Photocatalyzed Minisci-type reactions for late-stage functionalization of pharmaceutically relevant compounds
Green Chemistry,
Год журнала:
2024,
Номер
26(7), С. 3595 - 3626
Опубликована: Янв. 1, 2024
The
application
of
photocatalyzed
Minisci-type
reactions
in
LSF
accelerates
the
discovery
drug
candidates
a
green
way.
Язык: Английский
Metal- and photosensitizer-free cross-dehydrogenative coupling through photoinduced energy transfer
Green Chemistry,
Год журнала:
2024,
Номер
26(8), С. 4742 - 4748
Опубликована: Янв. 1, 2024
This
study
introduces
a
novel,
eco-friendly
method
for
Minisci
alkylation
without
harmful
catalysts,
advancing
sustainable
pharmaceutical
synthesis
through
energy
transfer
from
heteroarenes
to
peroxide,
offering
significant
environmental
benefits.
Язык: Английский
Regioselective Homolytic C2–H Borylation of Unprotected Adenosine and Adenine Derivatives via Minisci Reaction
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(31), С. 21428 - 21441
Опубликована: Июль 25, 2024
A
Minisci-type
borylation
of
unprotected
adenosine,
adenine
nucleotide,
and
adenosine
analogues
was
successfully
achieved
through
photocatalysis
or
thermal
activation.
Despite
the
challenges
posed
by
presence
two
potential
reactive
sites
(C
Язык: Английский
Iridium(iii)-catalyzed photoredox cross-coupling of alkyl bromides with trialkyl amines: access to α-alkylated aldehydes
Chemical Communications,
Год журнала:
2024,
Номер
60(41), С. 5435 - 5438
Опубликована: Янв. 1, 2024
A
C(sp
3
)–C(sp
)
cross
coupling
approach
based
on
an
iridium-photocatalytic
radical
process
has
been
developed
for
the
synthesis
of
α-alkylated
aldehydes
from
alkyl
bromides
and
trialkyl
amines.
Язык: Английский
Metal-free, direct acylation of purines to access C6-acylated purine derivatives induced by TBHP via Minisci-type reaction
New Journal of Chemistry,
Год журнала:
2024,
Номер
48(12), С. 5167 - 5172
Опубликована: Янв. 1, 2024
The
highly
C
6
-regioselective
acylation
of
purines
with
aldehydes
was
developed
to
access
-acylated
via
green
radical
reactions
without
metal
catalysts
or
light.
Язык: Английский
Photoinduced HCl-Mediated Cross-Dehydrogenative Coupling of Quinolines with Alcohols and Ethers
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 12, 2024
Via
light
irradiation,
cross-dehydrogenative
coupling
of
quinolines
with
alcohols
and
ethers
was
achieved
under
mild
conditions.
A
stoichiometric
amount
HCl
room
temperature
were
necessary
to
promote
the
reaction.
green
Minisci-type
reaction
performed
without
an
oxidant
or
a
transition-metal
catalyst.
Язык: Английский