The
field
of
biomedical
design
and
manufacturing
has
been
rapidly
evolving,
with
implants
grafts
featuring
complex
3D
constraints
materials
distributions.
By
combining
a
new
coding-based
modeling
approach
high-throughput
volumetric
printing,
is
demonstrated
to
transform
the
way
shapes
are
designed
fabricated
for
applications.
Here,
an
algorithmic
voxel-based
used
that
can
generate
large
library
porous
structures,
auxetic
meshes
cylinders,
or
perfusable
constructs.
deploying
finite
cell
within
framework,
arrays
selected
designs
be
computationally
modeled.
Finally,
schemes
in
conjunction
approaches
multi-material
printing
based
on
thiol-ene
photoclick
chemistry
fabricate
heterogeneous
shapes.
Collectively,
design,
fabrication
techniques
toward
wide
spectrum
products
such
as
actuators,
grafts,
tissue
disease
models.
Nature Communications,
Год журнала:
2023,
Номер
14(1)
Опубликована: Июль 21, 2023
Volumetric
additive
manufacturing
techniques
are
a
promising
pathway
to
ultra-rapid
light-based
3D
fabrication.
Their
widespread
adoption,
however,
demands
significant
improvement
in
print
fidelity.
Currently,
volumetric
prints
suffer
from
systematic
undercuring
of
fine
features,
making
it
impossible
objects
containing
wide
range
feature
sizes,
precluding
effective
adoption
many
applications.
Here,
we
uncover
the
reason
for
this
limitation:
light
dose
spread
resin
due
chemical
diffusion
and
optical
blurring,
which
becomes
features
⪅0.5
mm.
We
develop
model
that
quantitatively
predicts
variation
time
with
size
demonstrate
deconvolution
method
correct
error.
This
enables
previously
beyond
capabilities
manufacturing,
such
as
complex
gyroid
structure
variable
thickness
fine-toothed
gear.
These
results
position
mature
printing
method,
all
but
eliminating
gap
industry-standard
Advanced Materials,
Год журнала:
2023,
Номер
36(4)
Опубликована: Авг. 11, 2023
Additive
manufacturing
techniques
continue
to
improve
in
resolution,
geometrical
freedom,
and
production
rates,
expanding
their
application
range
research
industry.
Most
established
techniques,
however,
are
based
on
layer-by-layer
polymerization
processes,
leading
an
inherent
trade-off
between
resolution
printing
speed.
Volumetric
3D
enables
the
of
freely
defined
volumes
allowing
fabrication
complex
geometries
at
drastically
increased
rates
high
resolutions,
marking
next
chapter
light-based
additive
manufacturing.
This
work
advances
volumetric
technique
xolography
a
continuous
process.
Dual-color
photopolymerization
is
performed
continuously
flowing
resin,
inside
tailored
flow
cell.
Supported
by
simulations,
profile
area
flattened,
resin
velocities
cell
walls
minimize
unwanted
via
laser
sheet-induced
curing.
Various
objects
printed
true
shape
with
smooth
surfaces.
Parallel
object
paves
way
for
up-scaling
production,
currently
reaching
up
1.75
mm
Biofabrication,
Год журнала:
2023,
Номер
16(1), С. 012004 - 012004
Опубликована: Ноя. 3, 2023
The
three-dimensional
(3D)
bioprinting
technologies
are
suitable
for
biomedical
applications
owing
to
their
ability
manufacture
complex
and
high-precision
tissue
constructs.
However,
the
slow
printing
speed
of
current
layer-by-layer
(bio)printing
modality
is
major
limitation
in
biofabrication
field.
To
overcome
this
issue,
volumetric
(VBP)
developed.
VBP
changes
layer-wise
operation
conventional
devices,
permitting
creation
geometrically
complex,
centimeter-scale
constructs
tens
seconds.
next
step
onward
from
sequential
methods,
opening
new
avenues
fast
additive
manufacturing
fields
engineering,
regenerative
medicine,
personalized
drug
testing,
soft
robotics,
etc.
Therefore,
review
introduces
principles
hardware
designs
VBP-based
techniques;
then
focuses
on
recent
advances
(bio)inks
applications.
Lastly,
limitations
discussed
together
with
future
direction
research.
Abstract
High
spatial‐resolution
detection
is
essential
for
biomedical
applications
and
human‐machine
interaction.
However,
as
the
sensor
array
density
increases,
miniaturization
will
lead
to
interference
between
adjacent
units
deterioration
in
sensing
performance.
Here,
inspired
by
cochlea's
structure,
a
high‐density
flexible
pressure
featuring
with
suspended
membrane
sensitivity‐enhanced
customized
channels
presented
crosstalk‐free
high‐resolution
detection.
By
imitating
basilar
attached
spiral
ligaments,
fixed
onto
high‐stiffness
substrate
cavities,
forming
stable
braced
isolation
provide
an
excellent
capability
(crosstalk
coefficient:
47.24
dB)
integration
(100
within
1
cm
2
).
Similar
opening
of
ion
hair
cells,
wedge‐type
expansion
embedded
cracks
introduced
stress
concentration
structures
enables
high
sensitivity
(0.19
kPa
−1
)
large
measuring
range
(400
kPa).
Finally,
it
demonstrates
promising
distributed
displays
condition
monitoring
medical‐surgical
intubation.
Nature,
Год журнала:
2024,
Номер
634(8036), С. 1096 - 1102
Опубликована: Окт. 30, 2024
Additive
manufacturing
is
an
expanding
multidisciplinary
field
encompassing
applications
including
medical
devices1,
aerospace
components2,
microfabrication
strategies3,4
and
artificial
organs5.
Among
additive
approaches,
light-based
printing
technologies,
two-photon
polymerization6,
projection
micro
stereolithography7,8
volumetric
printing9–14,
have
garnered
significant
attention
due
to
their
speed,
resolution
or
potential
for
biofabrication.
Here
we
introduce
dynamic
interface
printing,
a
new
3D
approach
that
leverages
acoustically
modulated,
constrained
air–liquid
boundary
rapidly
generate
centimetre-scale
structures
within
tens
of
seconds.
Unlike
this
process
eliminates
the
need
intricate
feedback
systems,
specialized
chemistry
complex
optics
while
maintaining
rapid
speeds.
We
demonstrate
versatility
technique
across
broad
array
materials
geometries,
those
would
be
impossible
print
with
conventional
layer-by-layer
methods.
In
doing
so,
fabrication
in
situ,
overprinting,
structural
parallelization
biofabrication
utility.
Moreover,
show
formation
surface
waves
at
enables
enhanced
mass
transport,
improves
material
flexibility
permits
particle
patterning.
We,
therefore,
anticipate
will
invaluable
where
high-resolution,
scalable
throughput
biocompatible
required.
Dynamic
form
Chemical Reviews,
Год журнала:
2024,
Номер
124(14), С. 8787 - 8822
Опубликована: Июль 5, 2024
Harnessing
light
for
cross-linking
of
photoresponsive
materials
has
revolutionized
the
field
3D
printing.
A
wide
variety
techniques
leveraging
broad-spectrum
shaping
have
been
introduced
as
a
way
to
achieve
fast
and
high-resolution
printing,
with
applications
ranging
from
simple
prototypes
biomimetic
engineered
tissues
regenerative
medicine.
Conventional
light-based
printing
use
material
in
layer-by-layer
fashion
produce
complex
parts.
Only
recently,
new
emerged
which
deploy
multidirection,
tomographic,
light-sheet
or
filamented
image
projections
deep
into
volume
resin-filled
vat
photoinitiation
cross-linking.
These
Deep
Vat
(DVP)
approaches
alleviate
need
layer-wise
enable
unprecedented
fabrication
speeds
(within
few
seconds)
high
resolution
(>10
μm).
Here,
we
elucidate
physics
chemistry
these
processes,
their
commonalities
differences,
well
emerging
biomedical
non-biomedical
fields.
Importantly,
highlight
limitations,
future
scope
research
that
will
improve
scalability
applicability
DVP
engineering
medicine
applications.
ACS Biomaterials Science & Engineering,
Год журнала:
2025,
Номер
11(1), С. 156 - 181
Опубликована: Янв. 2, 2025
Volumetric
additive
manufacturing
(VAM)
is
revolutionizing
the
field
of
cell
printing
by
enabling
rapid
creation
complex
three-dimensional
cellular
structures
that
mimic
natural
tissues.
This
paper
explores
advantages
and
limitations
various
VAM
techniques,
such
as
holographic
lithography,
digital
light
processing,
volumetric
projection,
while
addressing
their
suitability
across
diverse
industrial
applications.
Despite
significant
potential
VAM,
challenges
related
to
regulatory
compliance
scalability
persist,
particularly
in
context
bioprinted
In
India,
lack
clear
guidelines
intellectual
property
protections
poses
additional
hurdles
for
companies
seeking
navigate
evolving
landscape
bioprinting.
study
emphasizes
importance
collaboration
among
industry
stakeholders,
agencies,
academic
institutions
establish
tailored
frameworks
promote
innovation
ensuring
safety
efficacy.
By
bridging
gap
between
technological
advancement
oversight,
can
unlock
new
opportunities
regenerative
medicine
tissue
engineering,
transforming
patient
care
therapeutic
outcomes.
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 17, 2025
Abstract
Multi‐material
printing
has
experienced
critical
advances
in
recent
years,
yet
material
property
differentiation
capabilities
remain
limited
both
with
regard
to
the
accessible
properties
–
typically
hard
versus
soft
and
achievable
magnitude
of
differentiation.
To
enhance
multi‐material
capabilities,
precise
photochemical
control
during
3D
is
essential.
Wavelength‐differentiation
a
particularly
intriguing
concept
challenging
implement.
Notably,
dual‐wavelength
fabricate
sections
within
one
object
emerged,
where
curing
process
insensitive
visible
light,
while
UV
irradiation
inevitably
activates
entire
resin,
limiting
true
spatio‐temporal
properties.
Until
now,
pathway‐independent
wavelength‐orthogonal
not
been
realized,
each
wavelength
exclusively
triggers
only
two
possible
reactions,
independent
order
which
wavelengths
are
applied.
Herein,
multi‐wavelength
technique
introduced
employing
tunable
laser
monochromatically
deliver
light
platform
loaded
fully
resin.
Guided
by
action
plots,
distinct
highly
selective
toward
specific
photocycloaddtion
reaction
utilized
generate
networks
photoresin.
Ultimately,
together
technique,
this
orthogonally
addressable
photoresin
allows
fabricating
objects
degradable
non‐degradable
properties,
single
fabrication
step.
MRS Bulletin,
Год журнала:
2022,
Номер
47(6), С. 628 - 641
Опубликована: Июнь 1, 2022
Abstract
Three-dimensional
printing,
or
additive
manufacturing
(AM),
is
a
broad
term
for
wide
range
of
fabrication
methods
utilizing
materials
such
as
small-molecule,
polymer,
and
metal
feedstocks.
Each
method
requires
different
chemical,
physical,
engineering
needs
to
be
successful.
This
article
will
discuss
some
the
considerations
polymer-based
AM
methods.
Ultimately,
we
focus
on
chemistries
vat
photopolymerization,
in
which
light
used
cure
resin
from
liquid
solid,
provide
an
example
how
chemical
advancements
have
led
increased
speed,
resolution,
multimaterial
printing
capabilities
not
previously
possible.
Graphical
abstract
Journal of Manufacturing and Materials Processing,
Год журнала:
2023,
Номер
7(1), С. 35 - 35
Опубликована: Янв. 31, 2023
Significant
advances
have
been
made
in
recent
years
the
materials
development
of
liquid-based
4D
printing.
Nevertheless,
employing
additive
such
as
nanoparticles
for
enhancing
printability
and
shape
memory
characteristics
is
still
challenging.
Herein,
we
provide
an
overview
developments
printing
highlights
novel
4D-printable
polymeric
resins
their
nanocomposite
components.
Recent
manufacturing
technologies
that
utilise
liquid
resins,
stereolithography,
digital
light
processing,
material
jetting
direct
ink
writing,
are
considered
this
review.
The
effects
nanoparticle
inclusion
within
on
mechanical
3D-printed
components
comprehensively
discussed.
Employing
various
filler-modified
mixture
nanosilica,
nanoclay
nanographene,
well
fibrous
to
support
properties
3D
considered.
Overall,
review
paper
provides
outline
4D-printed
nanocomposites
terms
cutting-edge
research,
including
properties.