Photoinduced HCl-Mediated Cross-Dehydrogenative Coupling of Quinolines with Alcohols and Ethers DOI
Feixiang Guo,

Yingchang Guo,

Qianqian Sun

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 12, 2024

Via light irradiation, cross-dehydrogenative coupling of quinolines with alcohols and ethers was achieved under mild conditions. A stoichiometric amount HCl room temperature were necessary to promote the reaction. green Minisci-type reaction performed without an oxidant or a transition-metal catalyst.

Language: Английский

Photocatalyzed Minisci-type reactions for late-stage functionalization of pharmaceutically relevant compounds DOI
Xiaotong Zhang, Shuqi Li, Feng Qiu

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 26(7), P. 3595 - 3626

Published: Jan. 1, 2024

The application of photocatalyzed Minisci-type reactions in LSF accelerates the discovery drug candidates a green way.

Language: Английский

Citations

16
Metal- and photosensitizer-free cross-dehydrogenative coupling through photoinduced energy transfer DOI
Bo Liu, Qiong Wang, Bin Cheng

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 26(8), P. 4742 - 4748

Published: Jan. 1, 2024

This study introduces a novel, eco-friendly method for Minisci alkylation without harmful catalysts, advancing sustainable pharmaceutical synthesis through energy transfer from heteroarenes to peroxide, offering significant environmental benefits.

Language: Английский

Citations

5
Regioselective Homolytic C2–H Borylation of Unprotected Adenosine and Adenine Derivatives via Minisci Reaction DOI

Yangyan Li,

Yutong Zhou,

Dazhi Zhou

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: 146(31), P. 21428 - 21441

Published: July 25, 2024

A Minisci-type borylation of unprotected adenosine, adenine nucleotide, and adenosine analogues was successfully achieved through photocatalysis or thermal activation. Despite the challenges posed by presence two potential reactive sites (C

Language: Английский

Citations

3
Iridium(iii)-catalyzed photoredox cross-coupling of alkyl bromides with trialkyl amines: access to α-alkylated aldehydes DOI
Gaurav Shukla, Malkeet Singh,

Saurabh Singh

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(41), P. 5435 - 5438

Published: Jan. 1, 2024

A C(sp 3 )–C(sp ) cross coupling approach based on an iridium-photocatalytic radical process has been developed for the synthesis of α-alkylated aldehydes from alkyl bromides and trialkyl amines.

Language: Английский

Citations

1
Metal-free, direct acylation of purines to access C6-acylated purine derivatives induced by TBHP via Minisci-type reaction DOI

Chunhui Zou,

Mingwu Yu,

Zhongkai Jiang

et al.

New Journal of Chemistry, Journal Year: 2024, Volume and Issue: 48(12), P. 5167 - 5172

Published: Jan. 1, 2024

The highly C 6 -regioselective acylation of purines with aldehydes was developed to access -acylated via green radical reactions without metal catalysts or light.

Language: Английский

Citations

0
Photoinduced HCl-Mediated Cross-Dehydrogenative Coupling of Quinolines with Alcohols and Ethers DOI
Feixiang Guo,

Yingchang Guo,

Qianqian Sun

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 12, 2024

Via light irradiation, cross-dehydrogenative coupling of quinolines with alcohols and ethers was achieved under mild conditions. A stoichiometric amount HCl room temperature were necessary to promote the reaction. green Minisci-type reaction performed without an oxidant or a transition-metal catalyst.

Language: Английский

Citations

0