Human Microbiome Journal,
Год журнала:
2018,
Номер
7-8, С. 1 - 9
Опубликована: Фев. 23, 2018
The
gut
microbiota
is
an
ecosystem
including
all
bacterial
species
that
permanently
colonize
the
gastro
intestinal
tract
and
a
large
number
of
other
microorganisms
from
environment.
These
millions
may
be
unbalanced
by
external
internal
factors.
aim
this
review
to
summarize
recent
findings
on
animal
human
studies
effect
dietary
geographical
provenance
microbiota-composition.
It
includes
results
influence
products,
type
diet
(e.g.
vegetarian
omnivorous
subgroups),
geographic
areas,
as
well
differences
between
populations
within
same
area.
In
models,
most
showed
contradictory
effects
modulation
phylum,
while
in
studies,
such
fat,
are
often
reported
being
associated
with
increase
Bacteroidetes
Actinobacteria
decrease
those
Firmicutes
Proteobacteria
phylum.
different
group
has
higher
diversity
bacteria
compared
vegetarians.
Gut
composition
differs
widely
areas
ethnic
groups
However,
was
encountered
African
population.
conclusions
highlight
according
eating
habits
which
closely
correlated
location
suggesting
therefore,
need
for
more
in-depth
research,
looking
at
habits.
World Journal of Gastroenterology,
Год журнала:
2015,
Номер
21(29), С. 8787 - 8787
Опубликована: Янв. 1, 2015
Relation
between
the
gut
microbiota
and
human
health
is
being
increasingly
recognised.It
now
well
established
that
a
healthy
flora
largely
responsible
for
overall
of
host.The
normal
comprises
two
major
phyla,
namely
Bacteroidetes
Firmicutes.Though
in
an
infant
appears
haphazard,
it
starts
resembling
adult
by
age
3
years.Nevertheless,
there
exist
temporal
spatial
variations
microbial
distribution
from
esophagus
to
rectum
all
along
individual's
life
span.Developments
genome
sequencing
technologies
bioinformatics
have
enabled
scientists
study
these
microorganisms
their
function
microbehost
interactions
elaborate
manner
both
disease.The
imparts
specific
host
nutrient
metabolism,
xenobiotic
drug
maintenance
structural
integrity
mucosal
barrier,
immunomodulation,
protection
against
pathogens.Several
factors
play
role
shaping
microbiota.They
include
(1)
mode
delivery
(vaginal
or
caesarean);
(2)
diet
during
infancy
(breast
milk
formula
feeds)
adulthood
(vegan
based
meat
based);
(3)
use
antibiotics
antibiotic
like
molecules
are
derived
environment
commensal
community.A
concern
long-term
alteration
horizontal
transfer
resistance
genes
could
result
reservoir
organisms
with
multidrug
resistant
gene
pool.
Nature Microbiology,
Год журнала:
2016,
Номер
1(12)
Опубликована: Ноя. 7, 2016
Abstract
Metagenomics
revolutionized
the
understanding
of
relations
among
human
microbiome,
health
and
diseases,
but
generated
a
countless
number
sequences
that
have
not
been
assigned
to
known
microorganism
1
.
The
pure
culture
prokaryotes,
neglected
in
recent
decades,
remains
essential
elucidating
role
these
organisms
2
We
recently
introduced
microbial
culturomics,
culturing
approach
uses
multiple
conditions
matrix-assisted
laser
desorption/ionization–time
flight
16S
rRNA
for
identification
Here,
we
selected
best
increase
studied
samples
applied
new
protocols
(fresh-sample
inoculation;
detection
microcolonies
specific
cultures
Proteobacteria
microaerophilic
halophilic
prokaryotes)
address
weaknesses
previous
studies
3–5
identified
1,057
prokaryotic
species,
thereby
adding
531
species
gut
repertoire:
146
bacteria
humans
gut,
187
archaea
previously
isolated
humans,
197
potentially
species.
Genome
sequencing
was
performed
on
By
comparing
results
metagenomic
culturomic
analyses,
show
use
culturomics
allows
corresponding
assigned.
Altogether,
doubles
at
least
once
from
gut.
Microbial Biotechnology,
Год журнала:
2019,
Номер
12(6), С. 1109 - 1125
Опубликована: Апрель 21, 2019
Summary
Akkermansia
muciniphila
(
A.
),
an
intestinal
symbiont
colonizing
in
the
mucosal
layer,
is
considered
to
be
a
promising
candidate
as
probiotics.
known
have
important
value
improving
host
metabolic
functions
and
immune
responses.
Moreover,
may
modifying
cancer
treatment.
However,
most
of
current
researches
focus
on
correlation
between
diseases,
little
about
causal
relationship
them.
Few
intervention
studies
are
limited
animal
experiments,
explored
its
safety
efficacy
humans.
Therefore,
critical
analysis
knowledge
will
play
foundation
for
it
defined
new
beneficial
microbe.
This
article
review
bacteriological
characteristics
,
well
with
disorders,
diseases
therapy.
Frontiers in Microbiology,
Год журнала:
2016,
Номер
7
Опубликована: Авг. 19, 2016
The
intestinal
microbiota
has
increasingly
been
shown
to
have
a
vital
role
in
various
aspects
of
human
health.
Indeed,
several
studies
linked
alterations
the
gut
with
development
different
diseases.
Among
vast
bacterial
community,
Bifidobacterium
is
genus
which
dominates
intestine
healthy
breast-fed
infants
whereas
adulthood
levels
are
lower
but
relatively
stable.
presence
species
bifidobacteria
changes
age,
from
childhood
old
age.
longum,
breve
and
bifidum
generally
dominant
catenulatum,
adolescentis
and,
as
well
B.
longum
more
adults.
Increasingly,
evidence
accumulating
shows
beneficial
effect
supplementation
for
improvement
health
conditions
ranging
protection
against
infection
extra-
intra-intestinal
positive
effects.
Moreover,
can
be
associated
production
number
potentially
promoting
metabolites
including
short
chain
fatty
acids,
conjugated
linoleic
acid
bacteriocins.
aim
this
mini-review
describe
composition
stages
life,
highlighting
their
role,
commonly
known
disease
states.
