Stimuli-responsive polydopamine-based smart materials

Chemical Society Reviews, Год журнала: 2021, Номер 50(14), С. 8319 - 8343

Опубликована: Янв. 1, 2021

This review provides in-depth insight into the structural engineering of PDA-based materials to enhance their responsive feature and use them in construction stimuli-responsive smart materials.

Язык: Английский

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Metal Ion-Directed Functional Metal–Phenolic Materials

Chemical Reviews, Год журнала: 2022, Номер 122(13), С. 11432 - 11473

Опубликована: Май 10, 2022

Metal ions are ubiquitous in nature and play significant roles assembling functional materials fields spanning chemistry, biology, science. Metal-phenolic assembled from phenolic components the presence of metal through formation metal-organic complexes. Alkali, alkali-earth, transition, noble as well metalloids interacting with building blocks have been widely exploited to generate diverse hybrid materials. Despite extensive studies on synthesis metal-phenolic materials, a comprehensive summary how guide assembly compounds is lacking. A fundamental understanding engineering will facilitate specific properties. In this review, we focus diversity function material emerging applications. Specifically, discuss range underlying interactions, including (i) cation-π, (ii) coordination, (iii) redox, (iv) dynamic covalent highlight wide properties resulting these interactions. Applications (e.g., biological, catalytic, environmental) perspectives also highlighted.

Язык: Английский

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Tannic acid-based metal phenolic networks for bio-applications: a review

Journal of Materials Chemistry B, Год журнала: 2021, Номер 9(20), С. 4098 - 4110

Опубликована: Янв. 1, 2021

Strategic design for the fabrication of tannic acid-based metal phenolic networks. Various applications networks in biomedical fields.

Язык: Английский

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Mussel-inspired chemistry: A promising strategy for natural polysaccharides in biomedical applications

Progress in Polymer Science, Год журнала: 2021, Номер 123, С. 101472 - 101472

Опубликована: Окт. 18, 2021

Язык: Английский

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Amplification of Activated Near-Infrared Afterglow Luminescence by Introducing Twisted Molecular Geometry for Understanding Neutrophil-Involved Diseases

Journal of the American Chemical Society, Год журнала: 2022, Номер 144(8), С. 3429 - 3441

Опубликована: Янв. 20, 2022

Understanding the mechanism and progression of neutrophil-involved diseases (e.g., acute inflammation) is great importance. However, current available analytical methods neither achieve real-time monitoring nor provide dynamic information during pathological processes. Herein, a peroxynitrite (ONOO–) environmental pH dual-responsive afterglow luminescent nanoprobe designed synthesized. In presence ONOO– at physiological pH, nanoprobes show activated near-infrared luminescence, whose intensity lasting time can be highly enhanced by introducing aggregation-induced emission (AIE) effect with twisted molecular geometry into system. vivo studies using three diseased animal models demonstrate that sensitively reveal development process skin inflammation including infiltration first arrived neutrophils acidification initiating time, make fast accurate discrimination between allergy inflammation, rapidly screen antitumor drugs capable inducing immunogenic cell death. This work provides an alternative approach advanced probes permitting precise disease in real time.

Язык: Английский

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Versatile polyphenolic platforms in regulating cell biology

Chemical Society Reviews, Год журнала: 2022, Номер 51(10), С. 4175 - 4198

Опубликована: Янв. 1, 2022

Polyphenolic materials are a class of fascinating and versatile bioinspired for biointerfacial engineering. In particular, due to the presence active chemical groups, series unique physicochemical properties become accessible tunable as-prepared polyphenolic platforms, which could delicately regulate cell activities via cell-material contact-dependent interactions. More interestingly, polyphenols also affect behaviors contact-independent manner, arise their intrinsically functional characteristics (e.g., antioxidant photothermal behaviors). As such, comprehensive understanding on relationship between material desired biomedical applications, as well underlying mechanism at cellular molecular level would provide design principles accelerate lab-to-clinic translation platforms. this review, we firstly give brief overview hallmarks governed by surrounding cues, followed introduction engineering strategies. Subsequently, detailed discussion cell-polyphenols interfacial interaction was carefully provided. Lastly, applications were elaborated. We believe that review guidances rational multifunctional extend application window.

Язык: Английский

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Bioadhesive and conductive hydrogel-integrated brain-machine interfaces for conformal and immune-evasive contact with brain tissue

Matter, Год журнала: 2022, Номер 5(4), С. 1204 - 1223

Опубликована: Янв. 31, 2022

Язык: Английский

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Cellulose-Based Nanomaterials Advance Biomedicine: A Review

International Journal of Molecular Sciences, Год журнала: 2022, Номер 23(10), С. 5405 - 5405

Опубликована: Май 12, 2022

There are various biomaterials, but none fulfills all requirements. Cellulose biopolymers have advanced biomedicine to satisfy high market demand and circumvent many ecological concerns. This review aims present an overview of cellulose knowledge technical biomedical applications such as antibacterial agents, antifouling, wound healing, drug delivery, tissue engineering, bone regeneration. It includes extensive bibliography recent research findings from fundamental applied investigations. Cellulose-based materials tailorable obtain suitable chemical, mechanical, physical properties required for applications. The chemical structure allows modifications simple conjugation with several materials, including nanoparticles, without tedious efforts. They render the cheap, biocompatible, biodegradable, easy shape process.

Язык: Английский

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Nanostructured particles assembled from natural building blocks for advanced therapies

Chemical Society Reviews, Год журнала: 2022, Номер 51(11), С. 4287 - 4336

Опубликована: Янв. 1, 2022

Advanced treatments based on immune system manipulation, gene transcription and regulation, specific organ cell targeting, and/or photon energy conversion have emerged as promising therapeutic strategies against a range of challenging diseases. Naturally derived macromolecules (e.g., proteins, lipids, polysaccharides, polyphenols) increasingly found use fundamental building blocks for nanostructured particles their advantageous properties, including biocompatibility, biodegradability, inherent bioactivity, diverse chemical properties make them suitable advanced applications. This review provides timely comprehensive summary the broad natural in rapidly developing field therapeutics with insights to particles. We focus an up-to-date overview assembly using summarize key scientific preclinical milestones therapies, adoptive therapy, immunotherapy, active targeted drug delivery, photoacoustic therapy imaging, photothermal combinational therapy. A cross-comparison advantages disadvantages different are highlighted elucidate design principles such bio-derived nanoparticles toward improving performance adoption. Current challenges future research directions also discussed, which will accelerate our understanding designing, engineering, applying therapies.

Язык: Английский

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Reactive Oxygen Species‐Scavenging Nanosystems in the Treatment of Diabetic Wounds

Advanced Healthcare Materials, Год журнала: 2023, Номер 12(25)

Опубликована: Апрель 13, 2023

Diabetic wounds are characterized by drug-resistant bacterial infections, biofilm formation, impaired angiogenesis and perfusion, oxidative damage to the microenvironment. Given their complex nature, diabetic remain a major challenge in clinical practice. Reactive oxygen species (ROS), which have been shown trigger hyperinflammation excessive cellular apoptosis, play pivotal role pathogenesis of wounds. ROS-scavenging nanosystems recently emerged as smart multifunctional nanomedicines with broad synergistic applicability. The documented anti-inflammatory pro-angiogenic ability treatments predestines these promising options for treatment Yet, this context, therapeutic applicability efficacy be elucidated. Herein, ROS is deciphered, properties strengths capacity summarized. In addition, current challenges such potential future directions discussed through clinical-translational lens.

Язык: Английский

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