Advanced Materials,
Год журнала:
2021,
Номер
33(49)
Опубликована: Окт. 1, 2021
Bioprinting,
within
the
emerging
field
of
biofabrication,
aims
at
fabrication
functional
biomimetic
constructs.
Different
3D
bioprinting
techniques
have
been
adapted
to
bioprint
cell-laden
bioinks.
However,
single-material
oftentimes
fail
reproduce
complex
compositions
and
diversity
native
tissues.
Multi-material
as
an
approach
enables
heterogeneous
multi-cellular
constructs
that
replicate
their
host
microenvironments
better
than
approaches.
Here,
modalities
are
reviewed,
being
multi-material
is
discussed,
advantages
challenges,
encompassing
both
custom-designed
commercially
available
technologies
analyzed.
A
perspective
how
opens
up
new
opportunities
for
tissue
engineering,
model
therapeutics
development,
personalized
medicine
offered.
Green Chemistry,
Год журнала:
2021,
Номер
23(4), С. 1794 - 1804
Опубликована: Янв. 1, 2021
Thiyl
radical–polyphenol
Michael
addition
was
utilized
to
prepare
tannic
acid–thioctic
acid
(TATA)
hydrogel
under
mild
condition.
It
also
found
that
this
could
be
used
as
wound
adhesive
with
good
biocompatibility.
Abstract
Due
to
their
similarity
some
bio‐architectures,
for
example,
extracellular
matrix,
hydrogels
are
considered
as
bio‐inspired
networks
with
bio‐mimetic
and
bio‐functional
properties.
With
natural
cytocompatibility
biocompatibility,
nowadays
more
involved
in
various
bio‐applications
including
shape
morphing,
artificial
muscles,
soft
robotics,
regenerative
medicine,
so
on.
As
an
important
subclass,
stimuli‐responsive
have
been
attracting
interest
within
decades.
In
response
single
or
multi‐triggers
biological
microenvironment,
can
undergo
phase
transition,
stiffness
change,
biochemical
properties
activation,
which
make
them
intriguing
biomaterials
broad
applications
sensing,
drug
delivery,
tissue
engineering,
wound
healing.
This
review
presents
typical
synthetic
gelators
comprising
small
molecules
polymers
building
blocks
of
functional
architectures.
The
fabrication
strategies
varied
from
supramolecular
assembly
dynamic
covalent
binding
detailed.
Various
exogenous
endogenous,
physical
chemical,
stimuli
together
mechanism,
design
principle
demonstrated.
Through
recent
examples
different
perspectives,
such
bionic
devices,
dressing,
cargo
carrier,
the
benefits
opportunities
highlighted.
Finally,
current
challenges
future
prospects
view
translation
fundamental
researches
clinical
application
briefly
discussed.
Due
to
the
abuse
of
antibiotics
and
emergence
multidrug
resistant
microorganisms,
medical
devices,
related
biomaterials
are
at
high
risk
microbial
infection
during
use,
placing
a
heavy
burden
on
patients
healthcare
systems.
Metal-phenolic
networks
(MPNs),
an
emerging
organic-inorganic
hybrid
network
system
developed
gradually
in
recent
years,
have
exhibited
excellent
multifunctional
properties
such
as
anti-inflammatory,
antioxidant,
antibacterial
by
making
use
coordination
between
phenolic
ligands
metal
ions.
Further,
MPNs
received
widespread
attention
antimicrobial
infections
due
their
facile
synthesis
process,
biocompatibility,
brought
about
polyphenols
In
this
review,
different
categories
based
(nanoparticles,
coatings,
capsules,
hydrogels)
fabrication
strategies
summarized,
research
advances
applications
biomedical
fields
(e.g.,
skin
repair,
bone
regeneration,
etc.)
highlighted.
Journal of Advanced Research,
Год журнала:
2022,
Номер
44, С. 53 - 70
Опубликована: Апрель 16, 2022
With
rapid
development
in
agriculture
and
industry,
water
polluted
with
heavy
metallic
ions
has
come
to
be
a
serious
problem.
Adsorption-based
methods
are
simple,
efficient,
broadly
used
eliminate
metals.
Conventional
adsorption
materials
have
the
problems
of
secondary
environmental
contamination.
Hydrogels
considered
effective
adsorbents,
those
prepared
from
biopolymers
biocompatible,
biodegradable,
non-toxic,
safe
handle,
increasingly
adsorb
metal
ions.
The
natural
origin
easy
degradability
biopolymer
hydrogels
make
them
potential
for
remediation.
Its
absorption
capacity
enables
it
efficiently
various
pollutants
aqueous
environment,
its
internal
pore
channels
increase
specific
surface
area
adsorption,
which
can
provide
abundant
active
binding
sites
through
chemical
modification.
As
most
representative
hydrogels,
polysaccharide-based
diverse,
physically
chemically
stable,
undergo
complex
modifications
enhance
their
performance,
thus
exhibiting
superior
ability
remove
contaminants.
This
review
summarizes
preparation
followed
by
discussion
main
categories
applications
hydrogels.
Advanced Materials,
Год журнала:
2021,
Номер
33(49)
Опубликована: Окт. 1, 2021
Bioprinting,
within
the
emerging
field
of
biofabrication,
aims
at
fabrication
functional
biomimetic
constructs.
Different
3D
bioprinting
techniques
have
been
adapted
to
bioprint
cell-laden
bioinks.
However,
single-material
oftentimes
fail
reproduce
complex
compositions
and
diversity
native
tissues.
Multi-material
as
an
approach
enables
heterogeneous
multi-cellular
constructs
that
replicate
their
host
microenvironments
better
than
approaches.
Here,
modalities
are
reviewed,
being
multi-material
is
discussed,
advantages
challenges,
encompassing
both
custom-designed
commercially
available
technologies
analyzed.
A
perspective
how
opens
up
new
opportunities
for
tissue
engineering,
model
therapeutics
development,
personalized
medicine
offered.
