Effectiveness of nonsurgical re‐instrumentation of residual pockets as step 3 of periodontal therapy: A field study

Journal of Periodontology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 18, 2025

Abstract Background The study aims to analyze the effectiveness of nonsurgical re‐instrumentation residual pockets as step 3 periodontal therapy and stability treatment outcomes at 18 months. Methods sample consisted 489 patients diagnosed treated nonsurgically for periodontitis. After a 6‐month evaluation, (≥5 mm) were re‐instrumented. A final examination was performed Participants categorized by outcome 6 months: (A) No ≥5 mm, (B) Residual 5–6 or (C) ≥7 mm. primary pocket closure (≤4 mm). Logistic regression models built evaluate initial Results Re‐instrumentation 5 mm resulted in around 39% groups B C. corresponding result sites with deeper pocketing (probing depth [PPD] 28%. Combining hand ultrasonic instrumentation more effective than each alone. Healed (6 months) likely remain closed group (80%) (50%) C (40%). logistic revealed that 1 2 influenced PPD baseline, tobacco smoking, age, type tooth. Conclusions At 3, can effectively improve health conditions. Treatment decisions after should be based on probing depth, overall healing response, patient behavior. clinical results disease severity therapy. Plain Language Summary This examined re‐treatment (periodontal not healed) involved periodontitis (loss tooth‐supporting structures) general dental practice. re‐treated gingival successful moderately diseased compared most severely pockets. Clinical achieved mild form better terms suffering from moderate severe success start, tooth affected, age patient, whether smoker not.

Язык: Английский

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Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, Год журнала: 2025, Номер unknown

Опубликована: Фев. 14, 2025

Periodontitis is a complex inflammatory disease in which the host genome, conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition strongest risk factor first decades of life. As people age, chronic exposure to periodontal microbiome puts strain on proper maintenance barrier function. This review summarizes our current knowledge genetic factors implicated periodontitis, derived (i) from hypothesis-free systematic whole genome-profiling studies (genome-wide association [GWAS] quantitative trait loci [QTL] mapping studies), independently validated through further unbiased approaches; (ii) monogenic oligogenic forms periodontitis; (iii) syndromic periodontitis. The genes include, but are not limited to, SIGLEC5, PLG, ROBO2, ABCA1, PF4, CTSC. Notably, CTSC PLG gene mutations were also identified non-syndromic prepubertal early-onset functions this suggest that pathways affected by periodontitis-associated variants converge involved repair structural integrity tissues. Particularly, these play role healing inflamed ulcerated tissues, including roles fibrinolysis, extrusion cellular debris, extracellular matrix remodeling angiogenesis. Syndromes include periodontitis their phenotype indicate neutrophils an important regulation inflammation periodontium. established therefore collectively provide new insights into molecular mechanisms plausible causal underlying

Язык: Английский

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Clinical and microbiological efficiencies of indocyanine green-mediated photodynamic therapy and Laser curettage as adjunct to nonsurgical periodontal therapy for treatment of stage 3 periodontitis: a randomized clinical trial

Lasers in Dental Science, Год журнала: 2025, Номер 9(1)

Опубликована: Фев. 19, 2025

Язык: Английский

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Awareness of Physicians about the Relationship of Periodontal Diseases and Systemic Conditions in Nashik District: A Questionnaire Study

Advances in Human Biology, Год журнала: 2025, Номер unknown

Опубликована: Март 4, 2025

Abstract Introduction: Periodontitis is a multifactorial chronic inflammatory illness affecting teeth, leading to tooth loss and recession. It major public health concern, diabetes, osteoporosis, cardiovascular disease pregnancy. Medical professionals should prioritise treating periodontitis improve systemic illnesses, as it significantly impacts overall health. Materials Methods: A self-structured questionnaire pilot study consisting of 13 questions was conducted evaluate the awareness physicians regarding relationship between periodontal diseases conditions. total 179 participated, data were then put statistical analysis. Results: On performing descriptive statistics, majority (95.5%) knew there some general body health, while 88.8% examined oral cavity patient upon examining Further, 95% referred them dentist when they found an abnormality. Conclusion: This denotes significant interrelationships among Nashik district but demands more targeted efforts in regions this two-way relationship.

Язык: Английский

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New tendencies in non-surgical periodontal therapy

Brazilian Oral Research, Год журнала: 2021, Номер 35(suppl 2)

Опубликована: Янв. 1, 2021

The aim of this review was to update the evidence new approaches non-surgical therapy (NSPT) in treatment periodontitis. Preclinical and clinical studies addressing benefits adjunctive antimicrobial photodynamic therapy, probiotics, prebiotics/synbiotics, statins, pro-resolving mediators, omega-6 -3, ozone, epigenetic were scrutinized discussed. Currently, outcomes these nine approaches, when compared with subgingival debridement alone, did not demonstrate a significant added benefit. However, some alternative interventions may have potential improve NSPT alone. Future based on randomized controlled trials would help clinicians patients selection different therapies.

Язык: Английский

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Outcome measures to assess the effectiveness of endodontic treatment for pulpitis and apical periodontitis for use in the development of European Society of Endodontology (ESE) S3 level clinical practice guidelines: a protocol

International Endodontic Journal, Год журнала: 2021, Номер 54(5), С. 646 - 654

Опубликована: Фев. 25, 2021

The European Society of Endodontology (ESE) is in the process developing S3Level Clinical Practice Guidelines for treatment pulpal and apical disease benefit clinicians patients. In order to ensure a homogenous review development clinical practice guidelines, it essential that core outcomes all endodontic treatments are standardized recommendations made regarding minimum follow-up time specific each outcome measure. absence recognized set Endodontics, current project aimed follow an established consensus define most appropriate clinician patient-reported outcomes. As part project, will also be agreed acceptable period studies by literature group discussion. selected measures periods used subsequent systematic analyses investigate effectiveness alleviate pulpitis periodontitis. this paper, previous reviews, ESE Position Statements were searched compile list potentially important (working 1), nonsurgical periodontitis 2), surgical 3) regenerative 4). Initially, two S3 guideline leads independent senior academics with experience evidence-based dentistry lead four working groups forming 10-member steering group. turn 32 individual reviews contained within respective groups. These 42 individuals make up Guideline Development Group (GDG). Prior reviewers commencing writing submitting protocol, complete variables identified document ranked members GDG their importance patient using 9-point Likert scale. A summary survey scores thereafter shared final rated as critical decision making (7-9 on scale majority participants) guide consented confirmed during online meeting meeting, another aspect regard meaningfulness trial results addressed consented: length follow-up. develop high quality suggested after should related measure being addressed; however, one year assessing considered. It accepted, research questions focus pain, swelling, medication taken or investigating diagnostic accuracy likely have shorter periods. result process, will, alongside use standard instruments assess methodological trials other comparative studies, applied commissioned inform when Level Guidelines.

Язык: Английский

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Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri-implant diseases

Cochrane library, Год журнала: 2024, Номер 2024(8)

Опубликована: Июль 12, 2024

Язык: Английский

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Active gingival inflammation is linked to hypertension

Journal of Hypertension, Год журнала: 2020, Номер 38(10), С. 2018 - 2027

Опубликована: Июнь 22, 2020

Cardiovascular diseases (CVD) including hypertension, are characterized by underlying systemic inflammation. Periodontitis, which can impact the inflammatory burden has recently been linked to high blood pressure (BP). However, relationship of gingival bleeding, as an easily accessible marker periodontal disorder, with remains unclear.Survey-based propensity score matching (PSM) incorporating major confounders shared between hypertension and was applied cross-sectional NHANES III data from 5396 adults at least 30 years old who underwent BP measurement examination, identifying two matched groups without bleeding. The association bleeding gums SBP (mmHg) high/uncontrolled then assessed generalized additive models markers. Stratification status (healthy; gingivitis; stable periodontitis; unstable periodontitis) performed. Variables importance estimated using machine learning.Gingival (gingivitis; independently associated +2.6 mmHg (P < 0.001) compared no (healthy periodontium; periodontitis), greater odds (OR = 1.42; 95% CI 1.19-1.68; P BP. Participants periodontitis had higher than those (+2.1 mmHg; or gingivitis (+5.3 0.001). Unstable were consistently increased risk 1.65, 2.14-1.82; OR 1.49, 1.22-1.82, respectively). Inflammatory markers allowed a maximum 12% gain in models' predictive power.Gingival contributes shaping BP, but represented is also crucial. Periodontal evaluation might be difficult control hypertension.

Язык: Английский

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Treatment of Residual Periodontal Pockets Using a Hyaluronic Acid-Based Gel: A 12 Month Multicenter Randomized Triple-Blinded Clinical Trial

Antibiotics, Год журнала: 2021, Номер 10(8), С. 924 - 924

Опубликована: Июль 30, 2021

The aim of the present study was to evaluate adjunctive effect hyaluronic acid (HA) gel in treatment residual periodontal pockets over a 12-month period. Periodontal patients presenting at least one pocket 5–9 mm depth anterior area were recruited from six university-based centers. Each patient randomly assigned subgingival instrumentation (SI) with local use HA for test or placebo control baseline and after 3 months. Clinical parameters ( )probing (PD), bleeding on probing (BoP), plaque index (PI), recession (REC), clinical attachment level (CAL)) microbiological samples investigation total bacterial count (TBC) presence specific species (Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Fusobacterium nucleatum) taken every months, until termination. PD determined as primary outcome variable. From 144 enrolled, 126 participants (53 males, 73 females) completed entire protocol. Both treatments resulted statistically significant improvements compared baseline. Although application showed tendency better results, there lack differences between groups.

Язык: Английский

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Prevention and management of peri‐implant mucositis and peri‐implantitis: A systematic review of outcome measures used in clinical studies in the last 10 years

Journal Of Clinical Periodontology, Год журнала: 2022, Номер 50(S25), С. 55 - 66

Опубликована: Март 5, 2022

To evaluate outcome measures, methods of assessment, and analysis in clinical studies on the prevention management peri-implant mucositis peri-implantitis.Systematic electronic searches (CENTRAL/MEDLINE/SCOPUS) up to April 2021 were conducted identify longitudinal with ≥10 patients either or diseases. Outcome measures this choice analytical methods. Risk bias was evaluated according study design. Data extracted into evidence tables outcomes analysed a descriptive manner.The 159 selected revealed that probing pocket depth (PPD) bleeding/suppuration (BOP) reported 89% 87% all studies, respectively. Additional included plaque scores (reported 64% studies), radiographic (49%), soft tissue dimensions (34%), composite (26%). Adverse events (8%) patient-reported (6%) only rarely mentioned. A primary measure clearly defined 36% studies. PPD, outcomes, primarily as mean values frequency distributions. For dimensions, it frequently unclear how clustered data handled.PPD BOP routinely peri-implantitis, while adverse events, infrequently described.

Язык: Английский

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