Organic Letters,
Год журнала:
2021,
Номер
23(16), С. 6461 - 6465
Опубликована: Авг. 4, 2021
A
novel
[2
+
1
3]
cyclization
reaction
for
the
synthesis
of
2-aryl-4-quinolinecarboxylates
from
aryl
methyl
ketones,
arylamines,
and
1,3-dicarbonyl
compounds
has
been
established.
This
metal-free
process
achieved
C–C
bond
cleavage
directly
as
a
single-carbon
synthon.
The
is
highly
efficient
good
substrate
compatibility
while
operating
under
mild
conditions.
method
practicability
successfully
realized
bioactive
molecules.
Green Chemistry,
Год журнала:
2021,
Номер
23(11), С. 3950 - 3954
Опубликована: Янв. 1, 2021
An
electrochemical
multicomponent
reaction
was
established
under
catalyst-,
chemical-oxidant-free
and
mild
conditions,
which
provides
an
eco-friendly
simple
protocol
for
constructing
4-selanylpyrazoles
from
easily
available
raw
materials
with
high
yields.
Organic Letters,
Год журнала:
2021,
Номер
23(11), С. 4363 - 4367
Опубликована: Май 20, 2021
The
synthesis
of
NH-free
pyrroles
via
Pd-catalyzed
annulation
enaminones
and
alkenes
is
reported.
With
the
catalysis
Pd(II),
activation
triple
C(sp2)-H
bonds,
including
one
internal
bond
in
enaminone,
has
been
activated
to
provide
various
pyrroles.
interesting
evolution
hydrogen
gas
from
reactions
observed
by
a
detector.
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(12), С. 2339 - 2358
Опубликована: Янв. 1, 2024
This
review
highlights
recent
advancements
in
the
synthesis
of
various
quinoline
derivatives
through
a
multi-component
approach
involving
different
types
catalysts
and
catalyst-free
reactions.
Organic Letters,
Год журнала:
2020,
Номер
23(1), С. 195 - 201
Опубликована: Дек. 23, 2020
Herein,
a
novel
method
for
the
gram-scale
synthesis
of
(E)-quinoxalinone
oximes
through
multicomponent
reaction
under
mild
conditions
is
described.
Such
transformation
was
performed
transition-metal-free
conditions,
affording
(E)-oximes
in
moderate-to-good
yield
recrystallization.
Our
methodology
demonstrates
successful
combination
Mannich-type
and
radical
coupling,
providing
green
practical
approach
potentially
bioactive
quinoxalinone-containing
molecules.
Green Chemistry,
Год журнала:
2021,
Номер
23(12), С. 4430 - 4434
Опубликована: Янв. 1, 2021
The
3-aminomethylated
imidazoheterocycles
were
efficiently
synthesized
in
one-step
via
a
four-component
reaction
of
equimolar
cheap
and
commercially
available
reactants
at
ambient
temperature
under
catalyst-,
oxidant-,
base-free
mild
conditions.
ACS Sustainable Chemistry & Engineering,
Год журнала:
2021,
Номер
9(40), С. 13663 - 13671
Опубликована: Сен. 29, 2021
Herein,
a
novel
and
green
multicomponent
transformation
for
the
α-bifunctionalization
of
methyl
ketones
enabled
by
heterogeneous
catalysis
solar
photocatalysis
has
been
described.
This
reaction
is
performed
in
water
under
an
air
atmosphere,
affording
corresponding
products
moderate-to-good
yield.
Our
shows
successful
combination
photocatalysis,
giving
sustainable
practical
alternative
modification
ketone
derivatives.
Organic Letters,
Год журнала:
2021,
Номер
23(21), С. 8527 - 8532
Опубликована: Окт. 20, 2021
Here
we
report
a
novel
Rh-catalyzed
C−H/C−H
alkenylation
of
N-arylmethanimines
with
vinylene
carbonate
acting
as
unit.
Forty
examples
C3,C4-nonsubstituted
quinolines
were
achieved
from
commercially
available
starting
materials.
This
identified
process
features
an
exceedingly
simple
system,
lower
loading
catalyst,
and
the
capacity
for
postfunctionalization
bioactive
molecules.
Green Chemistry Letters and Reviews,
Год журнала:
2022,
Номер
15(2), С. 337 - 372
Опубликована: Апрель 3, 2022
Quinolines
are
a
prominent
heterocyclic
motif
and
crucial
building
blocks
in
creating
physiologically
active
compounds.
Due
to
the
fast
development
of
novel
medicines
with
quinoline
nucleus,
numerous
research
papers
have
been
published
short
amount
time.
Therefore,
comprehend
present
state
nucleus
medicinal
chemistry
science,
it
is
necessary
combine
new
information
older
data.
So
far,
several
traditional
synthesis
techniques
reported
literature
synthesize
this
scaffold.
Pfitzinger,
Gould–Jacob,
Friedlander,
Skraup,
Doebner–von
Miller,
Conrad–Limpach
examples
old
synthetic
methods.
However,
they
need
expensive
demanding
conditions,
such
as
high
temperature,
use
non-biodegradable
chemical
compounds
degrade
ecosystem,
create
irritation
or
harm
pollutants,
represent
threat
environment.
processes
difficult
time-consuming
apparatus
set-up,
resulting
costs
pollutants.
As
result,
scientists
presently
developing
innovative
decrease
chemicals,
solvents,
catalysts,
which
detrimental
both
humans
we
attempted
shed
light
current
review
on
various
reactions
produce
quinolines
their
derivatives
using
green
