Angewandte Chemie International Edition,
Год журнала:
2022,
Номер
61(41)
Опубликована: Авг. 27, 2022
Abstract
As
the
aromatic
tryptophan
(Trp)
side
chain
plays
a
pivotal
role
in
influencing
structure
and
function
of
peptides
proteins,
it
has
become
an
attractive
target
for
late‐stage
modification
these
important
biomolecules.
Herein,
we
report
electrochemical
approach
functionalization
containing
Trp
through
manganese‐catalyzed
tandem
radical
azidation/heterocyclization.
This
oxidative
strategy
provides
access
to
azide‐substituted
tetrazolo[1,5‐
]indole‐containing
with
broad
functional
group
tolerance,
high
site
selectivity,
good
yields
products
(up
87
%)
under
mild
buffer
conditions.
Moreover,
modified
Trp‐containing
bearing
azide
functionality
are
promising
building
blocks,
paving
way
construction
various
derivatives,
such
as
“click”
chemistry
products.
Nature Communications,
Год журнала:
2022,
Номер
13(1)
Опубликована: Сен. 28, 2022
The
design
and
synthesis
of
novel
energetic
compounds
with
integrated
properties
high
density,
energy,
good
thermal
stability
sensitivities
is
particularly
challenging
due
to
the
inherent
contradiction
between
energy
safety
for
compounds.
In
this
study,
a
structure
4-amino-7,8-dinitropyrazolo-[5,1-d]
[1,2,3,5]-tetrazine
2-oxide
(BITE-101)
designed
synthesized
in
three
steps.
With
help
complementary
advantages
different
explosophoric
groups
diverse
weak
interactions,
BITE-101
superior
benchmark
explosive
HMX
all
respects,
including
higher
density
1.957
g·cm
Chemical Communications,
Год журнала:
2024,
Номер
60(12), С. 1646 - 1649
Опубликована: Янв. 1, 2024
A
series
of
nitrogen-rich
fused
energetic
materials
were
synthesized
from
commercially
available
inexpensive
starting
and
fully
characterized
using
1
H
13
C
NMR,
IR
spectroscopy,
elemental
analysis,
DSC.
Organic Letters,
Год журнала:
2024,
Номер
26(9), С. 1952 - 1958
Опубликована: Фев. 27, 2024
Because
of
environmental
and
health
impacts,
there
is
an
ongoing
necessity
to
develop
sustainable
primary
explosives
replace
existing
lead-based
analogues.
Now
we
describe
a
potential
explosive,
dipotassium
4,6-dinitro-5,7-dioxidobenzo[c][1,2,5]oxadiazole
1-oxide
(K
JACS Au,
Год журнала:
2025,
Номер
5(2), С. 1031 - 1038
Опубликована: Янв. 23, 2025
A
primary
explosive
is
a
perfect
chemical
compound
for
starting
ignition
in
military
and
commercial
uses.
Over
the
past
century,
quest
lead-free,
environmentally
friendly
explosives
has
been
significant
challenge
long-standing
goal.
Here,
an
innovative
organic
explosive,
(E)-1,2-bis(3-azido-5-(trifluoromethyl)-4H-1,2,4-triazol-4-yl)diazene
(4),
designed
synthesized
through
straightforward
three-step
reaction
from
commercially
available
reagents.
Importantly,
this
integrated
two
trifluoromethyl
azido
groups
into
N,N′-azo-1,2,4-triazole
backbone
to
enhance
performance
safety.
With
combination,
it
meets
stringent
criteria
safer,
explosives:
being
metal
perchlorate-free,
possessing
high
density,
excellent
priming
ability,
unique
sensitivities
nonexplosive
stimuli.
It
shows
robust
environmental
resistance,
good
thermal
stability,
effective
detonation
also
can
be
effectively
initiated
with
laser.
Moreover,
test,
4
successfully
detonated
500
mg
of
PETN
ultralow
minimum
primer
charge
(MPC)
40
mg,
similar
traditional
LA
(MPC:
mg)
outperforming
metal-free
ICM-103
60
DDNP
70
mg).
The
power,
combined
its
synthesis,
cost-effectiveness,
easy
large-scale
manufacturing,
makes
superior
alternative
currently
used
such
as
lead
azide
(LA)
diazodinitrophenol
(DDNP).
Journal of Materials Chemistry A,
Год журнала:
2021,
Номер
9(20), С. 12291 - 12298
Опубликована: Янв. 1, 2021
A
highly
efficient
strategy
of
two
different
types
nitrogen-rich
heterocyclic
energetic
compounds,
featuring
a
single
NH-bridge
(–NH–)
and
fused
ring,
was
demonstrated
by
virtue
Dimroth
rearrangement
reactions.
Crystal Growth & Design,
Год журнала:
2021,
Номер
21(12), С. 6619 - 6634
Опубликована: Ноя. 9, 2021
Understanding
intermolecular
interactions
is
fundamental
to
understanding
the
molecular
stacking
structures
and
some
properties
of
energetic
crystals,
such
as
density,
energy,
mechanics,
sensitivity.
The
Hirshfeld
surface
method
a
straightforward
tool
reveal
nowadays
has
become
increasingly
popular
in
field
materials.
This
article
highlights
wide
range
applications
this
describing
including
hydrogen
bonding,
π-stacking,
halogen
lone
pair−π
(n−π)
stacking,
patterns,
predicting
shear
sliding
characteristic
further
impact
Meanwhile,
roughness
quantitative
description
interaction
strength
method,
main
shortcoming,
pointed
out
herein.
Thus,
work
expected
guide
right
full
use
method.
Besides,
we
present
perspective
about
using
rapidly
screen
mode
sensitivity;
thus,
fast
screening
two
most
important
can
be
implemented,
combination
with
existing
mature
energy
prediction
methods
based
on
components.
Thereby,
more
reliable
procedure
an
additional
consideration
pattern
will
produced,
setting
basis
for
data-driven
crystal
engineering
research
Defence Technology,
Год журнала:
2021,
Номер
17(6), С. 1995 - 2010
Опубликована: Фев. 9, 2021
Heterocyclic
skeleton
(Azoles)
and
different
energetic
groups
containing
high
performing
explosives
are
highly
emerged
in
recent
years
to
meet
the
challenging
requirements
of
materials
both
military
civilian
applications
with
improved
performance.
For
this
purpose
tetrazole
(Azole)
is
identified
as
an
attractive
heterocyclic
backbone
functional
nitro
(-NO2),
nitrato
(-ONO2),
nitrimino
(-NNO2),
nitramino
(–NH–NO2)
replace
traditionally
used
explosives.
The
based
compounds
having
these
demonstrated
advanced
performance
(detonation
velocity
pressure),
densities,
heat
formation
(HOF)
became
a
potential
replacement
traditional
such
RDX.
This
review
presents
summary
recently
reported
nitro-tetrazole
poly-nitro,
di/mono-nitro,
nitrato/nitramino/nitrimino,
bridged/bis/di
groups,
describing
their
preparation
methods,
advance
properties,
further
high-performing
explosives,
especially
those
last
decade.
aims
provide
fresh
concept
for
designing
together
major
challenges
perspectives.
ACS Applied Materials & Interfaces,
Год журнала:
2022,
Номер
14(44), С. 49898 - 49908
Опубликована: Окт. 26, 2022
Thermally
stable
energetic
materials
have
broad
applications
in
the
deep
mining,
oil
and
natural
exploration,
aerospace
industries.
The
quest
for
thermally
(heat-resistant)
with
high
energy
output
low
sensitivity
has
fascinated
many
researchers
worldwide.
In
this
study,
two
different
series
of
salts
based
on
pyrazole–oxadiazole
pyrazole–triazole
(3–23)
explosophoric
groups
been
synthesized
a
simple
straightforward
manner.
All
newly
compounds
were
fully
characterized
by
IR,
ESI-MS,
multinuclear
NMR
spectroscopy,
elemental
analysis,
thermogravimetric
analysis–differential
scanning
calorimetry
measurements.
structures
3,
7,
22
supported
single-crystal
X-ray
diffraction
studies.
density,
heat
formation,
properties
(detonation
velocity
detonation
pressure)
all
range
between
1.75
1.94
g
cm–3,
0.73
to
2.44
kJ
g–1,
7689
9139
m
s–1,
23.3
31.5
GPa,
respectively.
are
insensitive
impact
(>30
J)
friction
(>360
N).
addition,
4,
6,
10,
14,
17,
21,
22,
23
show
onset
decomposition
temperature
(Td
238
397
°C)
than
benchmark
RDX
=
210
°C),
HMX
(279
HNS
(318
°C).
It
is
noteworthy
that
backbones
greatly
influence
their
physicochemical
properties.
Overall,
study
offers
perspective
nitrogen-rich
explores
relationship
structure
performance.
