ACS Nano,
Год журнала:
2024,
Номер
18(31), С. 20027 - 20054
Опубликована: Июль 29, 2024
Magnetically
responsive
soft
smart
materials
have
garnered
significant
academic
attention
due
to
their
flexibility,
remote
controllability,
and
reconfigurability.
However,
traditional
used
in
the
construction
of
these
magnetically
systems
typically
exhibit
low
density
poor
thermal
electrical
conductivities.
These
limitations
result
suboptimal
performance
applications
such
as
medical
radiography,
high-performance
electronic
devices,
management.
To
address
challenges,
gallium-based
liquid
metals
emerged
promising
alternatives.
In
this
review,
we
summarize
methodologies
for
achieving
metals,
including
integration
magnetic
agents
into
metal
matrix
utilization
induced
Lorentz
forces.
We
then
provide
a
comprehensive
discussion
key
physicochemical
properties
factors
influencing
them.
Additionally,
explore
advanced
potential
metals.
Finally,
discuss
current
challenges
field
present
an
outlook
on
future
developments
research
directions.
Advanced Materials,
Год журнала:
2024,
Номер
36(19)
Опубликована: Янв. 30, 2024
Soft
actuators
(SAs)
are
devices
which
can
interact
with
delicate
objects
in
a
manner
not
achievable
traditional
robotics.
While
it
is
possible
to
design
SA
whose
actuation
triggered
via
an
external
stimulus,
the
use
of
single
stimulus
creates
challenges
spatial
and
temporal
control
actuation.
Herein,
4D
printed
multimaterial
soft
actuator
(MMSA)
only
initiated
by
combination
triggers
(i.e.,
pH
temperature)
presented.
Using
3D
printing,
multilayered
hydrophilic
pH-sensitive
layer,
hydrophobic
magnetic
temperature-responsive
shape-memory
polymer
designed.
The
hydrogel
responds
environmental
conditions
swelling
or
shrinking,
while
resist
shape
deformation
until
temperature
light.
these
stimuli-responsive
layers
allows
for
high
level
spatiotemporal
utility
MMSA
demonstrated
series
cargo
capture
release
experiments,
validating
its
ability
demonstrate
active
control.
concept
provides
promising
research
direction
develop
multifunctional
potential
applications
biomedical
engineering
engineering.
Advanced Materials,
Год журнала:
2024,
Номер
36(29)
Опубликована: Май 16, 2024
Bio-inspired
magnetic-responsive
hydrogel
is
confined
in
exceedingly
narrow
spaces
for
soft
robots
and
biomedicine
either
gel
state
or
magnetofluidic
sol
state.
However,
the
motion
of
magnetic
will
be
inhibited
various
irregular
due
to
fixed
shape
size
sol-state
magnetofluid
may
bring
unpredictable
residues
space.
Inspired
by
dynamic
liquid
lubricating
mechanism
biological
systems,
novel
semi-convertible
(MSCH)
developed
through
imbedding
gelatin
amino-modified
Fe
Advanced Materials,
Год журнала:
2024,
Номер
36(23)
Опубликована: Фев. 21, 2024
Medical
microrobotics
is
an
emerging
field
to
revolutionize
clinical
applications
in
diagnostics
and
therapeutics
of
various
diseases.
On
the
other
hand,
mobile
has
important
obstacles
pass
before
translation.
This
article
focuses
on
these
challenges
provides
a
roadmap
medical
microrobots
enable
their
use.
From
concept
"magic
bullet"
physicochemical
interactions
complex
biological
environments
applications,
there
are
several
translational
steps
consider.
Clinical
translation
only
possible
with
close
collaboration
between
experts
researchers
address
technical
microfabrication,
safety,
imaging.
The
application
potential
can
be
materialized
by
designing
that
solve
current
main
challenges,
such
as
actuation
limitations,
material
stability,
imaging
constraints.
strengths
weaknesses
progress
discussed
for
near
future
outlined.
Bioactive Materials,
Год журнала:
2024,
Номер
39, С. 163 - 190
Опубликована: Май 21, 2024
Oral
administration
is
the
most
simple,
noninvasive,
convenient
treatment.
With
increasing
demands
on
targeted
drug
delivery,
traditional
oral
treatment
now
facing
some
challenges:
1)
biologics
how
to
implement
and
ensure
bioavailability
not
lower
than
subcutaneous
injections;
2)
How
achieve
therapy
of
drugs
in
gastrointestinal
tract?
Based
these
two
issues,
delivery
microrobots
have
shown
great
application
prospect
due
their
characteristics
flexible
locomotion
or
driven
ability.
Therefore,
this
paper
summarizes
various
developed
recent
years
divides
them
into
four
categories
according
different
driving
modes:
magnetic-controlled
microrobots,
anchored
self-propelled
biohybrid
microrobots.
As
involve
disciplines
such
as
materials
science,
mechanical
engineering,
medicine,
control
systems,
begins
by
introducing
barriers
that
must
overcome.
Subsequently,
it
provides
an
overview
typical
involved
design
process
To
enhance
readers'
understanding
working
principles
we
present
a
guideline
for
designing
Furthermore,
current
development
status
types
reviewed,
summarizing
respective
advantages
limitations.
Finally,
considering
significant
concerns
regarding
safety
clinical
translation,
discuss
challenges
prospections
translation
presented
paper,
providing
corresponding
suggestions
addressing
existing
challenges.
Advanced Materials,
Год журнала:
2024,
Номер
36(24)
Опубликована: Март 11, 2024
Abstract
Multimodal
and
controllable
locomotion
in
complex
terrain
is
of
great
importance
for
practical
applications
insect‐scale
robots.
Robust
plays
a
particularly
critical
role.
In
this
study,
mechanism
magnetic
robots
based
on
asymmetrical
friction
effect
induced
by
torque
revealed
defined.
The
defined
overcomes
the
design
constraints
imposed
both
robot
substrate
structures,
enabling
realization
multimodal
terrains.
Drawing
inspiration
from
human
walking
running
locomotion,
biped
proposed,
which
not
only
exhibits
rapid
across
substrates
with
varying
coefficients
but
also
achieves
precise
along
patterned
trajectories
through
programmed
controlling.
Furthermore,
apart
its
exceptional
locomotive
capabilities,
demonstrates
remarkable
robustness
terms
load‐carrying
weight‐bearing
performance.
presented
herein
introduce
novel
concept
designing
while
offering
extensive
possibilities
robotics.
International Journal of Extreme Manufacturing,
Год журнала:
2024,
Номер
7(2), С. 022002 - 022002
Опубликована: Ноя. 14, 2024
Highlights
Exploring
personalized
biomedical
metal
implants
through
additive
manufacturing
(AM).
Presenting
new
load-bearing
and
biodegradable
alloys
for
implants.
Showcasing
AI
4D
printing
advancements
in
material
properties.
AM’s
roles
various
medical
fields.
Highlighting
perspectives
of
implant
technology
improved
patient
care.
Cancer
poses
a
substantial
threat
and
serious
challenge
to
public
human
health,
driving
the
promotion
of
sophisticated
technologies
for
cancer
therapy.
While
conventional
chemotherapy
has
bottlenecks
such
as
low
delivery
efficiency,
strong
toxic
side
effects,
tumor
enrichment
barriers,
magnetic
micro/nanorobots
(MNRs)
emerge
promising
therapeutic
candidates
that
provide
alternative
strategies
MNR
is
kind
human-made
machine
micro-
or
nanosized,
reasonably
designed,
performs
command
tasks
through
self-actuated
externally
controlled
propulsion
mechanisms,
which
can
be
potentially
applied
in
theranostics.
Here,
this
review
first
introduces
components
constitute
typical
MNR,
including
body
part,
control
function
sensing
part.
Subsequently,
elucidates
representative
fabrication
methods
construct
MNRs
from
top-down
approaches
bottom-up
approaches,
covering
injection
molding,
self-rolling,
melt
electrospinning
writing,
deposition,
biotemplate
method,
lithography,
assembling,
3D
printing,
chemical
synthesis.
Furthermore,
focuses
on
multiple
applications
facing
diagnosis
treatment,
encompassing
imaging,
quantification,
drug
release,
synergy
with
therapies,
cell
manipulation,
surgical
assistance.
Then,
systematically
elaborates
biocompatibility
biosafety
MNRs.
Finally,
challenges
faced
by
are
discussed
alongside
future
research
directions.
This
intended
scientific
guidance
may
improve
comprehension
cognition
theranostics
platform
MNRs,
promoting
prospering
practical
application
development
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 18, 2025
Abstract
Magnetic
interfacial
microrobots
are
increasingly
recognized
as
a
promising
approach
for
potential
biomedical
applications
ranging
from
electronic
functionalization
to
minimally
invasive
surgery
and
targeted
drug
delivery.
Nevertheless,
existing
research
faces
challenges,
including
less
cooperative
interactions,
contact‐based
cargo
manipulation,
slow
transport
velocity.
Here,
the
magnetic
microrobot
couple
(CMIMC)
is
proposed
address
above
challenges.
The
CMIMC
can
be
maneuvered
by
single
magnet
readily
switched
between
capture
release
states.
By
leveraging
interactions
meticulous
engineering
of
capillary
forces
through
shape
design
surface
treatment,
demonstrates
ability
perform
non‐contact
manipulation.
Using
synergy
preferred
magnetization
directions
field
distribution,
along
with
optimization
resistance‐reducing
shape,
significantly
enhances
velocity,
reaching
12.2
body
length
per
second.
studies
demonstrate
various
like
delivery
myomectomy,
paving
way
broad
implementation
in
fields.
Intrabronchial
delivery
of
therapeutic
agents
is
critical
to
the
treatment
respiratory
diseases.
Targeted
demanded
because
off-target
accumulation
drugs
in
normal
lung
tissues
caused
by
inhalation
and
limited
motion
dexterity
clinical
bronchoscopes
tortuous
bronchial
trees.
Herein,
we
developed
microrobotic
swarms
consisting
magnetic
hydrogel
microparticles
achieve
intrabronchial
targeted
delivery.
Under
programmed
fields,
microgel
particle
performed
controllable
locomotion
adaptative
structure
reconfiguration
air-filled
environments.
The
were
further
integrated
with
imaging
contrast
for
precise
tracking
under
x-ray
fluoroscopy
computed
tomography
imaging.
Magnetic
navigation
an
ex
vivo
phantom
into
deep
branches
trees
achieved.
on-demand
avoiding
particles
from
entering
nontarget
bronchi
tilted
through
climbing
validated.
