Advanced Materials,
Год журнала:
2023,
Номер
36(2)
Опубликована: Ноя. 14, 2023
Biomaterials
are
extensively
used
to
mimic
cell-matrix
interactions,
which
essential
for
cell
growth,
function,
and
differentiation.
This
is
particularly
relevant
when
developing
in
vitro
disease
models
of
organs
rich
extracellular
matrix,
like
the
liver.
Liver
involves
a
chronic
wound-healing
response
with
formation
scar
tissue
known
as
fibrosis.
At
early
stages,
liver
can
be
reverted,
but
progresses,
reversion
no
longer
possible,
there
cure.
Research
new
therapies
hampered
by
lack
adequate
that
replicate
mechanical
properties
biochemical
stimuli
present
fibrotic
Fibrosis
associated
changes
composition
matrix
directly
influence
behavior.
could
play
an
role
better
emulating
microenvironment.
In
this
paper,
recent
cutting-edge
biomaterials
creating
human
fibrosis
revised,
combination
cells,
bioprinting,
and/or
microfluidics.
These
technologies
have
been
instrumental
intricate
structure
unhealthy
promote
medium
perfusion
improves
growth
respectively.
A
comprehensive
analysis
impact
material
hints
cell-material
interactions
tridimensional
context
provided.
Marine Drugs,
Год журнала:
2024,
Номер
22(3), С. 134 - 134
Опубликована: Март 16, 2024
3D
bioprinting
is
a
disruptive,
computer-aided,
and
additive
manufacturing
technology
that
allows
the
obtention,
layer-by-layer,
of
complex
structures.
This
believed
to
offer
tremendous
opportunities
in
several
fields
including
biomedical,
pharmaceutical,
food
industries.
Several
processes
bio-ink
materials
have
emerged
recently.
However,
there
still
pressing
need
develop
low-cost
sustainable
with
superior
qualities
(excellent
mechanical,
viscoelastic
thermal
properties,
biocompatibility,
biodegradability).
Marine-derived
biomaterials,
polysaccharides
proteins,
represent
viable
renewable
source
for
formulations.
Therefore,
focus
this
review
centers
around
use
marine-derived
biomaterials
formulations
bio-ink.
It
starts
general
overview
followed
by
description
most
commonly
used
bioprinting,
special
attention
paid
chitosan,
glycosaminoglycans,
alginate,
carrageenan,
collagen,
gelatin.
The
challenges
facing
application
within
biomedical
pharmaceutical
along
future
directions
are
also
discussed.
Polymers,
Год журнала:
2022,
Номер
14(9), С. 1668 - 1668
Опубликована: Апрель 20, 2022
Organ-on-chips
(OOCs)
are
microfluidic
devices
used
for
creating
physiological
organ
biomimetic
systems.
OOC
technology
brings
numerous
advantages
in
the
current
landscape
of
preclinical
models,
capable
recapitulating
multicellular
assemblage,
tissue-tissue
interaction,
and
replicating
human
pathologies.
Moreover,
cancer
research,
OOCs
emulate
3D
hierarchical
complexity
vivo
tumors
mimic
tumor
microenvironment,
being
a
practical
cost-efficient
solution
tumor-growth
investigation
anticancer
drug
screening.
compact
easy-to-use
microphysiological
functional
units
that
recapitulate
native
function
mechanical
strain
cells
experience
bodies,
allowing
development
wide
range
applications
such
as
disease
modeling
or
even
diagnostic
devices.
In
this
context,
work
aims
to
review
scientific
literature
field
designed
urology
terms
fabrication
(principles
manufacture
materials
used),
kidney-on-chip
models
drug-toxicity
screening
kidney
modeling,
bladder-on-chip
urinary
tract
infections
bladder
prostate-on-chip
prostate
modeling.
Biomimetics,
Год журнала:
2023,
Номер
8(1), С. 55 - 55
Опубликована: Янв. 28, 2023
Biomaterial
research
has
led
to
revolutionary
healthcare
advances.
Natural
biological
macromolecules
can
impact
high-performance,
multipurpose
materials.
This
prompted
the
quest
for
affordable
solutions,
with
a
focus
on
renewable
biomaterials
wide
variety
of
applications
and
ecologically
friendly
techniques.
Imitating
their
chemical
compositions
hierarchical
structures,
bioinspired
based
materials
have
elevated
rapidly
over
past
few
decades.
Bio-inspired
strategies
entail
extracting
fundamental
components
reassembling
them
into
programmable
biomaterials.
method
may
improve
its
processability
modifiability,
allowing
it
meet
application
criteria.
Silk
is
desirable
biosourced
raw
material
due
high
mechanical
properties,
flexibility,
bioactive
component
sequestration,
controlled
biodegradability,
remarkable
biocompatibility,
inexpensiveness.
regulates
temporo-spatial,
biochemical
biophysical
reactions.
Extracellular
factors
regulate
cellular
destiny
dynamically.
review
examines
structural
functional
properties
silk
scaffolds.
We
explored
types,
composition,
architecture,
topography,
3D
geometry
unlock
body’s
innate
regenerative
potential,
keeping
in
mind
novel
film,
fiber,
other
potential
forms,
coupled
facile
changes,
ability
match
requirements
specific
tissues.
Materials & Design,
Год журнала:
2023,
Номер
229, С. 111885 - 111885
Опубликована: Март 31, 2023
Vascularization
plays
a
crucial
role
in
transporting
and
exchanging
nutrients
oxygen
between
implanted
grafts
with
the
host
tissue.
In
biofabrication
of
grafts,
remodeling
vascular
networks
can
accelerate
vascularized
tissue
repair
regeneration.
Given
heterogeneity
tissues,
traditional
scaffold
manufacturing
techniques
cannot
effectively
achieve
various
scales
vitro
vivo
biomimetic.
recent
years,
3D
bioprinting
technologies
have
been
widely
used
fabricating
for
regeneration
due
to
their
shape
customizability,
simple
procedure,
reproducibility,
precise
multi-dimensional
control.
With
rapid
development
technologies,
bioprinting-based
strategies
gradually
applied
construction
tissues.
Based
on
this
background,
our
study
aimed
review
advances,
challenges,
future
perspectives
based
The
techniques,
bioinks,
seed
cells,
growth
factors
were
also
enrolled
review.
addition,
history,
vessel
formation
mechanism,
histology
discussed.
Advanced Materials,
Год журнала:
2023,
Номер
36(2)
Опубликована: Ноя. 14, 2023
Biomaterials
are
extensively
used
to
mimic
cell-matrix
interactions,
which
essential
for
cell
growth,
function,
and
differentiation.
This
is
particularly
relevant
when
developing
in
vitro
disease
models
of
organs
rich
extracellular
matrix,
like
the
liver.
Liver
involves
a
chronic
wound-healing
response
with
formation
scar
tissue
known
as
fibrosis.
At
early
stages,
liver
can
be
reverted,
but
progresses,
reversion
no
longer
possible,
there
cure.
Research
new
therapies
hampered
by
lack
adequate
that
replicate
mechanical
properties
biochemical
stimuli
present
fibrotic
Fibrosis
associated
changes
composition
matrix
directly
influence
behavior.
could
play
an
role
better
emulating
microenvironment.
In
this
paper,
recent
cutting-edge
biomaterials
creating
human
fibrosis
revised,
combination
cells,
bioprinting,
and/or
microfluidics.
These
technologies
have
been
instrumental
intricate
structure
unhealthy
promote
medium
perfusion
improves
growth
respectively.
A
comprehensive
analysis
impact
material
hints
cell-material
interactions
tridimensional
context
provided.
