MODULATION OF IMMUNITY AND BARRIER FUNCTION IN PRE- AND POSTNATAL ANIMAL ONTOGENESIS. PHYSIOLOGICAL ASPECTS OF NATURAL RESISTANCE IN SOWS DOI Open Access
D. М. Masiuk, V. S. Nedzvetsky, А. В. Кокарєв

и другие.

Опубликована: Янв. 1, 2023

The main task for the effective breeding of productive animals is obtaining viable offspring and ensuring appropriate functional status organism during all stages ontogenesis 1 .The most important while development a period early postnatal adaptation 234 .In Ukrainian pig farms, this time one periods when high percentage neonatal piglet mortality observed 5 .One reasons problem caused with non-infectious pathology digestive respiratory tracts 6 .This due to low level innate immunity increase some technological limitations, stress induced by various etiologic factors, disruptions in technology rearing sow.The combined effect these factors leads destruction fetal development, lack colostrum quality, accompanied immunodeficiency changes newborn piglets 7 .1 Oster, M.

Язык: Английский

Progressively differentiated TFH13 cells are stabilized by JunB to mediate allergen germinal center responses DOI
Pragya Chandrakar, Cody S. Nelson,

Manuel Alfredo Podestà

и другие.

Nature Immunology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 31, 2025

Язык: Английский

Процитировано

0
Novel therapeutic receptor agonists and antagonists in allergic conjunctivitis DOI
Sampson Listowell Abu,

Navpreet K. Hehar,

DeGaulle I. Chigbu

и другие.

Current Opinion in Allergy and Clinical Immunology, Год журнала: 2024, Номер 24(5), С. 380 - 389

Опубликована: Июль 22, 2024

Allergic conjunctivitis is characterized by the development of pathophysiological changes to ocular surface, which occurs when pro-allergic and pro-inflammatory mediators interact with their cognate receptors expressed on immune nonimmune cells. Traditional treatments antihistamines corticosteroids provide relief, but there a need for more efficacious tolerable long-term therapy better safety profile. This article aims an overview mode action clinical application agonist therapies targeting glucocorticoid, melanocortin, toll-like receptors, as well antagonist cytokine, chemokine, integrin, histamine receptors.

Язык: Английский

Процитировано

2
MODULATION OF IMMUNITY AND BARRIER FUNCTION IN PRE- AND POSTNATAL ANIMAL ONTOGENESIS. PHYSIOLOGICAL ASPECTS OF NATURAL RESISTANCE IN SOWS DOI Open Access
D. М. Masiuk, V. S. Nedzvetsky, А. В. Кокарєв

и другие.

Опубликована: Янв. 1, 2023

The main task for the effective breeding of productive animals is obtaining viable offspring and ensuring appropriate functional status organism during all stages ontogenesis 1 .The most important while development a period early postnatal adaptation 234 .In Ukrainian pig farms, this time one periods when high percentage neonatal piglet mortality observed 5 .One reasons problem caused with non-infectious pathology digestive respiratory tracts 6 .This due to low level innate immunity increase some technological limitations, stress induced by various etiologic factors, disruptions in technology rearing sow.The combined effect these factors leads destruction fetal development, lack colostrum quality, accompanied immunodeficiency changes newborn piglets 7 .1 Oster, M.

Язык: Английский

Процитировано

0