20, 2014

Summary Increased need for water and projected declines in precipitation due to climate change could leave waterways increasingly dominated by wastewater effluent. Understanding how components of influence fish populations is necessary effective conservation management. Despite research demonstrating effects oestrogens, such as 17α‐ethynylestradiol ( EE 2), on physiology population failure, the generality responses uncertain underlying mechanisms affecting are unknown. 2 steroid oestrogen human contraceptive pills has been measured up 11 ng L −1 environment. We identify disrupted dynamics direct transgenerational survival fecundity. conducted a year‐long study three generations fathead minnows Pimephales promelas Rafinesque aquatic mesocosms laboratory aquaria. added environmentally relevant concentrations daily using static renewal, which approximates pulsed exposure that experience natural systems. (3·2 ) reduced F0 male 17% (48% lower than controls) juvenile production 40% compared controls. F1 continuously exposed failed reproduce, reproduction transferred clean was 70–99% less F2 larval survival, only germ cells their parents, 51–97% The indirect effect suggests possibility 2. Synthesis applications . Our results suggest 2) may not recover from exposure. Management short‐lived highly fecund fishes should be prioritized protect embryo through gonadal differentiation. Reducing effluent will possible many situations; hence, breeding rearing habitat unpolluted tributaries or reaches needed. Additionally, resource managers enhance connectivity rivers facilitate immigration. Finally, investment advanced processing technology improve removal bioactive chemicals provide baseline regulatory agencies consider when assessing ecological environmental our approach evaluating population‐level widely applied other contaminants.

Язык: Английский

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Enhanced visible-light-responsive photodegradation of bisphenol A by Cu, N-codoped titanate nanotubes prepared by microwave-assisted hydrothermal method

Journal of Hazardous Materials, Год журнала: 2016, Номер 322, С. 254 - 262

Опубликована: Март 2, 2016

Язык: Английский

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Enhanced photoactivity of Cu-deposited titanate nanotubes for removal of bisphenol A

Applied Catalysis B Environment and Energy, Год журнала: 2012, Номер 129, С. 48 - 55

Опубликована: Сен. 16, 2012

Язык: Английский

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Whole organism responses and intersex severity in rainbow darter (Etheostoma caeruleum) following exposures to municipal wastewater in the Grand River basin, ON, Canada. Part A

Aquatic Toxicology, Год журнала: 2014, Номер 159, С. 290 - 301

Опубликована: Дек. 3, 2014

Язык: Английский

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Reduction of Intersex in a Wild Fish Population in Response to Major Municipal Wastewater Treatment Plant Upgrades

Environmental Science & Technology, Год журнала: 2016, Номер 51(3), С. 1811 - 1819

Опубликована: Дек. 27, 2016

Intersex in fish downstream of municipal wastewater treatment plants (MWWTPs) is a global concern. Consistent high rates intersex male rainbow darter (Etheostoma caeruleum) have been reported for several years the Grand River, southern Ontario, Canada, close proximity to two MWWTPs. The larger MWWTP (Kitchener) recently underwent upgrades that included conversion from carbonaceous activated sludge nitrifying process. This created unique opportunity assess whether designed improve effluent quality could also remediate previously observed wild fish. Multiple (2007-2012) data on collected before at sites associated with outfall were compared postupgrade (2013-2015). These resulted reduction 70 100% incidence (preupgrade) <10% years. Although cause remains unknown, indicators including nutrients, pharmaceuticals, and estrogenicity improved after upgrades. study demonstrated investment was an immediate change biological responses receiving environment. important finding considering tremendous cost infrastructure.

Язык: Английский

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