Mn(III)‐Mediated Regioselective 6‐endo‐trig Radical Cyclization of o‐Vinylaryl Isocyanides to Access 2‐Functionalized Quinolines DOI
Yan Liu, Shijun Li, Xiaolan Chen

и другие.

Advanced Synthesis & Catalysis, Год журнала: 2019, Номер 362(3), С. 688 - 694

Опубликована: Дек. 5, 2019

Abstract A Mn(III)‐mediated radical cyclization reaction of o ‐vinylaryl isocyanides and arylboronic acids or diphenylphosphine oxides to access various 2‐functionalized quinolines under mild conditions was developed. With the introduction stabilizing substituents (e. g. aryl methyl group) on vinyl group, this provides a regiospecific 6‐ endo ‐trig isocyanides, giving number structurally unique biologically potential quinoline derivatives. magnified image

Язык: Английский

Nanoscale covalent organic frameworks: from controlled synthesis to cancer therapy DOI

Xuelu He,

Zhenqi Jiang, Ozioma Udochukwu Akakuru

и другие.

Chemical Communications, Год журнала: 2021, Номер 57(93), С. 12417 - 12435

Опубликована: Янв. 1, 2021

The controlled synthesis methods and the applications of nanoscale covalent organic frameworks in cancer therapy are summarized this feature article.

Язык: Английский

Процитировано

237

Homogeneous manganese-catalyzed hydrogenation and dehydrogenation reactions DOI Creative Commons
Yujie Wang, Mingyang Wang, Yibiao Li

и другие.

Chem, Год журнала: 2020, Номер 7(5), С. 1180 - 1223

Опубликована: Дек. 9, 2020

Язык: Английский

Процитировано

218

Manganese-catalyzed hydrogenation, dehydrogenation, and hydroelementation reactions DOI
Kuhali Das, Satyadeep Waiba, Akash Jana

и другие.

Chemical Society Reviews, Год журнала: 2022, Номер 51(11), С. 4386 - 4464

Опубликована: Янв. 1, 2022

The emerging field of organometallic catalysis has shifted towards research on Earth-abundant transition metals due to their ready availability, economic advantage, and novel properties. In this case, manganese, the third most abundant transition-metal in Earth's crust, emerged as one leading competitors. Accordingly, a large number molecularly-defined Mn-complexes been synthesized employed for hydrogenation, dehydrogenation, hydroelementation reactions. regard, catalyst design is based three pillars, namely, metal-ligand bifunctionality, ligand hemilability, redox activity. Indeed, developed catalysts not only differ chelating atoms they possess but also working principles, thereby different turnover numbers product molecules. Hence, critical assessment molecularly defined manganese terms atoms, reaction conditions, mechanistic pathway, significant. Herein, we analyze complexes catalytic activity, versatility allow multiple transformations routes convert substrates target This article will be helpful get significant insight into design, aiding design.

Язык: Английский

Процитировано

160

Recent advances in sustainable synthesis of N-heterocycles following acceptorless dehydrogenative coupling protocol using alcohols DOI
Milan Maji, Dibyajyoti Panja, Ishani Borthakur

и другие.

Organic Chemistry Frontiers, Год журнала: 2021, Номер 8(11), С. 2673 - 2709

Опубликована: Янв. 1, 2021

In this review, we have summarized various aspects of homogeneous and heterogeneously catalyzed recent advancements in the synthesis heterocycles following ADC approach.

Язык: Английский

Процитировано

146

Homogeneously catalyzed acceptorless dehydrogenation of alcohols: A progress report DOI Creative Commons
Mónica Trincado,

Jonas Bösken,

Hansjörg Grützmacher

и другие.

Coordination Chemistry Reviews, Год журнала: 2021, Номер 443, С. 213967 - 213967

Опубликована: Май 24, 2021

Catalytic dehydrogenation of alcohols represents an attractive approach for future applications as hydrogen storage systems and clean synthesis fine chemicals. Herein, overview recent progress in homogeneously catalyzed acceptorless alcohol is presented. In Nature, efficiently by multiple metalloenzymes where a non-noble metal–ligand interplay key to activate transform substrate. We highlight the introduction multifunctional cooperative ligands coordination sphere metal center order improve catalytic activity under photochemical, electrochemical or thermal conditions. Moreover, cooperativity crucial easy transition first row based catalysis, we have seen years.

Язык: Английский

Процитировано

115

Transition metals-catalyzed amination of biomass feedstocks for sustainable construction of N-heterocycles DOI
Qiong Yan, Xu Wu, Hao Jiang

и другие.

Coordination Chemistry Reviews, Год журнала: 2023, Номер 502, С. 215622 - 215622

Опубликована: Дек. 26, 2023

Язык: Английский

Процитировано

79

Cooperative iridium complex-catalyzed synthesis of quinoxalines, benzimidazoles and quinazolines in water DOI
Kaushik Chakrabarti, Milan Maji, Sabuj Kundu

и другие.

Green Chemistry, Год журнала: 2019, Номер 21(8), С. 1999 - 2004

Опубликована: Янв. 1, 2019

Herein, an efficient methodology for the synthesis of a diverse class N-heterocyclic moieties, such as quinoxalines, benzimidazoles and quinazolines, was developed in water using bio-renewable alcohols. The quinoxalines were successfully synthesized from wide range diamines nitroamines with diols air. Interestingly, quinazolines excellent isolated yields without any external base. Finally, preparative scale various N-heterocycles pharmaceutically active established practicability this protocol. For iridium system, metal–ligand cooperative mechanism proposed based on kinetic DFT studies.

Язык: Английский

Процитировано

124

Dehydrogenative Synthesis of Quinolines, 2-Aminoquinolines, and Quinazolines Using Singlet Diradical Ni(II)-Catalysts DOI
Gargi Chakraborty, Rina Sikari, Siuli Das

и другие.

The Journal of Organic Chemistry, Год журнала: 2019, Номер 84(5), С. 2626 - 2641

Опубликована: Янв. 28, 2019

Simple, straightforward, and atom economic methods for the synthesis of quinolines, 2-aminoquinolines, quinazolines via biomimetic dehydrogenative condensation/coupling reactions, catalyzed by well-defined inexpensive easy to prepare singlet diradical Ni(II)-catalysts featuring two antiferromagnetically coupled diamine type ligands are described. Various polysubstituted were synthesized in moderate good yields from different low-cost readily accessible starting materials. Several control experiments carried out get insight into reaction mechanism which shows that nickel coordinated participate a synergistic way during dehydrogenation alcohols.

Язык: Английский

Процитировано

110

Sustainable Synthesis of Quinazoline and 2-Aminoquinoline via Dehydrogenative Coupling of 2-Aminobenzyl Alcohol and Nitrile Catalyzed by Phosphine-Free Manganese Pincer Complex DOI
Kalicharan Das, Avijit Mondal,

Debjyoti Pal

и другие.

Organic Letters, Год журнала: 2019, Номер 21(9), С. 3223 - 3227

Опубликована: Апрель 22, 2019

A sustainable synthesis of quinazoline and 2-aminoquinoline via acceptorless dehydrogenative annulation is presented. The reaction catalyzed by earth-abundant well-defined manganese complexes bearing NNS ligands. Furthermore, a one-pot synthetic strategy for the 2-alkylaminoquinolines through sequential N-alkylation has also been demonstrated.

Язык: Английский

Процитировано

109

Metal–Ligand Cooperative Approach To Achieve Dehydrogenative Functionalization of Alcohols to Quinolines and Quinazolin-4(3H)-ones under Mild Aerobic Conditions DOI
Siuli Das, Suman Sinha,

Deepannita Samanta

и другие.

The Journal of Organic Chemistry, Год журнала: 2019, Номер 84(16), С. 10160 - 10171

Опубликована: Июль 22, 2019

A simple metal–ligand cooperative approach for the dehydrogenative functionalization of alcohols to various substituted quinolines and quinazolin-4(3H)-ones under relatively mild reaction conditions (≤90 °C) is reported. Simple easy-to-prepare air-stable Cu(II) complexes featuring redox-active azo-aromatic scaffolds, 2-arylazo-(1,10-phenanthroline) (L1,2), are used as catalyst. wide variety were synthesized in moderate good isolated yields via coupling reactions inexpensive easily available starting materials aerobic conditions. few control experiments deuterium labeling studies carried out understand mechanism reactions, which indicate that both copper coordinated ligand participate a manner during catalytic cycle.

Язык: Английский

Процитировано

98