Recent advances in hydrogen atom transfer induced C(sp3)–H functionalizations initiated by radical addition to alkynes
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
11(4), С. 1232 - 1250
Опубликована: Дек. 28, 2023
Recent
advances
in
HAT-induced
C(sp
3
)–H
functionalizations
triggered
by
radical
addition
to
alkynes,
including
5-
exo-trig
,
endo-trig
4-
and
6-
cyclization
cascades,
intermolecular
functionalizations,
are
summarized.
Язык: Английский
Advancement in Synthetic Strategies of Phosphorus Heterocycles: Recent Progress from Synthesis to Emerging Class of Optoelectronic Materials
Deepika Thakur,
Sushmita Sushmita,
Shivam A. Meena
и другие.
The Chemical Record,
Год журнала:
2024,
Номер
24(8)
Опубликована: Авг. 1, 2024
Organophosphorus
heterocycles
have
long
been
acknowledged
for
their
significant
potential
across
diverse
fields,
including
catalysis,
material
science,
and
drug
development.
Incorporating
phosphorus
functionalities
into
organic
compounds
offers
a
means
to
effectively
tailor
medicinal
properties,
augment
biological
responses,
enhance
selectivity
bioavailability.
The
distinctive
physical
photoelectric
characteristics
of
phosphorus-containing
conjugated
garnered
considerable
interest
as
promising
materials
optoelectronics.
These
find
extensive
utility
in
various
applications
such
light-emitting
diodes,
photovoltaic
cells,
phosphole-based
fluorophores,
semiconductors.
Язык: Английский
Recent Advances in Visible Light Induced Radical 1,2-Functionalization of Alkynes
Kangkui Li,
Xianyang Long,
Yue Huang
и другие.
Acta Chimica Sinica,
Год журнала:
2024,
Номер
82(6), С. 658 - 658
Опубликована: Янв. 1, 2024
Язык: Английский
Advanced green synthesis: Solvent-free and catalyst-free reaction
Green Synthesis and Catalysis,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 1, 2024
Язык: Английский
Research on Alkyne Carbon Cyclization Reactions Based on Intermolecular Radical Addition/Translocation/Cyclization (RATC) Strategy
Journal of Organic Chemistry Research,
Год журнала:
2025,
Номер
13(01), С. 1 - 12
Опубликована: Янв. 1, 2025
Язык: Английский
Photocatalytic Cyclization of 2-Phosphinobiaryls to Trivalent Dibenzophospholes
ACS Catalysis,
Год журнала:
2025,
Номер
unknown, С. 6514 - 6524
Опубликована: Апрель 7, 2025
Язык: Английский
Photocatalytic Phosphine-Mediated Deoxygenative [3 + 2] Cycloaddition of α,β-Unsaturated Carbonyls and Alkenes
Journal of the American Chemical Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 22, 2025
Tertiary
phosphine
is
a
powerful
nucleophile
that
enables
numerous
synthetically
important
reactions.
However,
the
exclusive
reliance
on
two-electron
pathway
has
restricted
development
of
chemistry.
We
report
here
visible
light
photocatalytic
phosphine-mediated
deoxygenative
[3
+
2]
cycloaddition
α,β-unsaturated
carbonyls
and
activated
alkenes,
providing
facile
access
to
polysubstituted
cyclopentenes
from
readily
accessible
starting
materials
in
promising
yields
with
good
substrate
scope.
Mechanistic
investigations
corroborate
transient
involvement
radical
cation
consequent
α-addition
(α
electron-withdrawing
groups)
C-C
double
bonds
due
inherent
electrophilicity
cation,
as
opposed
traditional
nucleophilic
β-addition
phosphine.
The
ensuing
single
electron
transfer
reduction,
Michael
addition,
1,4-proton
cascade
furnish
phosphorus
ylide,
which
undergoes
an
intramolecular
Wittig
reaction
finish
construction
cyclopentenes.
This
work
demonstrates
tertiary
can
serve
convenient
reagent
for
carbonyl
deoxygenation
act
traceless
directing
group
controllable
cross-coupling
two
distinct
new
avenues
expand
frontiers
chemistry
synthetic
Язык: Английский
Cobalt- or rhodium-catalyzed synthesis of 1,2-dihydrophosphete oxides via C–H activation and formal phosphoryl migration
Chemical Science,
Год журнала:
2024,
Номер
15(16), С. 6012 - 6021
Опубликована: Янв. 1, 2024
A
highly
stereo-
and
chemoselective
intermolecular
coupling
of
diverse
heterocycles
with
dialkynylphosphine
oxides
has
been
realized
Язык: Английский
Photocatalytic [3+2] Cycloaddition of Alkyl/aryl Iodides and Internal Alkynes by Merging Halogen and Hydrogen Atom Transfer
Chinese Journal of Chemistry,
Год журнала:
2024,
Номер
42(19), С. 2329 - 2334
Опубликована: Май 22, 2024
Comprehensive
Summary
A
visible
light
photocatalytic
[3+2]
cycloaddition
of
alkynes
with
readily
accessible
organic
iodides
as
the
C3
synthon
is
developed
herein.
By
merging
halogen
atom
transfer
(XAT)
and
hydrogen
(HAT),
alkyl/aryl
serve
a
formal
diradical
precursor
add
across
C‐C
triple
bonds
to
deliver
number
functionalized
cyclopentanes
in
moderate
high
yields
exceptional
regio‐
diastereoselectivity.
reductive
radical‐polar
crossover
mechanism,
involving
cascade
XAT,
radical
addition,
1,5‐HAT,
polar
effect‐promoted
5‐endo
annulation,
single
electron
(SET)
reduction,
protonation,
may
account
for
this
unprecedented
dehalogenative
cycloaddition.
This
work
not
only
expands
repertoire
traditional
RATC
methodology,
but
also
provides
robust
platform
expedient
assembly
cyclopentanes,
valuable
structural
motif
realms
medicinal
chemistry
material
sciences.
Язык: Английский