Food Research International, Год журнала: 2025, Номер 201, С. 115677 - 115677
Опубликована: Янв. 5, 2025
Язык: Английский
Microbial Cell Factories, Год журнала: 2021, Номер 20(1)
Опубликована: Ноя. 16, 2021
Abstract Many applications of microbial synthetic biology, such as metabolic engineering and biocomputing, are increasing in design complexity. Implementing complex tasks single populations can be a challenge because large genetic circuits burdensome difficult to optimize. To overcome these limitations, consortia engineered distribute among multiple populations. Recent studies have made substantial progress programming for both basic understanding potential applications. Microbial been designed through diverse strategies, including mutualistic interactions, using programmed population control prevent overgrowth individual populations, spatial segregation reduce competition. Here, we highlight the role advances engineering, biofilm production living materials, biosensing. Additionally, discuss challenges future research consortia.
Язык: Английский
Процитировано
81
Current Opinion in Biotechnology, Год журнала: 2021, Номер 67, С. 72 - 79
Опубликована: Янв. 28, 2021
In nature, microorganisms live in multi-species communities allowing microbial interactions. These interactions are lost upon establishing a pure culture, increasing the metabolic burden and limiting potential of isolated microbe. past years, synthetic co-cultivation, using well-defined consortia two or more microbes, was increasingly explored for innovative applications biotechnology. As such, interspecies take place without complexity an open mixed minimizing undesired side reactions. Ultimately, co-cultivation allows to well-characterized microbes 'off-the-shelf' create ecosystems with improved process capabilities. This review highlights some recent developments on focusing waste-to-chemicals conversions. It also addresses fundamental knowledge deriving from these studies, which is important further develop our ability engineer functional co-cultures bioproduction.
Язык: Английский
Процитировано
79
Chemical Society Reviews, Год журнала: 2021, Номер 50(22), С. 12576 - 12615
Опубликована: Янв. 1, 2021
This review provides a comprehensive introduction to microorganisms-based biohybrid systems, namely MAMO, for application in tumor therapeutics.
Язык: Английский
Процитировано
71
Molecules, Год журнала: 2021, Номер 26(17), С. 5411 - 5411
Опубликована: Сен. 6, 2021
Lignocellulose is a kind of renewable bioresource containing abundant polysaccharides, which can be used for biochemicals and biofuels production. However, the complex structure hinders final efficiency lignocellulosic biorefinery. This review comprehensively summarizes hydrolases typical microorganisms degradation. Moreover, commonly bioprocesses biorefinery are also discussed, including separated hydrolysis fermentation, simultaneous saccharification fermentation consolidated bioprocessing. Among these methods, construction microbial co-culturing systems via bioprocessing regarded as potential strategy to efficiently produce biofuels, providing theoretical direction constructing efficient stable process system in future.
Язык: Английский
Процитировано
68
Energy & Environmental Science, Год журнала: 2022, Номер 15(6), С. 2529 - 2536
Опубликована: Янв. 1, 2022
A photosynthesis-driven biophotovoltaic system with an Al-anode powered a microprocessor widely used in IoT applications stably for over six months.
Язык: Английский
Процитировано
60
Microorganisms, Год журнала: 2021, Номер 10(1), С. 39 - 39
Опубликована: Дек. 26, 2021
Polyethylene terephthalate (PET) is a widely used plastic that polymerized by terephthalic acid (TPA) and ethylene glycol (EG). In recent years, PET biodegradation bioconversion have become important in solving environmental pollution. More more hydrolases been discovered modified, which mainly act on degrade the ester bond of PET. The monomers, TPA EG, can be further utilized microorganisms, entering tricarboxylic cycle (TCA cycle) or being converted into high value chemicals, finally realizing Based synthetic biology metabolic engineering strategies, this review summarizes current advances modified hydrolases, engineered microbial chassis degrading PET, pathways artificial consortia bioconversion. Artificial consortium provides novel ideas for other complex polymers. It helpful to realize one-step chemicals.
Язык: Английский
Процитировано
58
Current Opinion in Biotechnology, Год журнала: 2022, Номер 75, С. 102706 - 102706
Опубликована: Март 4, 2022
In natural ecosystems, microorganisms live in communities where each member interacts with the others and environment to efficiently utilise available resources. Division of Labor (DOL) is an evolutionary strategy that evolved by microbial accomplish complex tasks. Current bio-based technologies could also benefit from DOL construct robust cell factories expanded metabolic capabilities. Here, we review some remarkable examples how used consortia utilize a range substrates. Also, most recent studies towards engineering design synthetic for efficient substrate utilization bioproduction.
Язык: Английский
Процитировано
48
Bioresource Technology, Год журнала: 2022, Номер 352, С. 127083 - 127083
Опубликована: Март 30, 2022
Язык: Английский
Процитировано
47
Microorganisms, Год журнала: 2022, Номер 10(8), С. 1537 - 1537
Опубликована: Июль 29, 2022
Polyolefins, including polyethylene (PE), polypropylene (PP) and polystyrene (PS), are widely used plastics in our daily life. The excessive use of improper handling methods cause considerable pollution the environment, as well waste energy. biodegradation polyolefins seems to be an environmentally friendly low-energy consumption method for degradation. Many strains that could degrade have been isolated from environment. Some enzymes also identified with function polyolefin With development synthetic biology metabolic engineering strategies, engineered plastics. This review summarizes current advances degradation, strains, related pathways. Furthermore, a novel strategy degradation by artificial microbial consortia is proposed, which would helpful efficient polyolefin.
Язык: Английский
Процитировано
43
Trends in biotechnology, Год журнала: 2023, Номер 41(11), С. 1430 - 1441
Опубликована: Июнь 16, 2023
Язык: Английский
Процитировано
27