Nickel‐Catalyzed Reductive Coupling of Carboxylic Acids with Disulfides to Access Thioesters

Advanced Synthesis & Catalysis, Год журнала: 2023, Номер 365(23), С. 4233 - 4240

Опубликована: Окт. 27, 2023

Abstract A nickel‐catalyzed reductive cross coupling reaction of carboxylic acids with disulfides is described. The readily available and inexpensive acid activated in situ by the formation a mixed anhydride. transformation occurs at room temperature wide functional group tolerance to efficiently generate structurally diverse thioesters. Moreover, tolerated broad substrate scope, including sterically hindered disulfides. Ultimately, this powerful method could be applied late‐stage functionalization for construction thioesters, affording convenient practical tactic construct carbon‐sulfur bonds.

Язык: Английский

---

Construction of alkynyl and acyl disulfides directly through thiol-modification withN-alkynylthio phthalimides under acid catalysis

Organic Chemistry Frontiers, Год журнала: 2023, Номер 10(8), С. 2070 - 2074

Опубликована: Янв. 1, 2023

Acid-catalyzed disulfuration and rearrangement have been disclosed for the construction of alkynyl or acyl disulfides from thiols N -alkynylthio phthalimides, enabling access to disulfide-modified thiodrugs, thiopeptides thioglycosides.

Язык: Английский

---

The radical chemistry of N-sulfenyl phthalimides/succinimides for C S bonds formation

Tetrahedron Letters, Год журнала: 2024, Номер 144, С. 155153 - 155153

Опубликована: Июнь 17, 2024

Язык: Английский

---

Transition metal-free synthesis of polyfluoroaryl sulfides via S-transfer reaction

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(19), С. 5558 - 5563

Опубликована: Янв. 1, 2024

A simple, general, thiol- and metal-free method for the synthesis of symmetrical unsymmetrical polyfluorodiaryl sulfides polyfluoroaryl-alkyl sulfides.

Язык: Английский

---

Synthesis of Unsymmetrical Disulfides via Photocatalytic Hydrodisulfuration

ACS Catalysis, Год журнала: 2024, Номер unknown, С. 18237 - 18246

Опубликована: Ноя. 26, 2024

Язык: Английский

---