Journal of Materials Chemistry B,
Год журнала:
2024,
Номер
12(22), С. 5418 - 5430
Опубликована: Янв. 1, 2024
The
novel
material
Co@Fe
MOG
was
designed
to
treat
infected
wounds
in
wound
healing.
ROS
induced
by
electron
transfer
between
Fe
3+
/Fe
2+
and
Co
/Co
the
basis
for
colorimetric
sensing
non-antibiotic
antibacterial
activity.
Abstract
Cascade
reactions
are
described
as
efficient
and
versatile
tools,
organized
catalytic
cascades
can
significantly
improve
the
efficiency
of
chemical
interworking
between
nanozymes.
They
have
attracted
great
interest
in
many
fields
such
chromogenic
detection,
biosensing,
tumor
diagnosis,
therapy.
However,
how
to
selectively
kill
cells
by
enzymatic
without
harming
normal
cells,
well
exploring
two
or
more
enzyme‐engineered
nanoreactors
for
cascading
reactions,
remain
challenges
field
targeted
specific
cancer
diagnostics
The
latest
research
advances
nanozyme‐catalyzed
cascade
processes
diagnosis
therapy
this
article.
Here,
various
sensing
strategies
summarized,
tumor‐specific
diagnostics.
Targeting
mechanisms
treatment
using
nanozymes
classified
analyzed,
“elements”
“dimensions”
nanozymes,
types,
designs
structure,
assembly
modes
highly
active
a
variety
new
targeting
based
on
reaction
Finally,
integrated
application
systems
tumor‐targeted
diagnostic
is
which
will
lay
foundation
design
rational,
efficient,
therapeutic
modalities
future.
Asian Journal of Pharmaceutical Sciences,
Год журнала:
2025,
Номер
20(1), С. 101017 - 101017
Опубликована: Янв. 10, 2025
Biological
nanotechnologies
based
on
functional
nanoplatforms
have
synergistically
catalyzed
the
emergence
of
cancer
therapies.
As
a
subtype
metal-organic
frameworks
(MOFs),
zeolitic
imidazolate
(ZIFs)
exploded
in
popularity
field
biomaterials
as
excellent
protective
materials
with
advantages
conformational
flexibility,
thermal
and
chemical
stability,
controllability.
With
these
superior
properties,
applications
ZIF-based
combination
various
therapies
for
treatment
grown
rapidly
recent
years,
showing
remarkable
achievements
great
potential.
This
review
elucidates
advancements
use
ZIFs
drug
delivery
agents
therapy.
The
structures,
synthesis
methods,
modifiers
used
oncotherapy
are
presented.
Recent
advances
application
nanoparticles
single
or
tumor
treatments
reviewed.
Furthermore,
future
prospects,
potential
limitations,
challenges
nanomaterials
discussed.
We
except
to
fully
explore
present
clear
outline
their
an
effective
help
them
achieve
early
clinical
application.
Pharmaceutics,
Год журнала:
2024,
Номер
16(5), С. 603 - 603
Опубликована: Апрель 29, 2024
Sonodynamic
therapy
(SDT)
has
attracted
significant
attention
in
recent
years
as
it
is
an
innovative
approach
to
tumor
treatment.
It
involves
the
utilization
of
sound
waves
or
ultrasound
(US)
activate
acoustic
sensitizers,
enabling
targeted
drug
release
for
precise
This
review
aims
provide
a
comprehensive
overview
SDT,
encompassing
its
underlying
principles
and
therapeutic
mechanisms,
applications
nanomaterials,
potential
synergies
with
combination
therapies.
The
begins
by
introducing
fundamental
principle
SDT
delving
into
intricate
mechanisms
through
which
facilitates
A
detailed
analysis
presented,
outlining
how
effectively
destroys
cells
modulating
mechanisms.
Subsequently,
this
explores
diverse
range
nanomaterials
utilized
highlights
their
specific
contributions
enhancing
treatment
outcomes.
Furthermore,
combine
other
modalities
such
photothermal
(PTT)
chemotherapy
discussed.
These
combined
approaches
aim
synergistically
improve
efficacy
while
mitigating
side
effects.
In
conclusion,
emerges
promising
frontier
that
offers
personalized
effective
options
revolutionize
patient
care.
As
research
progresses,
poised
play
pivotal
role
shaping
future
landscape
oncology
providing
patients
broader
spectrum
efficacious
tailored
options.