Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings

Gels, Год журнала: 2025, Номер 11(2), С. 123 - 123

Опубликована: Фев. 7, 2025

Recent advancements in wound dressing materials have significantly improved acute and chronic management by addressing challenges such as infection control, moisture balance, enhanced healing. Important progress has been made, especially with hydrogels, foams, antimicrobial for creating optimized dressings. Hydrogels are known maintaining optimal levels, while foam dressings excellent exudate absorbents. Meanwhile, incorporates various agents to reduce risks. These options healing time focusing on customized patient needs. Therefore, this review highlights the newest research prototypes applications, emphasizing their particular benefits clinical importance. Innovations stimuli-responsive hydrogels hybrid bioengineered composites discussed relation properties, including responsiveness pH, temperature, glucose, or enzymes drug delivery precision. Moreover, ongoing trials included, demonstrating potential of emerging solutions be soon translated from laboratory settings. By discussing interdisciplinary approaches that integrate advanced materials, nanotechnology, biological insights, work provides a contemporary framework patient-centric, efficient care strategies.

Язык: Английский

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Improved wound care via novel dextran and boric acid loaded wound healing gel in excision mice wound model

Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер unknown, С. 106586 - 106586

Опубликована: Янв. 1, 2025

Язык: Английский

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Platelet extracellular vesicles-loaded hydrogel bandages for personalized wound care

Trends in biotechnology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Hydrogels for Wound Dressings: Applications in Burn Treatment and Chronic Wound Care

Journal of Composites Science, Год журнала: 2025, Номер 9(3), С. 133 - 133

Опубликована: Март 13, 2025

Severe skin injuries such as burns and chronic wounds are a subject of interest in the medical field, they require much attention. These types susceptible to serious complications, which can worsen health patients reduce their quality life. Hydrogels have emerged innovative wound dressings for treating acute wounds, including burns, diabetic foot ulcers, venous leg pressure ulcers. polymeric networks provide moist environment, promote cellular migration, offer antimicrobial properties, being recognized superior conventional dressings. This review aims explore recent advancements hydrogel-based dressings, emphasizing state-of-the-art technologies used this purpose trend achieving personalized therapeutic approaches. Despite promising vitro vivo findings described review, further clinical validation large-scale manufacturing optimizations required widespread adoption.

Язык: Английский

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Skin-inspired elastomer-hydrogel Janus fibrous membrane creates a superior pro-regenerative microenvironment toward complete skin regeneration

Biomaterials Advances, Год журнала: 2025, Номер 170, С. 214227 - 214227

Опубликована: Фев. 8, 2025

Язык: Английский

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A dual-action strategy: Wound microenvironment responsive hydrogel and exosome-mediated glucose regulation enhance inside-out diabetic wound repair

Journal of Controlled Release, Год журнала: 2025, Номер unknown, С. 113716 - 113716

Опубликована: Апрель 1, 2025

Язык: Английский

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Mechanically robust, mouldable, dynamically crosslinked hydrogel flap with multiple functionalities for accelerated deep skin wound healing

Biomaterials Advances, Год журнала: 2025, Номер 169, С. 214195 - 214195

Опубликована: Янв. 20, 2025

Язык: Английский

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Evaluating the Wound Healing Potential of Characterized Bergenia ciliata–Loaded Salvia hispanica Hydrogel in Diabetic Mice

Microscopy Research and Technique, Год журнала: 2025, Номер unknown

Опубликована: Фев. 27, 2025

ABSTRACT The current study assessed the wound healing potential of Bergenia ciliata (BC) extract, BC‐loaded Salvia hispanica hydrogel (CH‐BC) and nanoparticles (NPs)–loaded (CH‐BC AgNPs/NPs‐loaded hydrogel) using in vitro vivo studies. prepared its components were analyzed UV–visible spectrophotometry (UV–vis), scanning electron microscopy (SEM), dynamic light scattering (DLS) analysis/particle size analyzer (PSA), zeta potential, fourier transform infrared spectrometry (FT‐IR), x‐ray diffraction (XRD). Peaks peak shifts at 450–460, 250–260, 270–280 nm UV–vis FT‐IR (500–4000 cm −1 ) confirmed extract loading various functional group presence. DLS nanometric BC AgNP while indicated slightly negative charge hydrogel. SEM average topography –mediated (BC AgNPs) AgNPs loaded AgNPs), XRD peaks 2ϴ (10–70) topographical crystalline porous nature materials. showed higher radical scavenging (74.19% ± 1.84%) iron chelation activity (93.70 2.20) 50 25 μL/mL, respectively, CH‐BC produced lowest (48.97% 3.0%) 75 μL/mL (54.35 3.24). Moreover, Chia (CH) synergistically enhanced (1.30%) DPPH scavenging. contraction percentage augmented as potent candidate for (14th day). These findings further supported by a significant ( p < 0.001) restoration MMP2 (184.6 11.7 pg/mL), TIMPs (184.8 15.7 GPx (153.4 11.5 IL‐6 (10 1 pg/mL) levels compared to those diabetic control. normal reepithelization, angiogenesis, maturation wounds treatment groups after histological analysis strengthened supposed rationale that CH, along with AgNPs, can act improve therapeutic results. Hence, appeared sustainable, biocompatible, nontoxic agent paved way futuristic biomedical investigations.

Язык: Английский

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State-of-the-art in natural hydrogel-based wound dressings: Design, functionalization, and fabrication approaches

Advances in Colloid and Interface Science, Год журнала: 2025, Номер 342, С. 103527 - 103527

Опубликована: Апрель 25, 2025

Язык: Английский

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The Printed Path to Healing: Advancing Wound Dressings through Additive Manufacturing

Advanced Healthcare Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 5, 2025

Abstract Wound care challenges healthcare systems worldwide as traditional dressings often fall short in addressing the diverse and complex nature of wound healing. Given conventional treatments limitations, innovative alternatives are urgent. Additive manufacturing (AM) has emerged a distinct transformative approach for developing advanced dressings, offering unprecedented functionality customization. Besides exploring AM processes state‐of‐the‐art, this review comprehensively examines application to produce cellular‐compatible bioactive, therapeutic agent delivery, patient‐centric, responsive dressings. This distinguishes itself from published literature by covering variety types summarizing important data, including used materials, process/technology, printing parameters, findings vitro, ex vivo, vivo studies. The prospects enhancing healing outcomes also analyzed translational cost‐effective manner.

Язык: Английский

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