Chemistry - A European Journal,
Год журнала:
2024,
Номер
30(40)
Опубликована: Май 13, 2024
The
effective
transition
metal-free
photoredox/bismuth
dual
catalytic
reductive
dialkylation
of
nitroarenes
with
benzaldehydes
has
been
reported.
nitroarene
reduction
through
visible
light-driven
photoredox
catalysis
was
integrated
subsequent
anilines
under
bismuth
to
enable
the
cascade
alkylation
carbonyls.
Salient
features
this
relay
system
include
mild
reaction
conditions,
no
requirement
for
metal
catalysts,
easy
handling,
step-economy,
and
high
selectivity.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(5), С. 3419 - 3429
Опубликована: Фев. 16, 2024
Herein,
we
describe
a
dual
photocatalytic
system
to
synthesize
phenol–pyridinium
salts
using
visible
light.
Utilizing
both
electron
donor–acceptor
(EDA)
complex
and
iridium(III)
cycles,
the
C–N
cross-coupling
of
unprotected
phenols
pyridines
proceeds
in
presence
oxygen
furnish
pyridinium
salts.
Photocatalytic
generation
phenoxyl
radical
cations
also
enabled
nucleophilic
aromatic
substitution
(SNAr)
fluorophenol
with
an
electron-poor
pyridine.
Spectroscopic
experiments
were
conducted
probe
mechanism
reaction
selectivity.
The
unique
reactivity
these
displayed
several
derivatization
reactions,
providing
rapid
access
diverse
chemical
space.
Organic & Biomolecular Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
We
have
developed
an
efficient
solvent-free
protocol
for
amide
bond
formation
using
Boc
2
O/DMAP,
involving
the
in
situ
generation
of
a
mixed
anhydride
and
proceeding
via
sequential
mechanism.
Green Chemistry,
Год журнала:
2023,
Номер
25(23), С. 9672 - 9679
Опубликована: Янв. 1, 2023
A
H
2
O-promoted
and
(NH
4
)
CO
3
-enabled
defluoroiminization
reaction
of
fluoroalkyl
alkenes
for
the
synthesis
fluoroalkylated
1,5-diazapentadienes
has
been
developed.
Chemical Communications,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
An
organocatalytic
approach
using
stable,
cost-effective
ammonium
salts
for
asymmetric
sulfinylation,
achieving
a
broad
range
of
enantioenriched
sulfinamides
was
disclosed.
Journal of the American Chemical Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 27, 2025
Ammonia
stands
out
as
the
most
available,
cost-effective,
and
atom-economical
source
of
nitrogen
for
organic
synthesis.
In
laboratory,
it
is
safely
conveniently
handled
in
aqueous
solution.
Despite
advantages,
direct
application
ammonia
field
transition-metal
catalysis
remains
a
significant
challenge.
this
study,
we
report
first
ruthenium-catalyzed
allylic
substitution
using
ammonia.
The
catalytic
system,
consisting
[Cp*Ru(MeCN)3]PF6
phenoxythiazoline
ligand,
enables
enantiospecific
amination
tertiary
carbonates
media
affords
enantioenriched
primary
amines
single
regioisomers
high
yields.
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 8, 2025
We
herein
report
a
one-pot,
three-component
coupling
of
arylhydrazine
HCl
salts
with
aryl
aldehydes
to
synthesize
triarylmethane
scaffold.
This
reaction
proceeds
under
simple,
mild,
and
practical
conditions
without
the
need
for
an
additional
Bro̷nsted
or
Lewis
acid
additive,
accommodating
broad
substrate
scope
good
excellent
yields.
Furthermore,
this
methodology
can
be
scaled
up
allows
access
diverse
range
derivatives.
Mechanistic
studies
suggest
that
in
situ
formed
hydrazone
intermediate
is
essential
high
efficiency
selectivity
transformation.
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(23), С. 4641 - 4646
Опубликована: Янв. 1, 2024
A
novel
two-step
synthesis
of
β-trifluoromethyl
primary
amines
from
readily
available
α-(trifluoromethyl)styrenes
and
phthalimide
is
developed.
The
first
step
involves
a
hydroamination
between
(PhthNH)
with
the
assistance
base.
Next,
hydrazinolysis
resulting
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(15), С. 10693 - 10697
Опубликована: Июль 15, 2024
Pd/DPEphos-catalyzed
direct
amination
of
allylic
alcohols
with
readily
available
ammonium
acetate
as
a
nitrogen
source
provides
access
to
convenient
and
scalable
syntheses
primary
amines
high
monoallylation
selectivity.
Mechanistic
studies
revealed
that
functions
Brønsted
acid
activate
the
hydroxyl
groups
inhibit
overreaction.
