Public health reviews, Год журнала: 2024, Номер 45
Опубликована: Май 20, 2024
Access to greenspaces and contact with nature can promote physical activity have positive effects on mental health. This scoping literature review aims examine current evidence linking (a) behaviour change, (b) health outcomes (c) co-benefits.
Язык: Английский
Allergy, Год журнала: 2021, Номер 76(11), С. 3390 - 3407
Опубликована: Авг. 15, 2021
Last year brought a significant advance in asthma management, unyielding to the pressure of pandemics. Novel key findings pathogenesis focus on resident cell compartment, epigenetics and innate immune system. The precision immunology unbiased approach was supplemented with novel tools greatly facilitated by use artificial intelligence. Several randomised clinical trials good quality real-world evidence shed new light treatment supported revision several guidelines (GINA, Expert Panel Report 3, ERS/ATS severe asthma) conception ones (EAACI Guidelines for biologicals asthma). Integrating management within broader context Planetary Health has been put forward. In this review, recently published articles are summarised discussed goal provide clinicians researchers concise update research from translational perspective.
Язык: Английский
Процитировано
127
Allergy, Год журнала: 2022, Номер 77(5), С. 1389 - 1407
Опубликована: Янв. 24, 2022
There is increasing understanding, globally, that climate change and increased pollution will have a profound mostly harmful effect on human health. This review brings together international experts to describe both the direct (such as heat waves) indirect vector-borne disease incidence) health impacts of change. These vary depending vulnerability (i.e., existing diseases) international, economic, political, environmental context. unique also expands these issues address third category potential longer-term global health: famine, population dislocation, justice education. scholarly resource explores fully, linking them in urban rural settings developed developing countries. The finishes with practical discussion action professionals around world our field can yet take.
Язык: Английский
Процитировано
110
Frontiers in Science, Год журнала: 2024, Номер 2
Опубликована: Апрель 4, 2024
Global warming and climate change have increased the pollen burden frequency intensity of wildfires, sand dust storms, thunderstorms, heatwaves—with concomitant increases in air pollution, heat stress, flooding. These environmental stressors alter human exposome trigger complex immune responses. In parallel, pollutants, allergens, other factors increase risks skin mucosal barrier disruption microbial dysbiosis, while a loss biodiversity reduced exposure to diversity impairs tolerogenic development. The resulting dysregulation is contributing an immune-mediated diseases such as asthma allergic diseases, autoimmune cancer. It now abundantly clear that multisectoral, multidisciplinary, transborder efforts based on Planetary Health One approaches (which consider dependence health environment natural ecosystems) are urgently needed adapt mitigate effects change. Key actions include reducing emissions improving quality (through fossil fuel use), providing safe housing (e.g., weatherization), diets (i.e., diversity) agricultural practices, increasing green spaces. There also pressing need for collaborative, multidisciplinary research better understand pathophysiology context New data science techniques, biomarkers, economic models should be used measure impact disease, inform mitigation adaptation efforts, evaluate their effectiveness. Justice, equity, diversity, inclusion (JEDI) considerations integral these address disparities
Язык: Английский
Процитировано
24
Environment International, Год журнала: 2021, Номер 157, С. 106811 - 106811
Опубликована: Авг. 14, 2021
In modern urban environments children have a high incidence of inflammatory disorders, including allergies, asthma, and type 1 diabetes. The underlying cause these according to the biodiversity hypothesis, is an imbalance in immune regulation caused by weak interaction with environmental microbes. this 2-year study, we analyzed bacterial community shifts soil surface day-care centers commensal bacteria inhabiting mouth, skin, gut children. We compared two different environments: standard intervention centers. Yards latter were amended biodiverse forest floor vegetation sod at beginning study. Intervention long-standing increase relative abundance nonpathogenic mycobacteria soils. Treatment-specific became evident composition Gammaproteobacteria, Negativicutes, Bacilli, which jointly accounted for almost 40 50% taxa on children's skin saliva, respectively. year-one swabs, richness Alpha-, Beta-, Gammaproteobacteria was higher, potentially pathogenic bacteria, Haemophilus parainfluenzae, Streptococcus sp., Veillonella lower among gut, Clostridium sensu stricto decreased, particularly This study shows that shapes human microbiota, been associated regulation. Results indicate enriched microbiota suppressed skin. recommend future studies expand strategies response eventually immune-mediated diseases.
Язык: Английский
Процитировано
70
Ecotoxicology and Environmental Safety, Год журнала: 2022, Номер 242, С. 113900 - 113900
Опубликована: Авг. 3, 2022
Язык: Английский
Процитировано
60
Scientific Reports, Год журнала: 2022, Номер 12(1)
Опубликована: Апрель 20, 2022
Abstract Urbanization reduces microbiological abundance and diversity, which has been associated with immune mediated diseases. Urban greening may be used as a prophylactic method to restore diversity in cities among urbanites. This study evaluated the impact of air-circulating green walls on bacterial human skin, responses determined by blood cytokine measurements. Human subjects working offices two Finnish (Lahti Tampere) participated two-week intervention, where were installed rooms experimental group. Control group worked without walls. Skin samples collected before (Day0), during (Day14) weeks after (Day28) intervention. The relative genus Lactobacillus Shannon phylum Proteobacteria class Gammaproteobacteria increased Proteobacterial was connected lower proinflammatory IL-17A level participants Lahti. In addition, change TGF-β1 levels opposite between control As skin are considered advantageous for health, induce beneficial changes microbiome. immunomodulatory potential deserves further research attention.
Язык: Английский
Процитировано
47
Allergy, Год журнала: 2023, Номер 78(7), С. 1777 - 1793
Опубликована: Апрель 29, 2023
Abstract The One Health approach is a collaborative and interdisciplinary strategy with focal point on human, animal, environmental health interconnections. can support the advanced management of allergic diseases asthma, as complex, multifactorial driven by interactions between resilience response to exposome. According concept asthma arising from exposures wide range allergens, infectious agents irritants (such pollutants) occurring indoors outdoors be heavily influenced (air, water, soil quality) intermingled animal health. These are currently impacted climate change, land use, urbanization, migration, overpopulation, many more. Thus, coordinated address underlying factors that contribute development needs focus environment, altogether. Collaborative efforts across multiple sectors, including public health, veterinary medicine, science, community engagement thus needed. A activities, monitoring surveillance data, targeted interventions reduce allergens irritants, research mechanisms drive needed move field forward. In this consensus document elaborated European Academy Allergy Clinical Immunology (EAACI) American Allergy, Asthma, (AAAAI) under practical allergy (PRACTALL) series, we provide insights into Heath aiming framework for addressing complex nature asthma.
Язык: Английский
Процитировано
25
People and Nature, Год журнала: 2024, Номер 6(3), С. 1078 - 1095
Опубликована: Апрель 24, 2024
Abstract Evidence suggests that soil microorganisms, to which humans have been exposed throughout our evolutionary history, were essential for the evolution of human gut microbiome and immunological resilience. In recent decades, microbial diversity has decreased along with urbanization global loss biodiversity. At same time, prevalence chronic, non‐communicable inflammatory diseases increasing in urbanized societies. Here, we investigate whether existing literature supports hypothesis ingesting microbiota provides We focus on identifying research gaps challenges must be overcome understand effects eating A scoping review peer‐reviewed empirical was carried out. The search focused studies mammals direct contact measured host response; 12 articles, including four human, six mouse two other mammal studies, identified inclusion review. addition, seven articles related health risks associated consumption included Studies indicate soil‐bound microorganisms There is a lack intervention include study subjects test orally effect Challenges, particularly heterogeneity biological chemical properties, prevented progress fully oral intake health. results encourage development technologies allow daily exposure microbiota. Future should aimed precisely importance homeostasis Read free Plain Language Summary this article Journal blog.
Язык: Английский
Процитировано
11
Journal of Inorganic and Organometallic Polymers and Materials, Год журнала: 2021, Номер 32(2), С. 513 - 535
Опубликована: Окт. 27, 2021
Язык: Английский
Процитировано
49
The Science of The Total Environment, Год журнала: 2022, Номер 821, С. 153422 - 153422
Опубликована: Янв. 25, 2022
Urbanization and biodiversity loss are linked to chronic disorders, in particular allergic diseases. The aim of this scoping review was provide a synopsis intervention studies specifically examining the influence exposure natural environments on human microbiota as well immunological markers suggested interlink between environment development We searched PubMed (MEDLINE®) all references cited included following PRISMA statement guidelines. No restrictions regarding age sex study participants, language or publication date were made. protocol registered at OSF REGISTRIES (https://osf.io/musgr). After screening, eight included. interventions reported mainly pilot character various, ranging from nature-related educational programs, day-cares short-term contact with soil- sand-preparations. Most studied appeared increase richness diversity specific taxa groups short-time. Immunological assessed only two studies. In these, their associations pre-dominantly reported. Conclusion: There is some evidence that so-called have potential diversify microbiota, least over short period. Adequately powered randomized controlled trials long term follow-up required examine sustainable effects immune system.
Язык: Английский
Процитировано
30