Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(42), С. 28783 - 28794
Опубликована: Окт. 11, 2024
Currently
used
drugs
for
glioblastoma
(GBM)
treatments
are
ineffective,
primarily
due
to
the
significant
challenges
posed
by
strong
drug
resistance,
poor
blood-brain
barrier
(BBB)
permeability,
and
lack
of
tumor
specificity.
Here,
we
report
two
cationic
fluorescent
anticancer
agents
(TriPEX-ClO
Chemical Science,
Год журнала:
2024,
Номер
15(18), С. 6752 - 6762
Опубликована: Янв. 1, 2024
A
mitochondria-localizing
iridium(
iii
)
photosensitizer
produces
singlet
oxygen
and
superoxide
anion
radicals
upon
two-photon
irradiation,
disrupting
the
mitochondrial
respiratory
chain
inducing
ferritinophagy
immunogenic
cell
death.
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(42), С. 28783 - 28794
Опубликована: Окт. 11, 2024
Currently
used
drugs
for
glioblastoma
(GBM)
treatments
are
ineffective,
primarily
due
to
the
significant
challenges
posed
by
strong
drug
resistance,
poor
blood-brain
barrier
(BBB)
permeability,
and
lack
of
tumor
specificity.
Here,
we
report
two
cationic
fluorescent
anticancer
agents
(TriPEX-ClO