Local 5-HT signaling bi-directionally regulates the coincidence time window for associative learning
Neuron,
Год журнала:
2023,
Номер
111(7), С. 1118 - 1135.e5
Опубликована: Янв. 26, 2023
Язык: Английский
Can insects feel pain? A review of the neural and behavioural evidence
Advances in insect physiology,
Год журнала:
2022,
Номер
unknown, С. 155 - 229
Опубликована: Янв. 1, 2022
Язык: Английский
Visual processing in the fly, from photoreceptors to behavior
Genetics,
Год журнала:
2023,
Номер
224(2)
Опубликована: Май 2, 2023
Abstract
Originally
a
genetic
model
organism,
the
experimental
use
of
Drosophila
melanogaster
has
grown
to
include
quantitative
behavioral
analyses,
sophisticated
perturbations
neuronal
function,
and
detailed
sensory
physiology.
A
highlight
these
developments
can
be
seen
in
context
vision,
where
pioneering
studies
have
uncovered
fundamental
generalizable
principles
processing.
Here
we
begin
with
an
overview
vision-guided
behaviors
common
methods
for
probing
visual
circuits.
We
then
outline
anatomy
physiology
brain
regions
involved
processing,
beginning
at
periphery
ending
descending
motor
control.
Areas
focus
contrast
motion
detection
optic
lobe,
circuits
feature
selectivity,
computations
support
spatial
navigation,
contextual
associative
learning.
Finally,
look
future
fly
neuroscience
discuss
promising
topics
further
study.
Язык: Английский
Aversive Bimodal Associations Differently Impact Visual and Olfactory Memory Performance in Drosophila
iScience,
Год журнала:
2022,
Номер
25(12), С. 105485 - 105485
Опубликована: Ноя. 3, 2022
Язык: Английский
Cognitive limits of larvalDrosophila: Testing for conditioned inhibition, sensory preconditioning and second-order conditioning
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Авг. 22, 2023
Abstract
Drosophila
larvae
are
an
established
model
system
for
studying
the
mechanisms
of
innate
and
simple
forms
learned
behaviour.
They
have
about
10
times
fewer
neurons
than
adult
flies,
it
was
low
total
number
their
that
allowed
electron
microscopic
reconstruction
brain
at
synaptic
resolution.
Regarding
mushroom
body,
a
central
structure
associative
learning
in
insects,
turned
out
more
half
classes
connection
had
previously
escaped
attention.
Understanding
function
these
circuit
motifs,
subsequently
confirmed
is
important
current
research
topic.
In
this
context,
we
test
larval
cognitive
abilities
three
tasks
characteristically
complex
those
studied.
Our
data
provide
evidence
(i)
conditioned
inhibition,
as
has
been
reported
flies
honeybees.
Unlike
what
described
honeybees,
however,
our
do
not
(ii)
sensory
preconditioning
or
(iii)
second-order
conditioning
larvae.
We
discuss
methodological
features
experiments
well
four
specific
aspects
organisation
may
explain
why
two
observed
honeybees
but
.
Язык: Английский
Aversive bimodal associations impact visual and olfactory memory performance in Drosophila
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2022,
Номер
unknown
Опубликована: Июль 23, 2022
Abstract
Insects
rely
heavily
on
sampling
information
from
their
environment
for
survival
and
fitness.
Different
sensory
channels
with
dedicated
downstream
neural
substrates
are
programmed
to
fine
tune
these
signals
translate
them
into
usable
instructions
mediate
complex
behaviors.
Sensory
can
also
be
learned
stored
as
memories
that
influence
decisions
in
the
future.
The
learning
of
unimodal
signals,
especially
olfaction,
has
been
studied
extensively
different
conditioning
paradigms
insects.
Using
Drosophila
melanogaster
model
our
work,
we
first
investigated
differences
efficiencies
aversive
associative
visual
olfactory
using
cues
innately
very
attractive,
such
blue
or
green
light
well
food
odors
found
fruits
yeast.
We
then
combined
presentation
stimuli
during
training
study
effect
bimodal
integration
performance.
When
trained
unimodally,
flies
did
not
easily
learn
stimuli,
but
when
bimodally,
they
developed
a
significant
short-term
memory
after
single
trial.
suppressed
phototaxis
response
near
abolishment.
However,
similar
enhance
some
cases,
even
caused
reduction
strength.
An
enhancement
was
only
seen
weak
long-term
retrieved
24h.
Our
demonstrates
is
always
synergistic,
conditional
upon
paradigm
inherent
abilities
modalities
involved.
Язык: Английский