Electrooxidative Ni‐catalyzed Decarboxylation of Arylacetic Acids towards the Synthesis of carbonyls under Air Conditions DOI
Zhengjiang Fu, Junhua Zeng,

Cheng Xiong

et al.

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 16, 2024

Abstract After systematic realization of decarboxylative functionalization carboxylic acids under heating conditions in our group, we herein reported an electrochemical method for Ni‐catalyzed oxygenation arylacetic open air conditions. The protocol provided corresponding carbonyls including aldehydes and ketones moderate to satisfactory yields with good functional group tolerance, furthermore, the practicability advantage was highlighted through oxidative decarboxylation acid‐containing drugs preformation scalable transformation. Mechanistic studies demonstrated that possible involvement free radical intermediate conversion.

Language: Английский

Electrochemical Difunctionalization of Alkenes DOI Open Access

Yin Zhang,

Zilong Zhou,

Jin‐Heng Li

et al.

The Chemical Record, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 3, 2025

Abstract Owing to their wide utilizations in synthesis and products prevalence numerous natural products, pharmaceuticals functional materials, the alkene difunctionalization methods for selective transformations of olefins are important have attracted much attention form synthetic chemists. Among them, electrochemical reaction is particularly promising has becoming a potent sustainable tool alkenes into vicinal difunctionalized structures organic through simultaneous incorporation two groups. Herein, we summarize recent progress reactions according types as well category radicals over past five years. By selecting remarkable examples, elaborately discussed substrate scope mechanisms olefin reaction.

Language: Английский

Citations

0
Mn-Catalyzed Electrooxidative Radical Cascade Cyclization for the Synthesis of 6-Phosphorylated Quinoxalino[2,1-b]quinazolin-12-ones DOI
Huanping Xie,

Jiongjiong Duan,

Yi Cao

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 12, 2024

Due to their important potential medicinal value, chemists are pursuing mild and efficient methods synthesize structurally diverse quinazolinone derivatives. In this paper, a series of isocyano-tethered

Language: Английский

Citations

0
Electrooxidative Ni‐catalyzed Decarboxylation of Arylacetic Acids towards the Synthesis of carbonyls under Air Conditions DOI
Zhengjiang Fu, Junhua Zeng,

Cheng Xiong

et al.

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 16, 2024

Abstract After systematic realization of decarboxylative functionalization carboxylic acids under heating conditions in our group, we herein reported an electrochemical method for Ni‐catalyzed oxygenation arylacetic open air conditions. The protocol provided corresponding carbonyls including aldehydes and ketones moderate to satisfactory yields with good functional group tolerance, furthermore, the practicability advantage was highlighted through oxidative decarboxylation acid‐containing drugs preformation scalable transformation. Mechanistic studies demonstrated that possible involvement free radical intermediate conversion.

Language: Английский

Citations

0