Elsevier eBooks, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Environmental Sciences Europe, Год журнала: 2024, Номер 36(1)
Опубликована: Фев. 6, 2024
Abstract Glyphosate (GLY), the most widely used herbicide active ingredient (AI) in world, is frequently detected aquatic environments where it can affect non-target organisms. Globally, more than 2000 commercial GLY-based herbicides (GBHs) are to control weeds. Non-target organisms exposed complex pesticide formulations under real environmental conditions, but co-formulants contained GBHs classified as so-called inert and inactive ingredients terms of their biological effects. The main objective this comprehensive review compile results ecotoxicological studies on side-effects GLY, GBHs, formulating agents. Based demonstrated for a variety plant animal organisms, oxidative stress appears be major trigger these adverse effects, affecting integrity DNA other biochemical functions. Furthermore, there evidence impairment various physiological behavioral Adverse effects GLY have been observed even at very low concentrations. There also differences sensitivity tested, with similar lifestyles, habitats or identical taxa. typically investigate short-term single exposure GLY/GBH species, whilst reality multiple applications together pesticides common during cropping cycle. Moreover, interactions between GLY/GBHs contaminants rarely studied. Higher toxicity compared alone has often observed, demonstrating that highly toxic own markedly increase GBH formulation. possible impurities such heavy metals, cause additional problems environment food safety. widespread massive use leads increased hazards. In addition, need revision risk assessment system emphasized. According studies, current pollution by problematic cannot considered environmentally sustainable. It is, therefore, necessary least tighten permitted forms use.
Язык: Английский
Процитировано
20
Trends in Ecology & Evolution, Год журнала: 2022, Номер 37(9), С. 789 - 802
Опубликована: Июнь 16, 2022
Wildlife are exposed to an increasing number and diversity of chemical pollutants.Chemical pollutants can elicit a range sublethal effects on individual organisms, but research how these contaminants affect social interactions animal groups is severely lacking.It imperative that perspectives from behavioural ecology ecotoxicology integrated, increase our understanding contaminant individuals might cascade group-level processes.We present conceptual framework for researchers practitioners guide the study emergence, organisation, function groups. Chemical pollution among fastest-growing agents global change. Synthetic chemicals with diverse modes-of-action being detected in tissues wildlife pervade entire food webs. Although such lacking. Here we synthesise two related, largely segregated fields – examine pathways by which could disrupt processes govern self-organisation, collective Our review provides roadmap prioritising within context sociality highlights important methodological advancements future research. Pollution arising production consumption synthetic now outpaces other environmental megatrends (e.g., rising CO2 emissions [1.Bernhardt E.S. et al.Synthetic as change.Front. Ecol. Environ. 2017; 15: 84-90Crossref Scopus (377) Google Scholar]). Increasing human reliance, coupled world population growth insufficient regulation, has driven exponential rise products marketed globally (>350 000 [2.Wang Z. al.Toward pollution: first comprehensive analysis national regional inventories.Environ. Sci. Technol. 2020; 54: 2575-2584Crossref PubMed (332) Scholar]), corresponding surge infiltrating environment [3.Landrigan P.J. al.Pollution health agenda prevention.Environ. Health Perspect. 2018; 126084501Crossref (52) Scholar]. Ecosystems worldwide staggering array compounds agrochemicals [4.Tang F.H.M. al.Risk pesticide at scale.Nat. Geosci. 2021; 14: 206-210Crossref (293) Scholar] metals [5.Briffa J. al.Heavy metal their toxicological humans.Heliyon. 6e04691Abstract Full Text PDF (1161) Scholar], pharmaceuticals [6.Wilkinson J.L. al.Pharmaceutical world's rivers.Proc. Natl. Acad. U. S. A. 2022; 119e2113947119Crossref (328) personal care [7.Dey al.1 - Pharmaceuticals product (PPCP) contamination—a discharge inventory.in: Prasad M.N.V. Personal Care Products: Waste Management Treatment Technology. Butterworth-Heinemann, 2019: 1-26Crossref (84) Many degrade slowly remain highly persistent environment, while others released near-constant rate thus considered be 'pseudo-persistent'. Consequently, have been wide [8.Li Y. al.Neonicotinoids decline bird biodiversity United States.Nat. Sustain. 3: 1027-1035Crossref (70) Scholar,9.Garcia-Cegarra A.M. al.Persistence, bioaccumulation vertical transfer long-finned pilot whales stranded Chilean Patagonia.Sci. Total 770145259Crossref (8) pervading webs [10.Richmond E.K. al.A suite contaminates stream riparian webs.Nat. Commun. 9: 1-9Crossref (165) Scholar,11.Yamamuro M. aquatic decrease fishery yields.Science. 2019; 366: 620-623Crossref (145) A wealth dating back Rachel Carson's seminal 1962 publication Silent Spring [12.Carson R. Spring. Fawcett Publications, 1962Google documented adverse impacts wildlife. Besides causing mortality acutely lethal levels, animals, even minute concentrations including disrupting behaviour. Such may hidden drivers declines ecological instability [13.Saaristo al.Direct indirect behaviour, evolution wildlife.Proc. Soc. B Biol. 28520181297PubMed fuelling calls better integration indicators into risk assessment [14.Ford A.T. al.The role behavioral protection.Environ. 55: 5620-5628Crossref (83) However, nearly all (see Glossary) focused behaviours little consideration emergent group functions. This critical oversight because many animals engage over lifetime live structured societies or form loosely (Figure 1). These coordinate conspecifics provide protection against predation, gain reproductive opportunities, find food, reduce energy expenditure [15.Krause al.Living Groups. Oxford University Press, 2002Google Collective behaviour directly affects both fitness. Here, novel outlines instrumental emergence self-organisation We formulate predictions disruptions ultimately outcomes, detail themselves exacerbate buffer contamination, species Importantly, presents timely opportunity integrate key step towards improving threat posed influence impacting units compose (i.e., individuals) and/or those sociality). manifest across local spatial scales change formation 2, Key figure ). integrates mechanisms underlie different types systems, dynamic fission–fusion relatively stable To predict groups, need understand they environmentally realistic exposure levels. Documented severe physiological physical impairment, subtler not stress escape response. focus examples cascading implications level (Box 1).Box 1Can make generalised certain classes will impact groups?Chemical unique challenge due sheer classes, existence numerous between classes. The species-specific, contingent several factors, degree homology non-target intended target species. Further, do primary mode-of-action conventionally associated disruption antibiotics, antihistamines), specifically designed metals, surfactants), yet still so. makes generating difficult. biological targets, disruption, general valuable directing studies sociality. In Table I, outline series individual-level induced expected consequences, identify predicted induce effects.Table IGeneral consequencesIndividual-level effectsChemical classesaFor each class, use example subgroup narrow specific targets. class 1–8.Group formationGroup dynamicsRefsAntisocial behaviour1,2,3,4,5Reduced tendency accept Higher rejection potential members.Increased conflict amongst members weaker networks. Altered structure.[33.Whitlock S.E. al.Environmentally relevant antidepressant alters courtship songbird.Chemosphere. 211: 17-24Crossref (18) Scholar,34.Hubená P. al.Prescribed aggression fishes: modify concentrations.Ecotoxicol. Saf. 227112944Crossref Scholar,92.Santos M.E.S. al.Traces tramadol water native European fish.Ecotoxicol. 212111999Crossref (9) Scholar, 93.Brodin T. al.Dilute psychiatric drug alter behavior fish natural populations.Science. 2013; 339: 814-815Crossref (602) 94.Fenske L. al.17-α-Ethinylestradiol modulates endocrine responses zebrafish.Environ. Pollut. Res. Int. 27: 29341-29351Crossref (14) Scholar]Reduced anxiety perception1,2,6Decrease propensity join (particularly if grouping primarily antipredator strategy).Slow response times actions. Less coordination cohesion. risk-taking poorer predator evasion.[30.Cerveny D. al.Bioconcentration four benzodiazepines mixture wild fish.Sci. 702134780Crossref (20) Scholar,57.Martin J.M. psychoactive pollutant fluoxetine compromises fish.Environ. 222: 592-599Crossref (90) Scholar,93.Brodin Scholar]Hyperactivity3,4Higher interaction rates, lower capacity adjust formation.Faster movement, altering cohesion polarisation. Hyperactive rejected unimpaired groups.[95.Horký al.Methamphetamine elicits addiction fish.J. Exp. 224jeb242145Crossref (23) Scholar,96.De Serrano A.R. al.Paternal common pharmaceutical (Ritalin) transgenerational Trinidadian guppies.Sci. Rep. 11: 3985Crossref (6) Scholar]Lower activity/compromised locomotion1,5,6,7,8Inability impaired join, move between, groups.Slower Impaired likely groups.[42.Eng M.L. al.Imidacloprid chlorpyrifos insecticides impair migratory ability seed-eating songbird.Sci. 7: 15176Crossref (105) Scholar,97.Ložek F. al.Behaviour cardiac signal crayfish tramadol.Aquat. Toxicol. 213105217Crossref (17) 98.Almeida C.H.S. al.Sublethal agrochemical exposures honey bees' neotropical stingless color preferences, respiration locomotory responses.Sci. 779146432Crossref 99.Bachour R.-L. al.Behavioral citalopram, tramadol, binary zebrafish (Danio rerio) larvae.Chemosphere. 238124587Crossref (39) 100.Matus G.N. al.Behavior histopathology biomarkers evaluation paracetamol propranolol Phalloceros harpagos.Environ. 25: 28601-28618Crossref Scholar]Altered cognition4,7,8Reduced process information cues formation.Reduced competence inappropriate partners. Poorer decision-making coordination.[16.Bókony V. al.Effects little-studied early development anurans.Environ. 260114078Crossref (15) Scholar,95.Horký Scholar,101.Siviter H. al.Quantifying pesticides learning memory bees.J. Appl. 2812-2821Crossref (94) Scholar]Sensory disruption3,8Inability attract discriminate members. Reduced assortment.Poor communication Uncoordinated increased failure actions.[20.Besson al.Anthropogenic stressors sensory survival via thyroid disruption.Nat. 1-10Crossref (26) Scholar,23.Ankley G.T. androgenic promoter 17-β-trenbolone fecundity endocrinology fathead minnow.Environ. Chem. 2003; 22: 1350-1360Crossref Scholar,60.Tomkins al.An endocrine-disrupting agricultural sequential female mate choice 237: 103-110Crossref (28) Scholar]1-Antidepressants selective serotonin reuptake inhibitors)2- Anxiolytics benzodiazepines)3-Steroids androgens)4- Psychostimulants central nervous system stimulants)5- Analgesics opioids)6- Beta-blockers nonselective blockers)7- Anticonvulsants dibenzazepines)8- Insecticides neonicotinoids)a For 1–8. Open table new tab 1-Antidepressants inhibitors) 2- benzodiazepines) 3-Steroids androgens) 4- stimulants) 5- opioids) 6- blockers) 7- dibenzazepines) 8- neonicotinoids) Exposure lead dramatic morphological alterations, changes body size [16.Bókony colouration [17.Chatelain al.Do trace visual signals? Effects iridescent melanic feather feral pigeon.Oikos. 126: 1542-1553Crossref sex [18.Kidd K.A. al.Collapse after estrogen.Proc. 2007; 104: 8897-8901Crossref (1577) Perhaps most fundamental interfere anatomy involved visual, auditory, olfactory, tactile senses). Various surfactants pesticides, herbicides damage chemoreceptors olfactory [19.Razmara al.Mechanism copper nanoparticle toxicity rainbow trout mucosa.Environ. 284117141Crossref (13) Scholar,20.Besson amphibians [21.Sievers al.Contaminant mixtures interact predator-avoidance larval amphibian.Ecotoxicol. 161: 482-488Crossref (44) insects [22.Williamson S.M. Wright G.A. multiple cholinergic impairs honeybees.J. 216: 1799-1807PubMed greatly reducing detect cues. extreme cases, anatomy. instance, minnows, Pimephales promelas, 17β-trenbolone developed nuptial tubercles, structures typically only found males [23.Ankley Beyond abnormalities, often causes physiological, neurological, hormonal leading phenotypic expression [24.Goodchild C.G. al.Male zebra finches (Pb) during reduced volume song nuclei, altered sexual traits, received less attention females adults.Ecotoxicol. 210111850Crossref 25.Yamindago al.Fluoxetine neurotransmission systems animals.Ecotoxicol. 227112931Crossref (10) 26.Straub al.Negative neonicotinoids male honeybee survival, physiology field.J. 58: 2515-2528Crossref individual's metabolic state, foraging activity [27.Tan al.Chronic pervasive erodes among-individual variation 263114450Crossref Changes neurological cognitive occur when mimic block actions neurotransmitters, neurohormones, steroid hormones modulate [28.Vaudin al.When drugs become pollutants: neural underlying mechanisms.Environ. 205112495PubMed also receptors signalling molecules, functionality enzymes, modulation transmission de- hyperpolarisation [29.Richardson J.R. al.Neurotoxicity pesticides.Acta Neuropathol. 138: 343-362Crossref (211) Pollutants stemming medications, behaviours, [30.Cerveny Scholar,31.Buřič citalopram invertebrate.Aquat. 200: 226-232Crossref (50) Scholar,32.Chabenat al.Alteration predatory gro
Язык: Английский
Процитировано
46
Environment International, Год журнала: 2024, Номер 187, С. 108703 - 108703
Опубликована: Апрель 26, 2024
Poly- and perfluoroalkyl substances (PFAS) are frequently detected in the environment linked to adverse reproductive health outcomes humans. Although legacy PFAS have been phased out due their toxicity, alternative increasingly used despite fact that information on toxic effects traits is particularly scarce. Here, we exposed male guppies (Poecilia reticulata) for a short period (21 days) an environmentally realistic concentration (1 ppb) of PFOA, PFAS, its replacement compound, GenX, assess impact gene expression. Exposure did not impair survival but instead caused sublethal effects. Overall, exposure changes sexual behaviour had detrimental sperm motility. Sublethal variations were also seen at transcriptional level, with modulation genes involved immune regulation, spermatogenesis, oxidative stress. We observed bioaccumulation which was higher PFOA than GenX. Our results offer comprehensive comparison these two shed light toxicity newly emerging PFAS. It therefore evident even low concentrations exposure, can subtle yet significant behaviour, fertility, immunity. These findings underscore potential ramifications pollution under natural conditions fish populations.
Язык: Английский
Процитировано
12
Pesticide Biochemistry and Physiology, Год журнала: 2024, Номер 199, С. 105800 - 105800
Опубликована: Янв. 28, 2024
Язык: Английский
Процитировано
9
PLoS Biology, Год журнала: 2024, Номер 22(1), С. e3002478 - e3002478
Опубликована: Янв. 30, 2024
Biological rhythms have a crucial role in shaping the biology and ecology of organisms. Light pollution is known to disrupt these rhythms, evidence emerging that chemical pollutants can cause similar disruption. Conversely, biological influence effects toxicity chemicals. Thus, by drawing insights from extensive study biomedical light research, we greatly improve our understanding pollution. This Essay advocates for integration rhythmicity into research gain more comprehensive how affect wildlife ecosystems. Despite historical barriers, recent experimental technological advancements now facilitate ecotoxicology, offering unprecedented, high-resolution data across spatiotemporal scales. Recognizing importance will be essential understanding, predicting, mitigating complex ecological repercussions
Язык: Английский
Процитировано
8
Ecology Letters, Год журнала: 2025, Номер 28(2)
Опубликована: Фев. 1, 2025
ABSTRACT How societal, ecological and infrastructural attributes interact to influence wildlife movement is uncertain. We explored whether neighbourhood socioeconomic status environmental quality were associated with coyote ( Canis latrans ) patterns in Los Angeles, California assessed the performance of integrated social–ecological models. found that coyotes living more anthropogenically burdened regions (i.e. higher pollution, denser development, etc.) had larger home ranges showed greater daily displacement mean step length than less regions. Coyotes experiencing differing levels anthropogenic burdens demonstrated divergent selection for vegetation, road densities other habitat conditions. Further, models included societal covariates performed better only features linear infrastructure. This study provides a unique lens examining drivers urban movement, which should be applicable planners conservationists when building equitable, healthy wildlife‐friendly cities.
Язык: Английский
Процитировано
1
Toxics, Год журнала: 2022, Номер 10(5), С. 233 - 233
Опубликована: Май 3, 2022
There is a growing concern that neuroactive chemicals released into the environment can perturb wildlife behaviour. Among these chemicals, pharmaceuticals such as antidepressants and anxiolytics have been receiving increasing attention, they are specifically prescribed to modify behavioural responses. Many laboratory studies demonstrated some of compounds affect various aspects behaviour range aquatic organisms; however, investigations focused on very small set pharmaceuticals, often consider one compound at time. In this study, better understand environmental toxicological dimension problem, we considered all explicitly intended modulate central nervous system (CNS), hypothesised higher probability perturbing animal Based hypothesis, used classification provided by British National Formulary (based their clinical applications) identified 210 different CNS-acting in UK treat variety CNS-related conditions, including mental health sleep disorders, dementia, epilepsy, nausea, pain. The analysis existing databases revealed 84 were already detected surface waters worldwide. Using biological read-across approach based extrapolation data, predicted concentration 32 England may be high enough elicit pharmacological effects wild fish. ecotoxicological vast majority currently uncharacterised. Overall, results highlight importance addressing challenge from mixture toxicology systems perspective. knowledge platform developed present study guide future region-specific prioritisation efforts, inform design studies, foster interdisciplinary efforts aimed identifying novel approaches predict interpret ecological implications chemical-induced disruption.
Язык: Английский
Процитировано
30
ACS Infectious Diseases, Год журнала: 2024, Номер 10(4), С. 1026 - 1033
Опубликована: Март 27, 2024
Parasitic vector-borne diseases (VBDs) represent nearly 20% of the global burden infectious diseases. Moreover, spread VBDs is enhanced by travel, urbanization, and climate change. Treatment faces challenges due to limitations existing drugs, as potential for side effects in nontarget species raises significant environmental concerns. Consequently, considering risks early drug development processes critically important. Here, we examine risk assessment process veterinary medicinal products European Union identify major gaps ecotoxicity data these drugs. By highlighting scarcity ecotoxicological commonly used antiparasitic stress urgent need One Health concept. We advocate employing predictive tools nonanimal methodologies such New Approach Methodologies at stages research development. Furthermore, adopting progressive approaches mitigate ecological requires integration nonstandard tests that account real-world complexities use environmentally relevant exposure scenarios. Such a strategy vital sustainable it adheres principles Health, ultimately contributing healthier more world.
Язык: Английский
Процитировано
7
The Science of The Total Environment, Год журнала: 2024, Номер 917, С. 170405 - 170405
Опубликована: Янв. 26, 2024
The functional conservation of important selective serotonin reuptake inhibitor (SSRI) targets in non-target organisms raises concerns about their potential adverse effects on the ecosystems. Although environmental levels SSRIs like paroxetine (PAR) have risen, knowledge regarding long-term exposure to PAR is limited. This study investigated impact sub-chronic (21 days) two sub-lethal concentrations (40 and 400 μg/L) behaviour adult zebrafish different scenarios: basal activity (under dark light conditions), stress response (evoked by sudden transitions) recovery. A new framework was employed for integrative fish's swimming performance based innate ability respond shifts. Several swimming-associated parameters (e.g., total distance, time inactivity, angles) thigmotaxis were monitored an integrated analysis each scenario. Data revealed reduced activity, impaired behavioural alterations recovery PAR-exposed fish. An anxiolytic effect particularly noticeable fish at μg/L (from light) dark) exposed 40 μg/L. detected PAR-induced modifications suggest a disruption brain glucocorticoid signalling that may implications individual level changing responses predators), with repercussions population community levels. Therefore, applied protocol proved sensitive detecting changes induced PAR.
Язык: Английский
Процитировано
6
The Science of The Total Environment, Год журнала: 2024, Номер 918, С. 170793 - 170793
Опубликована: Фев. 7, 2024
Язык: Английский
Процитировано
6