Advanced Synthesis & Catalysis,
Год журнала:
2019,
Номер
362(3), С. 688 - 694
Опубликована: Дек. 5, 2019
Abstract
A
Mn(III)‐mediated
radical
cyclization
reaction
of
o
‐vinylaryl
isocyanides
and
arylboronic
acids
or
diphenylphosphine
oxides
to
access
various
2‐functionalized
quinolines
under
mild
conditions
was
developed.
With
the
introduction
stabilizing
substituents
(e.
g.
aryl
methyl
group)
on
vinyl
group,
this
provides
a
regiospecific
6‐
endo
‐trig
isocyanides,
giving
number
structurally
unique
biologically
potential
quinoline
derivatives.
magnified
image
Chemical Society Reviews,
Год журнала:
2022,
Номер
51(11), С. 4386 - 4464
Опубликована: Янв. 1, 2022
The
emerging
field
of
organometallic
catalysis
has
shifted
towards
research
on
Earth-abundant
transition
metals
due
to
their
ready
availability,
economic
advantage,
and
novel
properties.
In
this
case,
manganese,
the
third
most
abundant
transition-metal
in
Earth's
crust,
emerged
as
one
leading
competitors.
Accordingly,
a
large
number
molecularly-defined
Mn-complexes
been
synthesized
employed
for
hydrogenation,
dehydrogenation,
hydroelementation
reactions.
regard,
catalyst
design
is
based
three
pillars,
namely,
metal-ligand
bifunctionality,
ligand
hemilability,
redox
activity.
Indeed,
developed
catalysts
not
only
differ
chelating
atoms
they
possess
but
also
working
principles,
thereby
different
turnover
numbers
product
molecules.
Hence,
critical
assessment
molecularly
defined
manganese
terms
atoms,
reaction
conditions,
mechanistic
pathway,
significant.
Herein,
we
analyze
complexes
catalytic
activity,
versatility
allow
multiple
transformations
routes
convert
substrates
target
This
article
will
be
helpful
get
significant
insight
into
design,
aiding
design.
Organic Chemistry Frontiers,
Год журнала:
2021,
Номер
8(11), С. 2673 - 2709
Опубликована: Янв. 1, 2021
In
this
review,
we
have
summarized
various
aspects
of
homogeneous
and
heterogeneously
catalyzed
recent
advancements
in
the
synthesis
heterocycles
following
ADC
approach.
Coordination Chemistry Reviews,
Год журнала:
2021,
Номер
443, С. 213967 - 213967
Опубликована: Май 24, 2021
Catalytic
dehydrogenation
of
alcohols
represents
an
attractive
approach
for
future
applications
as
hydrogen
storage
systems
and
clean
synthesis
fine
chemicals.
Herein,
overview
recent
progress
in
homogeneously
catalyzed
acceptorless
alcohol
is
presented.
In
Nature,
efficiently
by
multiple
metalloenzymes
where
a
non-noble
metal–ligand
interplay
key
to
activate
transform
substrate.
We
highlight
the
introduction
multifunctional
cooperative
ligands
coordination
sphere
metal
center
order
improve
catalytic
activity
under
photochemical,
electrochemical
or
thermal
conditions.
Moreover,
cooperativity
crucial
easy
transition
first
row
based
catalysis,
we
have
seen
years.
Green Chemistry,
Год журнала:
2019,
Номер
21(8), С. 1999 - 2004
Опубликована: Янв. 1, 2019
Herein,
an
efficient
methodology
for
the
synthesis
of
a
diverse
class
N-heterocyclic
moieties,
such
as
quinoxalines,
benzimidazoles
and
quinazolines,
was
developed
in
water
using
bio-renewable
alcohols.
The
quinoxalines
were
successfully
synthesized
from
wide
range
diamines
nitroamines
with
diols
air.
Interestingly,
quinazolines
excellent
isolated
yields
without
any
external
base.
Finally,
preparative
scale
various
N-heterocycles
pharmaceutically
active
established
practicability
this
protocol.
For
iridium
system,
metal–ligand
cooperative
mechanism
proposed
based
on
kinetic
DFT
studies.
The Journal of Organic Chemistry,
Год журнала:
2019,
Номер
84(5), С. 2626 - 2641
Опубликована: Янв. 28, 2019
Simple,
straightforward,
and
atom
economic
methods
for
the
synthesis
of
quinolines,
2-aminoquinolines,
quinazolines
via
biomimetic
dehydrogenative
condensation/coupling
reactions,
catalyzed
by
well-defined
inexpensive
easy
to
prepare
singlet
diradical
Ni(II)-catalysts
featuring
two
antiferromagnetically
coupled
diamine
type
ligands
are
described.
Various
polysubstituted
were
synthesized
in
moderate
good
yields
from
different
low-cost
readily
accessible
starting
materials.
Several
control
experiments
carried
out
get
insight
into
reaction
mechanism
which
shows
that
nickel
coordinated
participate
a
synergistic
way
during
dehydrogenation
alcohols.
Organic Letters,
Год журнала:
2019,
Номер
21(9), С. 3223 - 3227
Опубликована: Апрель 22, 2019
A
sustainable
synthesis
of
quinazoline
and
2-aminoquinoline
via
acceptorless
dehydrogenative
annulation
is
presented.
The
reaction
catalyzed
by
earth-abundant
well-defined
manganese
complexes
bearing
NNS
ligands.
Furthermore,
a
one-pot
synthetic
strategy
for
the
2-alkylaminoquinolines
through
sequential
N-alkylation
has
also
been
demonstrated.
The Journal of Organic Chemistry,
Год журнала:
2019,
Номер
84(16), С. 10160 - 10171
Опубликована: Июль 22, 2019
A
simple
metal–ligand
cooperative
approach
for
the
dehydrogenative
functionalization
of
alcohols
to
various
substituted
quinolines
and
quinazolin-4(3H)-ones
under
relatively
mild
reaction
conditions
(≤90
°C)
is
reported.
Simple
easy-to-prepare
air-stable
Cu(II)
complexes
featuring
redox-active
azo-aromatic
scaffolds,
2-arylazo-(1,10-phenanthroline)
(L1,2),
are
used
as
catalyst.
wide
variety
were
synthesized
in
moderate
good
isolated
yields
via
coupling
reactions
inexpensive
easily
available
starting
materials
aerobic
conditions.
few
control
experiments
deuterium
labeling
studies
carried
out
understand
mechanism
reactions,
which
indicate
that
both
copper
coordinated
ligand
participate
a
manner
during
catalytic
cycle.
