Recent advances in the synthesis of pyrroles by multicomponent reactions

Chemical Society Reviews, Год журнала: 2014, Номер 43(13), С. 4633 - 4657

Опубликована: Янв. 1, 2014

Efficient and environmentally attractive access to pyrroles can be gained by use of multicomponent reactions.

Язык: Английский

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Recent advances in the application of deep eutectic solvents as sustainable media as well as catalysts in organic reactions

RSC Advances, Год журнала: 2015, Номер 5(60), С. 48675 - 48704

Опубликована: Янв. 1, 2015

This review highlights the recent advances using deep eutectic solvents (DESs), ionic liquids (DEILs), low-melting mixtures (LMMs) or low transition temperature (LTTMs) as green media well catalysts in organic reactions.

Язык: Английский

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Cobalt ferrite nanoparticles (CoFe₂O₄ MNPs) as catalyst and support: magnetically recoverable nanocatalysts in organic synthesis

Nanotechnology Reviews, Год журнала: 2017, Номер 7(1), С. 43 - 68

Опубликована: Окт. 10, 2017

Abstract Recovery and reusability of catalysts is an important aspect in modern catalysis research especially organic synthesis. Compared to the conventional separation, magnetic separation has emerged as a robust, highly efficient, easy rapid technique for products catalysts. Cobalt ferrite nanoparticles are well-known material, recognized CoFe 2 O 4 MNPs, can be used both catalyst versatile support functionalization metals, organocatalysts. In recent times, clearly experienced renaissance area utility cobalt (CoFe MNPs) nanocatalysts based on their ability recovery reusability; activity these MNPs was investigated category reactions. this review, fabrication, characterization, application (CF-MNPs) reactions have well summarized.

Язык: Английский

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Deep eutectic solvent based on choline chloride and malonic acid as an efficient and reusable catalytic system for one-pot synthesis of functionalized pyrroles

RSC Advances, Год журнала: 2014, Номер 5(10), С. 7720 - 7728

Опубликована: Дек. 22, 2014

Deep eutectic solvent (DES) based on choline chloride and malonic acid was applied as catalyst reaction medium for synthesis of pyrroles by one-pot, four-component amines, aldehydes, 1,3-dicarbonyl compounds nitromethane.

Язык: Английский

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Active methylenes in the synthesis of a pyrrole motif: an imperative structural unit of pharmaceuticals, natural products and optoelectronic materials

RSC Advances, Год журнала: 2016, Номер 6(43), С. 37039 - 37066

Опубликована: Янв. 1, 2016

Pyrrole is one of the most important azaheterocycles, due to its wide range applications in pharmaceuticals and optoelectronic materials, coupled with utility as an intermediate natural products.

Язык: Английский

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The synthesis of pyrroles via acceptorless dehydrogenative condensation of secondary alcohols and 1,2-amino alcohols mediated by a robust and reusable catalyst based on nanometer-sized iridium particles

Catalysis Science & Technology, Год журнала: 2014, Номер 4(12), С. 4188 - 4192

Опубликована: Авг. 26, 2014

Pyrroles are important compounds with several applications in medicine and material science. They can be synthesized sustainably from secondary alcohols amino alcohols. Hydrogen water liberated the course of this reaction. Here, we present that sustainable catalytic pyrrole synthesis mediated efficiently by a novel iridium nanoparticle catalyst. The catalyst starts molecular precursors, an N-ligand stabilized Ir complex commercially available polysilazane. generation nanometer-sized particles was achieved (due to presence N atoms support). robust nature support allows reuse scope reaction verified 23 derivatives (up 93% isolated yield). Thus, attractive functional group tolerance (e.g. amines olefins) could observed. Commercially heterogeneous catalysts inefficient extremely limited terms reusability.

Язык: Английский

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Heterogeneous Fe-MIL-101 catalysts for efficient one-pot four-component coupling synthesis of highly substituted pyrroles

New Journal of Chemistry, Год журнала: 2015, Номер 39(6), С. 4919 - 4923

Опубликована: Янв. 1, 2015

Fe-MIL-101 as efficient heterogeneous catalysts for four-component coupling synthesis of highly substituted pyrroles.

Язык: Английский

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Nano CoFe₂O₄supported antimony(iii) as an efficient and recyclable catalyst for one-pot three-component synthesis of multisubstituted pyrroles

RSC Advances, Год журнала: 2014, Номер 4(25), С. 12929 - 12943

Опубликована: Янв. 1, 2014

A novel magnetic nano-CoFe₂O₄supported Sb ([CoFe₂O₄@SiO₂-DABCO-Sb]) was successfully constructed and identified as an efficient catalyst for synthesis of multisubstituted pyrrolesviaone-pot three-component reaction amines, nitroolefin 1,3-dicarbonyl compounds.

Язык: Английский

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Optimization of biodiesel production from waste cooking oil using Fe-Montmorillonite K10 by response surface methodology

Renewable Energy, Год журнала: 2020, Номер 157, С. 164 - 172

Опубликована: Май 7, 2020

Язык: Английский

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Discovery of Quinazolin-4(3H)-ones as NLRP3 Inflammasome Inhibitors: Computational Design, Metal-Free Synthesis, and in Vitro Biological Evaluation

The Journal of Organic Chemistry, Год журнала: 2019, Номер 84(9), С. 5129 - 5140

Опубликована: Март 21, 2019

NLRP3 inflammasome is an important therapeutic target for a number of human diseases. Herein, computationally designed series quinazolin-4(3H)-ones were synthesized using iodine-catalyzed coupling arylalkynes (or styrenes) with O-aminobenzamides. The key event in this transformation involves the oxidative cleavage C–C triple/double bond and release formaldehyde. reaction relies on C–N formation along under metal-free conditions. nitro-substituted quinazolin-4(3H)-one 2k inhibited (IC50 5 μM) via suppression IL-1β from ATP-stimulated J774A.1 cells.

Язык: Английский

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