Next-generation approaches to understand and combat the antibiotic resistome

Nature Reviews Microbiology, Год журнала: 2017, Номер 15(7), С. 422 - 434

Опубликована: Апрель 10, 2017

Язык: Английский

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The reconstruction of 2,631 draft metagenome-assembled genomes from the global oceans

Scientific Data, Год журнала: 2018, Номер 5(1)

Опубликована: Янв. 16, 2018

Abstract Microorganisms play a crucial role in mediating global biogeochemical cycles the marine environment. By reconstructing genomes of environmental organisms through metagenomics, researchers are able to study metabolic potential Bacteria and Archaea that resistant isolation laboratory. Utilizing large metagenomic dataset generated from 234 samples collected during Tara Oceans circumnavigation expedition, we were assemble 102 billion paired-end reads into 562 million contigs, which turn co-assembled consolidated 7.2 contigs ≥2 kb length. Approximately 1 these binned reconstruct draft genomes. In total, 2,631 with an estimated completion ≥50% (1,491 >70% complete; 603 >90% complete). A majority manually assigned phylogeny based on sets concatenated phylogenetic marker genes and/or 16S rRNA gene sequences. The now publically available for research community at-large.

Язык: Английский

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Common principles and best practices for engineering microbiomes

Nature Reviews Microbiology, Год журнала: 2019, Номер 17(12), С. 725 - 741

Опубликована: Сен. 23, 2019

Язык: Английский

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CheckM2: a rapid, scalable and accurate tool for assessing microbial genome quality using machine learning

Nature Methods, Год журнала: 2023, Номер 20(8), С. 1203 - 1212

Опубликована: Июль 27, 2023

Язык: Английский

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Genome-centric view of carbon processing in thawing permafrost

Nature, Год журнала: 2018, Номер 560(7716), С. 49 - 54

Опубликована: Июль 11, 2018

Язык: Английский

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