Next-generation approaches to understand and combat the antibiotic resistome

Nature Reviews Microbiology, Journal Year: 2017, Volume and Issue: 15(7), P. 422 - 434

Published: April 10, 2017

Language: Английский

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The reconstruction of 2,631 draft metagenome-assembled genomes from the global oceans

Scientific Data, Journal Year: 2018, Volume and Issue: 5(1)

Published: Jan. 16, 2018

Abstract Microorganisms play a crucial role in mediating global biogeochemical cycles the marine environment. By reconstructing genomes of environmental organisms through metagenomics, researchers are able to study metabolic potential Bacteria and Archaea that resistant isolation laboratory. Utilizing large metagenomic dataset generated from 234 samples collected during Tara Oceans circumnavigation expedition, we were assemble 102 billion paired-end reads into 562 million contigs, which turn co-assembled consolidated 7.2 contigs ≥2 kb length. Approximately 1 these binned reconstruct draft genomes. In total, 2,631 with an estimated completion ≥50% (1,491 >70% complete; 603 >90% complete). A majority manually assigned phylogeny based on sets concatenated phylogenetic marker genes and/or 16S rRNA gene sequences. The now publically available for research community at-large.

Language: Английский

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Common principles and best practices for engineering microbiomes

Nature Reviews Microbiology, Journal Year: 2019, Volume and Issue: 17(12), P. 725 - 741

Published: Sept. 23, 2019

Language: Английский

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CheckM2: a rapid, scalable and accurate tool for assessing microbial genome quality using machine learning

Nature Methods, Journal Year: 2023, Volume and Issue: 20(8), P. 1203 - 1212

Published: July 27, 2023

Language: Английский

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Genome-centric view of carbon processing in thawing permafrost

Nature, Journal Year: 2018, Volume and Issue: 560(7716), P. 49 - 54

Published: July 11, 2018

Language: Английский

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