Influence of mesh selectivity on risk assessment of marine microplastics

Marine Pollution Bulletin, Год журнала: 2025, Номер 212, С. 117538 - 117538

Опубликована: Янв. 9, 2025

Язык: Английский

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Polylactic Acid Micro/Nanoplastic Exposure Induces Male Reproductive Toxicity by Disrupting Spermatogenesis and Mitochondrial Dysfunction in Mice

ACS Nano, Год журнала: 2025, Номер unknown

Опубликована: Янв. 27, 2025

Although considered an "eco-friendly" biodegradable plastic, polylactic acid (PLA) microplastic (PLA-MP) poses a growing concern for human health, yet its effects on male reproductive function remain underexplored. This study investigated the toxicity of PLA in mice and potential mechanisms. To this end, our vivo vitro experiments demonstrated that after degradation digestive system, significant number PLA-MP-derived nanoparticles could penetrate blood–testis barrier (BTB) localize within spermatogenic microenvironment. Mice exposed to PLA-MPs long time exhibited toxicity, evidenced by decreased sperm concentration motility, increased deformity rates, disrupted sex hormone levels. Further analysis revealed impaired BTB, induced mitochondrial dysfunction testes, triggered oxidative stress through excessive ROS production from mitochondria, leading further testicular damage. Notably, nanoplastics internalized sheath structure sperm, causing dose-dependent impairments function. Transcriptome analyses indicated spermatogenesis inhibiting expression key mRNA involved process. Collectively, findings highlight toxic effect damaging BTB impairing function, which provides insights into toxicological implications microplastics mammalian fertility.

Язык: Английский

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A screening method for polyester films-degrading microorganisms and enzymes

Journal of Hazardous Materials, Год журнала: 2025, Номер 487, С. 137177 - 137177

Опубликована: Янв. 10, 2025

Enzymatic degradation of plastic pollution offers a promising environmentally friendly waste management strategy, however, suitable biocatalysts must be screened and developed. Traditional screening methods using soluble or solubilised polymers do not necessarily identify enzymes that are effective against solid crystalline polymers. This study presents simple, time-saving cost-effective method for identifying microorganisms capable degrading polymeric films. The was tested on polycaprolactone (PCL), polyethylene terephthalate (PET), polylactate (PLA) polyhydroxybutyrate/polyhydroxyvalerate (PHB/PHV) It involves two steps: first, PCL diol (PCLD)-degrading agar plates, second, testing these polyester Using this method, over 100 PCLD-degrading 27 E. coli clones carrying genomic metagenomic DNA fragments have been isolated. In addition, recombinant cutinases from Streptomyces scabiei Thermobifida fusca tested. Approximately 66 % the forming halos PCLD plates hydrolysed 6 - biaxially oriented PET film. five PLA- four PHB/PHV-degrading esterases identified. proposed is detecting both wild-type microorganisms, as well in vitro transcription-translation reactions. Screening thermostable thermophilic enzymes, including those resistant to organic solvents environmental inhibitors, also easily implemented.

Язык: Английский

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Microplastics enhance the prevalence of antibiotic resistance genes in mariculture sediments by enriching host bacteria and promoting horizontal gene transfer

Eco-Environment & Health, Год журнала: 2025, Номер unknown, С. 100136 - 100136

Опубликована: Янв. 1, 2025

Microplastics (MPs) and antibiotic resistance genes (ARGs) pose significant challenges to the One Health framework due their intricate multifaceted ecological environmental impacts. However, understanding of how MP properties influence ARG prevalence in mariculture sediments remains limited. Herein, polystyrene (PS) polyvinyl chloride (PVC) MPs with different sizes (20-120 μm 0.5-2.0 mm) were selected evaluate impacts underlying mechanisms driving ARGs dissemination. The results showed that PS PVC increased relative abundance by 1.41-2.50-fold 2.01-2.84-fold, respectively, compared control, particularly high-risk genes. polymer type effect was identified as more influential than size sediment resistome evolution. shifted microbial community assembly from stochastic deterministic processes, thus enriching host pathogens. Furthermore, highly hydrophobic not only recruited bacteria colonization but also facilitated exchange within plastisphere. exogenous additives released (e.g., heavy metals, bisphenol A, tridecyl ester) particles synergistically promoted conjugative transfer inducing oxidative stress enhancing cell membrane permeability. These findings revealed characteristics spread marine benthic ecosystems, underscoring importance mitigating pollution maintain ecosystem health, prevent zoonotic diseases, balance global health.

Язык: Английский

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Aggregation behavior of photoaging nanoplastics in artificial sweat solutions

Journal of Hazardous Materials, Год журнала: 2025, Номер 488, С. 137466 - 137466

Опубликована: Фев. 1, 2025

Язык: Английский

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Insights into effects of drying–wetting cycles on dissolved organic matter and Cd bioavailability in riparian sediments amended with microplastics.

Environmental Research, Год журнала: 2025, Номер unknown, С. 121087 - 121087

Опубликована: Фев. 1, 2025

Язык: Английский

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Identification of Microplastics in Human Tear Fluid and Meibum: Implications for Dry Eye Disease Pathogenesis

Journal of Hazardous Materials, Год журнала: 2025, Номер 489, С. 137635 - 137635

Опубликована: Фев. 18, 2025

Язык: Английский

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Enhanced ecological risk of microplastic ingestion by fish due to fragmentation and deposition in heavily sediment-laden river

Water Research, Год журнала: 2025, Номер 278, С. 123306 - 123306

Опубликована: Фев. 20, 2025

Язык: Английский

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Human microplastic removal: what does the evidence tell us?

Brain medicine :, Год журнала: 2025, Номер unknown, С. 1 - 2

Опубликована: Март 4, 2025

The increased levels of microplastics and nanoplastics (MNPs) found in human brain tissue are alarming, particularly patients with dementia. Although total avoidance MNP exposure will likely remain an unattainable endpoint light their ubiquity the environment, new studies indicate feasible pathways by which dietary intake may be decreased or clearances improved. This commentary reviews evidence on to MNPs, penetration, potential health effects, neurotoxicity. We explore evidence-based strategies for reducing through lifestyle changes while addressing key gaps our current knowledge calling additional research.

Язык: Английский

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Mechanistic applications of low-temperature plasma in starch-based biopolymer film: A review

Food Chemistry, Год журнала: 2025, Номер 479, С. 143739 - 143739

Опубликована: Март 5, 2025

Язык: Английский

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