JMIR mhealth and uhealth,
Год журнала:
2023,
Номер
unknown
Опубликована: Июль 26, 2023
Despite
widespread
awareness
of
healthy
eating
principles,
many
individuals
struggle
to
translate
this
knowledge
into
consistent,
sustainable
dietary
change.
Food
recommender
systems,
increasingly
used
in
various
settings,
offer
the
potential
for
personalized
guidance
and
behavior
change
support.
However,
traditional
approaches
may
prioritize
user
preferences
or
popularity
metrics
without
sufficiently
considering
long-term
nutritional
goals.
This
can
inadvertently
reinforce
unhealthy
patterns.
Emerging
research
suggests
that
incorporating
explanations
systems
increase
transparency,
promote
informed
decision-making,
potentially
influence
food
choices.
Yet,
effectiveness
promoting
choices
within
complex,
real-world
environments
remain
largely
unexplored.
study
aims
investigate
design,
implementation,
preliminary
evaluation
a
system
integrates
catering
application.
We
seek
understand
how
such
while
addressing
inherent
tensions
between
control,
meal
variety,
need
nutritionally
sound
recommendations.
Specifically,
our
objectives
are
(1)
identify
key
design
considerations
recommenders
balance
personalization,
guidance,
experience;
(2)
conduct
proof-of-principle
real-life
setting
assess
system's
effect
on
understanding,
trust,
An
iterative,
user-centered
process
guided
development
refinement
across
4
phases:
(Phase
0)
an
exploratory
qualitative
(N=26)
stakeholder
needs
initial
impressions,
(Phases
1
2)
rapid
prototyping
deployments
(N=45
N=16,
respectively)
iteratively
improve
usability
features,
3)
with
employees
(N=136)
evaluate
set
collected
mix
data,
including
usage
logs,
pre-
post-study
questionnaires,
in-app
feedback,
post-Food
Frequency
Questionnaire
establish
profiles.
Although
we
experienced
high
drop-out
(77%
after
7
weeks),
motivated
remaining
participants
valued
personalization
particularly
ability
configure
allergies
lifestyle
preferences.
Explanations
increased
understanding
recommendations
created
sense
even
when
options
did
not
fully
align.
mismatch
persisted
individual
optimal
highlights
challenge
balancing
promotion
eating.
Integrating
might
be
promising
supporting
healthier
creating
more
Our
findings
could
highlight
importance
control
both
practical
limitations
service
settings
While
resolving
tension
immediate
health
goals
is
ongoing
challenge,
play
crucial
role
conscious
decision-making.
Diet
constitutes
a
major
source
of
nutrient
flow
to
the
gut
microbes.
As
such,
it
can
be
used
help
shape
microbiome.
Fecal
microbiota
transplantation
(FMT)
is
an
increasingly
promising
therapy
in
disease
states
beyond
recurrent
Clostridioides
difficile
infection,
but
diet
largely
overlooked
for
its
potential
optimize
this
therapy.
Therefore,
aim
scoping
review
present
literature
landscape
that
captures
pre-
and
post-FMT
dietary
intake
humans,
identify
research
gaps,
provide
recommendations
future
research.
A
comprehensive
search
strategy
was
developed
searches
were
run
five
databases.
Studies
included
if
they
discussed
adults
who
underwent
FMT
any
recognized
treatment
indication
had
as
study
objective,
encompassed
studies
with
interventions
foods
supplements.
The
initial
screening
identified
total
7721
articles,
which
18
met
inclusion
criteria
review.
heterogeneous,
taken
together,
introduce
framework
defines
important
nutritional
considerations
both
donors
recipients
period
around
dosing.
This
summarized
highlights
opportunities
available
develop
FMT-based
precision
nutrition
strategies
clinical
efficacy.
Proceedings of the National Academy of Sciences,
Год журнала:
2023,
Номер
120(27)
Опубликована: Июнь 27, 2023
Eating
a
varied
diet
is
central
tenet
of
good
nutrition.
Here,
we
develop
molecular
tool
to
quantify
human
dietary
plant
diversity
by
applying
DNA
metabarcoding
with
the
chloroplast
trnL-P6
marker
1,029
fecal
samples
from
324
participants
across
two
interventional
feeding
studies
and
three
observational
cohorts.
The
number
taxa
per
sample
(plant
richness
or
pMR)
correlated
recorded
intakes
in
diets
indices
calculated
food
frequency
questionnaire
typical
(ρ
=
0.40
0.63).
In
adolescents
unable
collect
validated
survey
data,
trnL
detected
111
taxa,
86
consumed
more
than
one
individual
four
(wheat,
chocolate,
corn,
potato
family)
>70%
individuals.
Adolescent
pMR
was
associated
age
household
income,
replicating
prior
epidemiologic
findings.
Overall,
promises
an
objective
accurate
measure
types
plants
that
applicable
diverse
populations.
Trends in Food Science & Technology,
Год журнала:
2023,
Номер
134, С. 13 - 28
Опубликована: Фев. 8, 2023
Food
systems
worldwide
have
become
industrialized
over
the
past
century
with
impacts
on
diets,
nutrition
and
health.
The
trade-offs
between
affordability
higher-quality
diets
can
be
exemplified
by
industrially
produced,
refined
wheat
bread.
There
is
substantial
demand
for
designing
healthier
bread,
host-microbiota
commensalism
has
emerged
as
a
key
factor
in
food
product
development
aiming
to
deliver
health
benefits.
Based
pre-clinical
clinical
studies,
this
review
provides
an
overview
of
main
strategies
healthy
bread
from
microbiota
perspective.
We
also
discuss
how
microbiota-based
precision
harnessed
design
tailored
specific
individuals
or
populations.
In
addition
being
important
source
dietary
fiber
phytochemicals,
largest
contributor
intake
common
additives
countries
consuming
Western-like
ramifications
disease
via
gut
microbiota.
Pre-clinical
small-scale
studies
suggest
that
use
alternative
grains,
supplementation
induce
functional
properties
sourdough
fermentation
hold
great
potential
reducing
risk
factors
associated
diet-related
non-communicable
diseases
modulating
Nevertheless,
ingredients
formulated
may
need
applied
targeted
individual-specific
manner
expected
benefits
avoid
potentially
detrimental
consequences.
Overall,
we
identify
major
knowledge
gaps
research
opportunities
developing
gut-friendly
breads
scientifically
validated
Journal of Nutrition,
Год журнала:
2023,
Номер
153(7), С. 2004 - 2015
Опубликована: Фев. 22, 2023
The
Dietary
Guidelines
for
Americans
advises
on
dietary
intake
to
meet
nutritional
needs,
promote
health,
and
prevent
diseases.
Diet
affects
the
intestinal
microbiota
is
increasingly
linked
health.
It
vital
investigate
relationships
between
diet
quality
better
understand
impact
of
nutrition
human
health.This
study
aimed
differences
in
fecal
composition
adults
from
American
Gut
Project
based
their
adherence
Americans.This
was
a
cross-sectional
analysis
16S
sequencing
food
frequency
data
subset
(n
=
432;
age
18-60
y;
65%
female,
89%
white)
participating
crowdsourced
Project.
Healthy
Eating
Index-2015
assessed
compliance
with
Guideline
recommendations.
cohort
divided
into
tertiles
scores,
taxonomic
abundances
diversity
were
compared
high
low
scorers.The
mean
Total
Score
low-scoring
(58.1
±
5.4)
comparable
reported
score
average
adult
(56.7).
High
scorers
components
related
vegetables,
grains,
dairy
had
greater
alpha
than
scorers.
fatty
acid
component
lower
(95%
CI:
0.35,
1.85).
A
positive
log-fold
difference
abundance
plant
carbohydrate-metabolizing
taxa
families
Lachnospiraceae
Ruminococcaceae
observed
high-scoring
Score,
vegetable,
fruit,
grain
(Benjamini-Hochberg;
q
<
0.05).Adults
demonstrated
higher
bacteria
capable
metabolizing
complex
carbohydrates,
providing
evidence
how
support
gut
microbiota.
Biogeographic
variations
in
the
gut
microbiota
are
pivotal
to
understanding
global
pattern
of
host–microbiota
interactions
prevalent
lifestyle-related
diseases.
Pakistani
adults,
having
an
exceptionally
high
prevalence
type
2
diabetes
mellitus
(T2D),
one
most
understudied
populations
research
date.
The
aim
present
study
is
examine
across
individuals
from
Pakistan
and
other
non-industrialized
industrialized
lifestyles
with
a
focus
on
T2D.
fecal
samples
94
urban-dwelling
adults
without
T2D
were
profiled
by
bacterial
16S
ribosomal
RNA
gene
fungal
internal
transcribed
spacer
(ITS)
region
amplicon
sequencing
eubacterial
qPCR,
plasma
quantified
for
circulating
levels
lipopolysaccharide-binding
protein
(LBP)
activation
ability
Toll-like
receptor
(TLR)-signaling.
Publicly
available
datasets
generated
comparable
molecular
methods
retrieved
comparative
analysis
microbiota.
Overall,
urbanized
Pakistanis'
was
similar
that
transitional
or
populations,
depleted
Akkermansiaceae
enriched
Prevotellaceae
(dominated
non-Westernized
clades
Prevotella
copri).
relatively
proportion
Atopobiaceae
appeared
be
unique
characteristic
Pakistanis
had
elevated
LBP
TLR-signaling
circulation
as
well
microbial
signatures
atypical
e.g.,
increased
relative
abundance
Libanicoccus/Parolsenella,
limiting
inter-population
extrapolation
microbiota-based
classifiers
Taken
together,
our
findings
call
more
representation
extend
applicability
diagnostics
therapeutics.
Journal of Nutrition,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 1, 2025
Consuming
healthful
dietary
patterns
reduces
the
risk
of
developing
metabolic
diseases
and
nourishes
intestinal
microbiota.
Thus,
investigating
microbial
underpinnings
influences
on
health
is
clinical
interest.
To
determine
unique
contributions
fecal
taxa
metabolites
in
predicting
markers
adults
across
various
patterns.
Dietary,
metabolic,
microbiota
metabolome
data
from
118
(25-45y)
were
used
for
these
cross-sectional
analyses.
The
Diet
History
Questionnaire
II
assessed
adherence
to
Dietary
Approaches
Stop
Hypertension
(DASH),
Mediterranean
diet,
Mediterranean-DASH
Intervention
Neurocognitive
Delay
(MIND),
Healthy
Eating
Index-2020
(HEI-2020).
Metabolic
features
included
waist
circumference,
blood
pressure,
circulating
triglyceride
(TG),
high-density
lipoprotein
cholesterol
(HDL),
glucose
concentrations.
Microbiota
composition
was
via
16S
amplicon
sequencing
volatile
fatty
acid
bile
concentrations
measured
by
targeted
metabolomics.
ANCOM-BC2
correlation
analyses
screen
independently
associated
with
markers.
Then,
hierarchical
linear
regression
models
evaluate
select
beyond
HEI-2020
positively
richness
(p
=
0.02).
Beta
diversity
varied
all
<
0.05).
DASH
diet
scores,
[Eubacterium]
xylanophilum
abundance,
deoxycholic
(DCA)
concentration
explained
most
variance
systolic
(R2
0.32)
diastolic
0.26)
pressure
compared
other
features.
TG
best
predicted
MIND
[E].
eligens
isobutyrate
0.24).
Integrating
alongside
indices
improved
marker
prediction.
These
results
point
a
potential
role
underpinning
physiological
responses
highlight
biomarkers
health.
