Single-Electrode Electrostatic Repulsion Phenomenon for Remote Actuation and Manipulation DOI Creative Commons
Wei Tang, Dong Yan, Kecheng Qin

et al.

Research, Journal Year: 2024, Volume and Issue: 7

Published: Jan. 1, 2024

One of the fundamental principles electrostatics is that an uncharged object will be attracted to a charged through electrostatic induction as two approaches one another. We refer single electrode and examine scenario where positive voltage applied. Because phenomenon, single-electrode only generates attraction forces. Here, we discover can generate repulsion forces define this new phenomenon phenomenon. investigate phenomena, giving curve force versus then defining 3 regions. Remote actuation manipulation are essential technologies enormous concern, with tweezers playing important role. Various designed on basis external fields optics, acoustics, magnetism used for remote manipulation, but some inherent drawbacks still exist. Tweezers would benefit greatly from our discovery in electrostatics. On discovery, propose concept tweezers, which achieve noncontact manipulation. Experimental characterizations successful applications metamaterials, robots, manipulating objects demonstrated produce large deformation rates (>6,000%), fast (>100 Hz), distance (~15 cm) have advantages simple device structure, easy control, lightweight, no dielectric breakdown, low cost. Our work may deepen people’s understanding opens opportunities

Language: Английский

4D Multimaterial Printing of Soft Actuators with Spatial and Temporal Control DOI Creative Commons
Kun Zhou, Rujie Sun, Jonathan P. Wojciechowski

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(19)

Published: Jan. 30, 2024

Soft actuators (SAs) are devices which can interact with delicate objects in a manner not achievable traditional robotics. While it is possible to design SA whose actuation triggered via an external stimulus, the use of single stimulus creates challenges spatial and temporal control actuation. Herein, 4D printed multimaterial soft actuator (MMSA) only initiated by combination triggers (i.e., pH temperature) presented. Using 3D printing, multilayered hydrophilic pH-sensitive layer, hydrophobic magnetic temperature-responsive shape-memory polymer designed. The hydrogel responds environmental conditions swelling or shrinking, while resist shape deformation until temperature light. these stimuli-responsive layers allows for high level spatiotemporal utility MMSA demonstrated series cargo capture release experiments, validating its ability demonstrate active control. concept provides promising research direction develop multifunctional potential applications biomedical engineering engineering.

Language: Английский

Citations

15

Bio‐Inspired Magnetic‐Responsive Supramolecular‐Covalent Semi‐Convertible Hydrogel DOI
Feng Gao,

Hongyue Jiang,

Dayang Wang

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(29)

Published: May 16, 2024

Bio-inspired magnetic-responsive hydrogel is confined in exceedingly narrow spaces for soft robots and biomedicine either gel state or magnetofluidic sol state. However, the motion of magnetic will be inhibited various irregular due to fixed shape size sol-state magnetofluid may bring unpredictable residues space. Inspired by dynamic liquid lubricating mechanism biological systems, novel semi-convertible (MSCH) developed through imbedding gelatin amino-modified Fe

Language: Английский

Citations

15

Roadmap for Clinical Translation of Mobile Microrobotics DOI Creative Commons
Ugur Bozuyuk, Paul Wrede, Erdost Yıldız

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(23)

Published: Feb. 21, 2024

Medical microrobotics is an emerging field to revolutionize clinical applications in diagnostics and therapeutics of various diseases. On the other hand, mobile has important obstacles pass before translation. This article focuses on these challenges provides a roadmap medical microrobots enable their use. From concept "magic bullet" physicochemical interactions complex biological environments applications, there are several translational steps consider. Clinical translation only possible with close collaboration between experts researchers address technical microfabrication, safety, imaging. The application potential can be materialized by designing that solve current main challenges, such as actuation limitations, material stability, imaging constraints. strengths weaknesses progress discussed for near future outlined.

Language: Английский

Citations

12

Oral administration microrobots for drug delivery DOI Creative Commons

An Ren,

Jiarui Hu, Changwei Qin

et al.

Bioactive Materials, Journal Year: 2024, Volume and Issue: 39, P. 163 - 190

Published: May 21, 2024

Oral administration is the most simple, noninvasive, convenient treatment. With increasing demands on targeted drug delivery, traditional oral treatment now facing some challenges: 1) biologics how to implement and ensure bioavailability not lower than subcutaneous injections; 2) How achieve therapy of drugs in gastrointestinal tract? Based these two issues, delivery microrobots have shown great application prospect due their characteristics flexible locomotion or driven ability. Therefore, this paper summarizes various developed recent years divides them into four categories according different driving modes: magnetic-controlled microrobots, anchored self-propelled biohybrid microrobots. As involve disciplines such as materials science, mechanical engineering, medicine, control systems, begins by introducing barriers that must overcome. Subsequently, it provides an overview typical involved design process To enhance readers' understanding working principles we present a guideline for designing Furthermore, current development status types reviewed, summarizing respective advantages limitations. Finally, considering significant concerns regarding safety clinical translation, discuss challenges prospections translation presented paper, providing corresponding suggestions addressing existing challenges.

Language: Английский

Citations

12

Insect‐Scale Biped Robots Based on Asymmetrical Friction Effect Induced by Magnetic Torque DOI Creative Commons
Jinsheng Zhao, Xin Chen, Jiaqi Zhu

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(24)

Published: March 11, 2024

Abstract Multimodal and controllable locomotion in complex terrain is of great importance for practical applications insect‐scale robots. Robust plays a particularly critical role. In this study, mechanism magnetic robots based on asymmetrical friction effect induced by torque revealed defined. The defined overcomes the design constraints imposed both robot substrate structures, enabling realization multimodal terrains. Drawing inspiration from human walking running locomotion, biped proposed, which not only exhibits rapid across substrates with varying coefficients but also achieves precise along patterned trajectories through programmed controlling. Furthermore, apart its exceptional locomotive capabilities, demonstrates remarkable robustness terms load‐carrying weight‐bearing performance. presented herein introduce novel concept designing while offering extensive possibilities robotics.

Language: Английский

Citations

9

Magnetic Micro/nanorobots in Cancer Theranostics: From Designed Fabrication to Diverse Applications DOI
Lin Zhang, Shuren Wang, Yanglong Hou

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 19, 2025

Cancer poses a substantial threat and serious challenge to public human health, driving the promotion of sophisticated technologies for cancer therapy. While conventional chemotherapy has bottlenecks such as low delivery efficiency, strong toxic side effects, tumor enrichment barriers, magnetic micro/nanorobots (MNRs) emerge promising therapeutic candidates that provide alternative strategies MNR is kind human-made machine micro- or nanosized, reasonably designed, performs command tasks through self-actuated externally controlled propulsion mechanisms, which can be potentially applied in theranostics. Here, this review first introduces components constitute typical MNR, including body part, control function sensing part. Subsequently, elucidates representative fabrication methods construct MNRs from top-down approaches bottom-up approaches, covering injection molding, self-rolling, melt electrospinning writing, deposition, biotemplate method, lithography, assembling, 3D printing, chemical synthesis. Furthermore, focuses on multiple applications facing diagnosis treatment, encompassing imaging, quantification, drug release, synergy with therapies, cell manipulation, surgical assistance. Then, systematically elaborates biocompatibility biosafety MNRs. Finally, challenges faced by are discussed alongside future research directions. This intended scientific guidance may improve comprehension cognition theranostics platform MNRs, promoting prospering practical application development

Language: Английский

Citations

1

Octopus-crawling-inspired highly agile miniature piezoelectric robot with strong load-bearing capacity DOI
Binbin Zhu, Yan Qing Wang

International Journal of Mechanical Sciences, Journal Year: 2025, Volume and Issue: unknown, P. 110130 - 110130

Published: March 1, 2025

Language: Английский

Citations

1

Bio‐Integrated Microrobots: Fabrication, Actuation and Biomedical Applications DOI Creative Commons
Huaping Wang, Jiaxin Liu, Ru‐xin Nie

et al.

Published: March 13, 2025

ABSTRACT Bio‐integrated microrobots (BIMs), which are fabricated with biofriendly materials, biological units (e.g. cells or biomolecules), cell‐material hybrids have emerged as a promising technology for minimally invasive biomedicine. The diminutive size and flexible structures enable BIMs to navigate within narrow, deep, challenging‐to‐reach in vivo regions, performing biopsy, diagnostic, drug delivery, therapeutic functions minimal invasiveness. However, the clinical deployment of is highly orchestrated task that requires consideration material properties, structural design, locomotion, observation, outcomes, side effects on tissues, etc. In this review, we review discuss latest advances bio‐integrated microrobot domain, evaluating various methods associated fabrication, actuation, implementation biomedical BIMs. By comparing advantages shortcomings these techniques, highlights challenges future trends intelligent microrobots, huge potential

Language: Английский

Citations

1

Revolutionizing Medical Implant Fabrication: Advances in Additive Manufacturing of Biomedical Metals DOI Creative Commons
Yu-Hua Li, Deyu Jiang, Rui Zhu

et al.

International Journal of Extreme Manufacturing, Journal Year: 2024, Volume and Issue: 7(2), P. 022002 - 022002

Published: Nov. 14, 2024

Highlights Exploring personalized biomedical metal implants through additive manufacturing (AM). Presenting new load-bearing and biodegradable alloys for implants. Showcasing AI 4D printing advancements in material properties. AM’s roles various medical fields. Highlighting perspectives of implant technology improved patient care.

Language: Английский

Citations

8

3D-printed microrobots for biomedical applications DOI

Kun Wei,

Chenlong Tang,

Hui Ma

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(17), P. 4301 - 4334

Published: Jan. 1, 2024

Microrobots, which can perform tasks in difficult-to-reach parts of the human body under their own or external power supply, are potential tools for biomedical applications, such as drug delivery, microsurgery, imaging and monitoring, tissue engineering, sensors actuators. Compared with traditional fabrication methods microrobots, recent improvements 3D printers enable them to print high-precision breaking through limitations micromanufacturing technologies that require high skills operators greatly shortening design-to-production cycle. Here, this review first introduces typical printing used microrobot manufacturing. Then, structures microrobots different functions application scenarios discussed. Next, we summarize materials (body materials, propulsion intelligent materials) manufacturing complete construction realize applications (

Language: Английский

Citations

7