Visible
light
photocatalysis
is
now
recognized
as
a
cornerstone
to
drive
radical-based
transformations
with
good
efficiency
and
versatility
under
environmentally
friendly
reaction
conditions.
However,
the
high
reactivity
of
photogenerated
intermediates
imparts
several
challenges
for
controlling
stereoselectivity
process.
This
chapter
provides
an
overview
on
major
achievements
in
asymmetric
photoredox
catalysis.
Specifically,
two
types
enantioselective
photocatalytic
strategies
are
outlined.
The
first
one
involves
synergistic
merger
achiral
photocatalyst
chiral
co-catalyst.
part
divided
according
mode
catalysis
including
Lewis
base
catalysis,
hydrogen-bond
Brønsted
or
acid
catalyzes,
phase
transfer
second
strategy
deals
employment
single
organophotocatalyst
organometallic
photocatalyst.
European Journal of Organic Chemistry,
Год журнала:
2024,
Номер
27(10)
Опубликована: Янв. 9, 2024
Abstract
We
present
the
first
example
of
electrocatalytic
three‐component
annulation–iodosulfonylation
indole‐tethered
1,6‐enynes
with
arylsulfonyl
hydrazides
and
KI
for
accessing
various
iodosulfonated
pyrrolo[1,2‐
a
]indoles
in
moderate
to
excellent
yields
high
stereospecificity.
This
electrosynthesis
opens
new
avenues
construction
skeleton
good
functional
group
compatibility
under
environmentally
benign
condition.
Based
on
control
experiments
cyclic
voltammetry
data,
we
suggested
plausible
reaction
mechanism
which
included
anodic
oxidation,
homolysis
iodide,
radical
addition,
5
‐
exo
dig
cyclization,
coupling
or
nucleophilic
attack
iodide
ions
cascade.
Organic & Biomolecular Chemistry,
Год журнала:
2020,
Номер
18(23), С. 4298 - 4353
Опубликована: Янв. 1, 2020
This
review
summarizes
recent
developments
in
visible-light
enantioselective
photocatalysis
reactions,
which
provide
convenient
and
effective
tools
for
asymmetric
synthesis.
Advanced Synthesis & Catalysis,
Год журнала:
2020,
Номер
363(1), С. 62 - 119
Опубликована: Окт. 31, 2020
Abstract
The
use
of
clean
and
renewable
light
sources
is
increasingly
common
in
organic
synthesis
due
to
its
safety,
practicality
economy.
Recently,
photoredox
catalysis
has
shown
great
application
values
transformations
because
advantages
environmentally
friendly
abundant
resources.
Indoles
their
derivatives
(indolines,
oxindoles
isatins)
are
the
core
skeletons
some
important
compounds
widely‐present
various
natural
products
pharmaceuticals
with
different
biological
activities.
Therefore,
research
on
modification
indoles
particularly
for
chemists
pharmacologists.
This
review
summarizes
effects
photocatalysis
indole
recent
decades.
These
accomplished
by
using
metal
photocatalysts
(
i.
e
.,
Ir,
Ru,
Ni,
Cu,
Fe,
Au,
Rh,
TiO
2
,
etc.)
or
non‐metallic
Rose
Bengal,
Eosin
Y,
quinones,
naphthols,
N‐heterocyclic
carbenes,
carbazoles,
pyrylium
salts,
etc.),
without
need
photocatalysts.
detailed
mechanisms
these
photo‐catalyzed/promoted
reactions
also
highlighted
deeply.
And
we
hope
this
will
be
helpful
researchers
interested
promising
field
photocatalyzed
transformations.
magnified
image
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(4), С. 635 - 697
Опубликована: Янв. 13, 2024
Abstract
In
recent
years,
the
interest
to
develop
cyclizations
promoted
by
visible
light
has
been
gaining
a
lot
of
attention
due
its
sustainability
aspect.
this
review,
we
summarize
most
important
advances
in
period
describing
methods
used
generate
different
ring
sizes,
while
focusing
on
mechanistic
details
these
reactions.
Organic Letters,
Год журнала:
2020,
Номер
22(14), С. 5439 - 5445
Опубликована: Июнь 29, 2020
We
report
the
chiral
phosphoric
acid
catalyzed
formal
(3
+
2)
cycloaddition
of
3-substituted
1H-indoles
and
propargylic
alcohols
containing
a
functional
directing
group
(p-NHAc
or
p-OH).
This
work
represents
straightforward
method
to
synthesize
pyrrolo[1,2-a]indole
bearing
tetrasubstituted
carbon
stereocenter.
The
reaction
proceeds
smoothly
with
wide
array
substrate
tolerance
deliver
various
pyrrolo[1,2-a]indoles
in
up
93%
yield
98%
ee.
utility
this
is
highlighted
by
diverse
transformations
products
into
indole
derivatives.
Organic & Biomolecular Chemistry,
Год журнала:
2021,
Номер
19(35), С. 7544 - 7574
Опубликована: Янв. 1, 2021
This
review
focuses
on
recent
developments
in
the
synthesis
of
pyrrolo[1,2-
a
]indole
derivatives.
The
mechanism,
factors
affecting
yield
and
selectivity
product,
application
to
bioactive
molecules
are
explained.
