Advanced Synthesis & Catalysis,
Год журнала:
2019,
Номер
361(8), С. 1808 - 1814
Опубликована: Март 8, 2019
Abstract
A
simple
and
catalyst‐free
strategy
was
developed
for
the
synthesis
of
unsymmetrical
thiosulfonates
using
readily
available
DABCO⋅(SO
2
)
as
a
solid
bench‐stable
sulfur
dioxide
surrogate.
The
corresponding
were
obtained
through
radical
pathway
with
good
functional
group
tolerance.
This
offers
promising
method
construction
diverse
useful
in
field
synthetic
pharmaceutical
chemistry
extends
number
still
limited
fixation
strategies.
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image
Chemical Communications,
Год журнала:
2019,
Номер
55(38), С. 5408 - 5419
Опубликована: Янв. 1, 2019
In
this
review,
the
recent
advances
of
application
1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene
(4CzIPN)
as
a
photoredox
catalyst
in
past
three
years
(2016–2018)
for
various
organic
reactions
are
summarized.
Chemical Society Reviews,
Год журнала:
2020,
Номер
50(2), С. 766 - 897
Опубликована: Дек. 22, 2020
Recent
developments
and
future
prospects
of
visible-light
photocatalysis
in
the
late-stage
functionalization
pharmaceuticals
natural
bioactive
compounds.
Chemical Society Reviews,
Год журнала:
2022,
Номер
51(6), С. 2313 - 2382
Опубликована: Янв. 1, 2022
Visible-light
photoredox
catalysis
has
been
regarded
as
an
extremely
powerful
tool
in
organic
chemistry,
bringing
the
spotlight
back
to
radical
processes.
The
versatility
of
photocatalyzed
reactions
already
demonstrated
be
effective
providing
alternative
routes
for
cross-coupling
well
multicomponent
reactions.
photocatalyst
allows
generation
high-energy
intermediates
through
light
irradiation
rather
than
using
highly
reactive
reagents
or
harsh
reaction
conditions.
In
a
similar
vein,
electrochemistry
experienced
fruitful
renaissance
generating
without
need
any
catalyst.
Such
milder
approaches
pose
basis
toward
higher
selectivity
and
broader
applicability.
electrochemical
reactions,
species
acts
starter
cascade
events.
This
diverse
reactivity
use
is
usually
not
covered
by
classical
methods.
Owing
availability
cheaper
more
standardized
photo-
reactors,
easily
scalable
flow-setups,
it
surprising
that
these
two
fields
have
become
areas
increased
research
interest.
Keeping
view,
this
review
aimed
at
overview
synthetic
design
MCRs
involving
and/or
activation
crucial
step
with
particular
focus
on
choice
difunctionalized
reagent.
Advanced Synthesis & Catalysis,
Год журнала:
2020,
Номер
362(21), С. 4446 - 4461
Опубликована: Июль 15, 2020
Abstract
The
field
in
dearomatization
of
aromatic
compounds
for
the
construction
spirocycle
has
been
developed
rapidly
over
last
two
decades
and
it
provides
alternative
synthetic
method
without
using
extra
stoichiometric
amounts
chemical
oxidants
or
reductants.
In
addition,
radical
cascade
reactions
alkenes
alkynes
that
produce
multiple
bonds
one‐step
are
significant
direct
efficient
building
complex
molecules.
By
combining
these
concepts,
opens
a
new
powerful
avenue
accessing
These
have
well
explored
past
decade.
As
result,
we
summarize
recent
eventful
advances
this
growing
area
as
review,
which
typical
examples
listed
mechanism
also
discussed.
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image
ACS Catalysis,
Год журнала:
2021,
Номер
11(12), С. 7513 - 7551
Опубликована: Июнь 9, 2021
Catalytic
functionalization
of
alkynes
with
organoboron
reagents
provides
a
straightforward
access
to
stereochemically
defined
multisubstituted
alkenes,
which
are
structural
motifs
commonly
found
in
bioactive
compounds
and
organic
materials.
Recent
progress
has
substantially
broadened
the
scope
this
field
on
several
fronts.
Strategies
for
regioselectivity
control
1,2-migratory
insertion
across
unsymmetrical
internal
alkynes,
as
well
direct
products
anti-insertion
stereochemistry,
have
been
devised.
The
alkenyl-to-aryl
1,4-metal
migration
upon
metal
recently
exploited
powerful
cascade
sequences
leading
complex
polycyclic
scaffolds,
including
development
enantioselective
processes.
Elegant
enantiospecific
dynamic
kinetic
resolution
methods
developed
accessing
chiral
allenes
from
propargylic
alcohol
derivatives.
Mechanistic
manifolds
emerged
based
single-electron
transfer
(SET)
that
provided
fresh
impetus
alkyne
1,2-difunctionalization
complementary
stereoselectivity
processes
relying
1,2-insertion
R–M
species.
Herein,
we
discuss
most
recent
advances
transition-metal-catalyzed
using
reagents,
categorized
according
type
mechanistic
outcome.
Emphasis
is
placed
aspects,
synthetic
utility,
limitations,
challenges
future
research.
Chemical Communications,
Год журнала:
2019,
Номер
55(19), С. 2861 - 2864
Опубликована: Янв. 1, 2019
A
simple
and
efficient
decarboxylative
radical
addition/cyclization
strategy
was
developed,
by
which
a
wide
range
of
benzimidazo[2,1-a]isoquinoline-6(5H)-ones
were
prepared
in
one-pot
via
reaction
functionalized
2-arylbenzoimidazoles
carboxylic
acids
the
presence
K2S2O8/AgNO3
under
mild
conditions.
Organic & Biomolecular Chemistry,
Год журнала:
2018,
Номер
16(46), С. 9064 - 9068
Опубликована: Янв. 1, 2018
A
simple
and
practical
method
for
the
synthesis
of
alkenyl
dithiocyanates
diselenocyanates
has
been
developed
via
stereoselective
difunctionalization
alkynes
with
NaSCN
or
KSeCN
at
room
temperature.
Through
this
methodology,
a
series
could
be
efficiently
conveniently
obtained
in
moderate
to
good
yields
under
mild
metal-free
conditions
by
use
oxone
PhI(OAc)2
as
oxidants.
Organic Chemistry Frontiers,
Год журнала:
2020,
Номер
8(3), С. 445 - 465
Опубликована: Окт. 26, 2020
The
application
of
the
cyano
group
as
a
radical
acceptor
in
cascade
reactions
for
construction
various
important
heterocycles
and
carbocycles
was
summarized.
Advanced Synthesis & Catalysis,
Год журнала:
2019,
Номер
361(22), С. 5176 - 5181
Опубликована: Сен. 26, 2019
Abstract
A
metal‐free
visible‐light‐induced
cyclization
procedure
was
developed
for
the
rapid
synthesis
of
perfluoroalkyl‐substituted
benzimidazo[2,1‐
a
]isoquinolin‐6(5
H
)‐ones
and
indolo[2,1‐
under
mild
reaction
conditions.
In
this
procedure,
formation
electron‐donor‐acceptor
(EDA)
complex
is
critical
visible‐light
promoted
process
to
avoid
utilization
external
photocatalysts.
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image
