Tandem Electrochemical Oxidative Azidation/Heterocyclization of Tryptophan‐Containing Peptides under Buffer Conditions DOI
Yiyi Weng, Xiaobin Xu,

Hantao Chen

и другие.

Angewandte Chemie International Edition, Год журнала: 2022, Номер 61(41)

Опубликована: Авг. 27, 2022

Abstract As the aromatic tryptophan (Trp) side chain plays a pivotal role in influencing structure and function of peptides proteins, it has become an attractive target for late‐stage modification these important biomolecules. Herein, we report electrochemical approach functionalization containing Trp through manganese‐catalyzed tandem radical azidation/heterocyclization. This oxidative strategy provides access to azide‐substituted tetrazolo[1,5‐ ]indole‐containing with broad functional group tolerance, high site selectivity, good yields products (up 87 %) under mild buffer conditions. Moreover, modified Trp‐containing bearing azide functionality are promising building blocks, paving way construction various derivatives, such as “click” chemistry products.

Язык: Английский

Tri-explosophoric groups driven fused energetic heterocycles featuring superior energetic and safety performances outperforms HMX DOI Creative Commons
Jie Li, Yubing Liu,

Wenqi Ma

и другие.

Nature Communications, Год журнала: 2022, Номер 13(1)

Опубликована: Сен. 28, 2022

The design and synthesis of novel energetic compounds with integrated properties high density, energy, good thermal stability sensitivities is particularly challenging due to the inherent contradiction between energy safety for compounds. In this study, a structure 4-amino-7,8-dinitropyrazolo-[5,1-d] [1,2,3,5]-tetrazine 2-oxide (BITE-101) designed synthesized in three steps. With help complementary advantages different explosophoric groups diverse weak interactions, BITE-101 superior benchmark explosive HMX all respects, including higher density 1.957 g·cm

Язык: Английский

Процитировано

112

Supramolecular polymers: Recent advances based on the types of underlying interactions DOI
Hui‐Qing Peng,

Wenping Zhu,

Wu‐Jie Guo

и другие.

Progress in Polymer Science, Год журнала: 2022, Номер 137, С. 101635 - 101635

Опубликована: Дек. 14, 2022

Язык: Английский

Процитировано

72

Zwitterionic fused pyrazolo-triazole based high performing energetic materials DOI
Parasar Kumar, Navaneet Kumar, Vikas D. Ghule

и другие.

Chemical Communications, Год журнала: 2024, Номер 60(12), С. 1646 - 1649

Опубликована: Янв. 1, 2024

A series of nitrogen-rich fused energetic materials were synthesized from commercially available inexpensive starting and fully characterized using 1 H 13 C NMR, IR spectroscopy, elemental analysis, DSC.

Язык: Английский

Процитировано

19

Pushing the Limit of Oxygen Balance on a Benzofuroxan Framework: K2DNDP as an Extremely Dense and Thermally Stable Material as a Substitute for Lead Azide DOI
Krishna Pandey,

Atharva Tiwari,

Jatinder Singh

и другие.

Organic Letters, Год журнала: 2024, Номер 26(9), С. 1952 - 1958

Опубликована: Фев. 27, 2024

Because of environmental and health impacts, there is an ongoing necessity to develop sustainable primary explosives replace existing lead-based analogues. Now we describe a potential explosive, dipotassium 4,6-dinitro-5,7-dioxidobenzo[c][1,2,5]oxadiazole 1-oxide (K

Язык: Английский

Процитировано

19

Interfacial self-assembling of nano-TATB@PDA embedded football-like CL-20 co-particles with reduced sensitivity DOI
Zhihua Xue, Ruixuan Xu,

Zikangping Wang

и другие.

Chemical Engineering Journal, Год журнала: 2024, Номер 488, С. 151010 - 151010

Опубликована: Апрель 4, 2024

Язык: Английский

Процитировано

18

Highly Promising Primary Explosive: A Metal-Free, Fluoro-Substituted Azo-Triazole with Unmatched Safety and Performance DOI Creative Commons
Abhishek Kumar Yadav,

Sonali Kukreja,

Srinivas Dharavath

и другие.

JACS Au, Год журнала: 2025, Номер 5(2), С. 1031 - 1038

Опубликована: Янв. 23, 2025

A primary explosive is a perfect chemical compound for starting ignition in military and commercial uses. Over the past century, quest lead-free, environmentally friendly explosives has been significant challenge long-standing goal. Here, an innovative organic explosive, (E)-1,2-bis(3-azido-5-(trifluoromethyl)-4H-1,2,4-triazol-4-yl)diazene (4), designed synthesized through straightforward three-step reaction from commercially available reagents. Importantly, this integrated two trifluoromethyl azido groups into N,N′-azo-1,2,4-triazole backbone to enhance performance safety. With combination, it meets stringent criteria safer, explosives: being metal perchlorate-free, possessing high density, excellent priming ability, unique sensitivities nonexplosive stimuli. It shows robust environmental resistance, good thermal stability, effective detonation also can be effectively initiated with laser. Moreover, test, 4 successfully detonated 500 mg of PETN ultralow minimum primer charge (MPC) 40 mg, similar traditional LA (MPC: mg) outperforming metal-free ICM-103 60 DDNP 70 mg). The power, combined its synthesis, cost-effectiveness, easy large-scale manufacturing, makes superior alternative currently used such as lead azide (LA) diazodinitrophenol (DDNP).

Язык: Английский

Процитировано

3

Tunable Dimroth rearrangement of versatile 1,2,3-triazoles towards high-performance energetic materials DOI
Shangbiao Feng, Ping Yin, Chunlin He

и другие.

Journal of Materials Chemistry A, Год журнала: 2021, Номер 9(20), С. 12291 - 12298

Опубликована: Янв. 1, 2021

A highly efficient strategy of two different types nitrogen-rich heterocyclic energetic compounds, featuring a single NH-bridge (–NH–) and fused ring, was demonstrated by virtue Dimroth rearrangement reactions.

Язык: Английский

Процитировано

82

Hirshfeld Surface Method and Its Application in Energetic Crystals DOI
Shijie Li, Rupeng Bu, Ruijun Gou

и другие.

Crystal Growth & Design, Год журнала: 2021, Номер 21(12), С. 6619 - 6634

Опубликована: Ноя. 9, 2021

Understanding intermolecular interactions is fundamental to understanding the molecular stacking structures and some properties of energetic crystals, such as density, energy, mechanics, sensitivity. The Hirshfeld surface method a straightforward tool reveal nowadays has become increasingly popular in field materials. This article highlights wide range applications this describing including hydrogen bonding, π-stacking, halogen lone pair−π (n−π) stacking, patterns, predicting shear sliding characteristic further impact Meanwhile, roughness quantitative description interaction strength method, main shortcoming, pointed out herein. Thus, work expected guide right full use method. Besides, we present perspective about using rapidly screen mode sensitivity; thus, fast screening two most important can be implemented, combination with existing mature energy prediction methods based on components. Thereby, more reliable procedure an additional consideration pattern will produced, setting basis for data-driven crystal engineering research

Язык: Английский

Процитировано

80

Nitro-tetrazole based high performing explosives: Recent overview of synthesis and energetic properties DOI Creative Commons
Saira Manzoor,

Qamar‐un‐Nisa Tariq,

Xin Yin

и другие.

Defence Technology, Год журнала: 2021, Номер 17(6), С. 1995 - 2010

Опубликована: Фев. 9, 2021

Heterocyclic skeleton (Azoles) and different energetic groups containing high performing explosives are highly emerged in recent years to meet the challenging requirements of materials both military civilian applications with improved performance. For this purpose tetrazole (Azole) is identified as an attractive heterocyclic backbone functional nitro (-NO2), nitrato (-ONO2), nitrimino (-NNO2), nitramino (–NH–NO2) replace traditionally used explosives. The based compounds having these demonstrated advanced performance (detonation velocity pressure), densities, heat formation (HOF) became a potential replacement traditional such RDX. This review presents summary recently reported nitro-tetrazole poly-nitro, di/mono-nitro, nitrato/nitramino/nitrimino, bridged/bis/di groups, describing their preparation methods, advance properties, further high-performing explosives, especially those last decade. aims provide fresh concept for designing together major challenges perspectives.

Язык: Английский

Процитировано

66

Promising Thermally Stable Energetic Materials with the Combination of Pyrazole–1,3,4-Oxadiazole and Pyrazole–1,2,4-Triazole Backbones: Facile Synthesis and Energetic Performance DOI
Abhishek Kumar Yadav, Vikas D. Ghule, Srinivas Dharavath

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2022, Номер 14(44), С. 49898 - 49908

Опубликована: Окт. 26, 2022

Thermally stable energetic materials have broad applications in the deep mining, oil and natural exploration, aerospace industries. The quest for thermally (heat-resistant) with high energy output low sensitivity has fascinated many researchers worldwide. In this study, two different series of salts based on pyrazole–oxadiazole pyrazole–triazole (3–23) explosophoric groups been synthesized a simple straightforward manner. All newly compounds were fully characterized by IR, ESI-MS, multinuclear NMR spectroscopy, elemental analysis, thermogravimetric analysis–differential scanning calorimetry measurements. structures 3, 7, 22 supported single-crystal X-ray diffraction studies. density, heat formation, properties (detonation velocity detonation pressure) all range between 1.75 1.94 g cm–3, 0.73 to 2.44 kJ g–1, 7689 9139 m s–1, 23.3 31.5 GPa, respectively. are insensitive impact (>30 J) friction (>360 N). addition, 4, 6, 10, 14, 17, 21, 22, 23 show onset decomposition temperature (Td 238 397 °C) than benchmark RDX = 210 °C), HMX (279 HNS (318 °C). It is noteworthy that backbones greatly influence their physicochemical properties. Overall, study offers perspective nitrogen-rich explores relationship structure performance.

Язык: Английский

Процитировано

61