Marine Drugs,
Год журнала:
2022,
Номер
20(4), С. 219 - 219
Опубликована: Март 22, 2022
Aquatic
invertebrates
are
a
major
source
of
biomaterials
and
bioactive
natural
products
that
can
find
applications
as
pharmaceutics,
nutraceutics,
cosmetics,
antibiotics,
antifouling
biomaterials.
Symbiotic
microorganisms
often
the
real
producers
many
secondary
metabolites
initially
isolated
from
marine
invertebrates;
however,
certain
number
them
actually
synthesized
by
macro-organisms.
In
this
review,
we
analysed
literature
years
2010–2019
on
(bioactive
molecules
biomaterials)
main
phyla
explored
so
far,
including
sponges,
cnidarians,
molluscs,
echinoderms
ascidians,
present
relevant
examples
interest
to
public
private
stakeholders.
We
also
describe
omics
tools
have
been
more
in
identifying
understanding
mechanisms
processes
underlying
biosynthesis
invertebrates.
Since
there
is
increasing
attention
finding
new
solutions
for
sustainable
large-scale
supply
compounds,
propose
possible
improvement
biodiscovery
pipeline
might
come
study
utilization
aquatic
invertebrate
stem
cells.
Nucleic Acids Research,
Год журнала:
2020,
Номер
49(D1), С. D509 - D515
Опубликована: Сен. 3, 2020
Marine
organisms
are
expected
to
be
an
important
source
of
inspiration
for
drug
discovery
after
terrestrial
plants
and
microorganisms.
Despite
the
remarkable
progress
in
field
marine
natural
products
(MNPs)
chemistry,
there
only
a
few
open
access
databases
dedicated
MNPs
research.
To
meet
growing
demand
mining
sharing
MNPs-related
data
resources,
we
developed
CMNPD,
comprehensive
database
based
on
manually
curated
data.
CMNPD
currently
contains
more
than
31
000
chemical
entities
with
various
physicochemical
pharmacokinetic
properties,
standardized
biological
activity
data,
systematic
taxonomy
geographical
distribution
organisms,
detailed
literature
citations.
It
is
integrated
platform
structure
dereplication
(assessment
novelty)
(marine)
products,
lead
compounds,
structure-activity
relationships
investigation
ecology.
Access
available
through
user-friendly
web
interface
at
https://www.cmnpd.org.
We
committed
providing
free
not
professional
researchers
but
also
broader
scientific
community
facilitate
from
ocean.
Journal of the American Chemical Society,
Год журнала:
2020,
Номер
142(9), С. 4114 - 4120
Опубликована: Фев. 11, 2020
This
report
describes
the
first
application
of
novel
NMR-based
machine
learning
tool
"Small
Molecule
Accurate
Recognition
Technology"
(SMART
2.0)
for
mixture
analysis
and
subsequent
accelerated
discovery
characterization
new
natural
products.
The
concept
was
applied
to
extract
a
filamentous
marine
cyanobacterium
known
be
prolific
producer
cytotoxic
environmental
Frontiers in Marine Science,
Год журнала:
2021,
Номер
8
Опубликована: Март 16, 2021
Coastal
countries
have
traditionally
relied
on
the
existing
marine
resources
(e.g.,
fishing,
food,
transport,
recreation,
and
tourism)
as
well
tried
to
support
new
economic
endeavors
(ocean
energy,
desalination
for
water
supply,
seabed
mining).
Modern
societies
lifestyle
resulted
in
an
increased
demand
dietary
diversity,
better
health
well-being,
biomedicines,
natural
cosmeceuticals,
environmental
conservation,
sustainable
energy
sources.
These
societal
needs
stimulated
interest
of
researchers
diverse
underexplored
environments
promising
sources
biomolecules
biomass,
they
are
addressed
by
emerging
field
(blue)
biotechnology.
Blue
biotechnology
provides
opportunities
a
wide
range
initiatives
commercial
pharmaceutical,
biomedical,
cosmetic,
nutraceutical,
feed,
agricultural,
related
industries.
This
article
synthesizes
essence,
opportunities,
responsibilities,
challenges
encountered
outlines
attainment
valorization
directly
derived
or
bio-inspired
products
from
organisms.
First,
concept
bioeconomy
is
introduced.
Then,
diversity
bioresources
including
overview
most
prominent
organisms
their
potential
biotechnological
uses
described.
followed
introducing
methodologies
exploration
these
main
use
case
scenarios
food
agronomy,
bioremediation
climate
change,
materials,
healthcare,
well-being
sectors.
The
key
aspects
fields
legislation
funding
provided,
with
emphasis
importance
communication
stakeholder
engagement
at
all
levels
development.
Finally,
vital
overarching
concepts,
such
quadruple
helix
Responsible
Research
Innovation
principle
highlighted
important
follow
within
field.
authors
this
review
collaborating
under
European
Commission-funded
Cooperation
Science
Technology
(COST)
Action
Ocean4Biotech
–
transdisciplinary
networking
platform
focus
study
state
affairs.
Natural Product Reports,
Год журнала:
2021,
Номер
39(3), С. 560 - 595
Опубликована: Окт. 9, 2021
The
mangrove
forests
are
a
complex
ecosystem
occurring
at
tropical
and
subtropical
intertidal
estuarine
zones
nourish
variety
of
fungi
that
produce
1387
secondary
metabolites
with
the
feature
source,
chemical
bioactive
diversity.
Russian Chemical Reviews,
Год журнала:
2021,
Номер
90(8), С. 895 - 1107
Опубликована: Апрель 20, 2021
The
interest
in
functional
supramolecular
systems
for
the
design
of
innovative
materials
and
technologies,
able
to
fundamentally
change
world,
is
growing
at
a
high
pace.
huge
array
publications
that
appeared
recent
years
global
literature
calls
systematization
structural
trends
inherent
formation
these
revealed
different
molecular
platforms
practically
useful
properties
they
exhibit.
attention
concentrated
on
topics
related
are
actively
explored
institutes
universities
Russia
last
10–15
years,
such
as
chemistry
host–guest
complexes,
crystal
engineering,
self-assembly
self-organization
solutions
interfaces,
biomimetics
machines
devices.
bibliography
includes
1714
references.
Fortschritte der Chemie Organischer Naturstoffe/Fortschritte der Chemie organischer Naturstoffe/Progress in the chemistry of organic natural products,
Год журнала:
2023,
Номер
unknown, С. 1 - 546
Food Production Processing and Nutrition,
Год журнала:
2023,
Номер
5(1)
Опубликована: Март 20, 2023
Abstract
Green
seaweed,
as
the
most
abundant
species
of
macroseaweeds,
is
an
important
marine
biological
resource.
It
a
rich
source
several
amino
acids,
fatty
and
dietary
fibers,
well
polysaccharides,
polyphenols,
pigments,
other
active
substances,
which
have
crucial
roles
in
various
processes
such
antioxidant
activity,
immunoregulation,
anti-inflammatory
response.
In
recent
years,
attention
to
resources
has
accelerated
exploration
utilization
green
seaweeds
for
greater
economic
value.
This
paper
elaborates
on
main
nutrients
substances
present
different
provides
review
their
activities
applications
high-value
utilization.
Graphical
abstract
