Gender Differences in Potentially Inappropriate Medication Use among Older Adults
Pharmaceuticals,
Год журнала:
2023,
Номер
16(6), С. 869 - 869
Опубликована: Июнь 12, 2023
Use
of
potentially
inappropriate
medication
(PIMs)
is
a
prominent
concern
that
leads
to
significant
medication-related
issues
among
older
adults.
Notably,
women
tend
utilize
more
medicines
than
men;
frequently
take
drugs.
In
addition,
some
evidence
suggests
prescription
PIMs
vary
by
gender.
This
study
examines
the
gender-based
variation
in
prescribing
PIM
adults
Saudi
Arabia.A
cross-sectional
retrospective
analysis
electronic
medical
records
from
large
hospital
Arabia
was
carried
out.
Patients
over
age
65
who
received
ambulatory
treatment
were
included
study.
The
utilization
assessed
based
on
Beers
criteria.
Descriptive
statistics
and
logistic
regression
employed
describe
patterns
identify
factors
associated
with
their
use.
All
statistical
analyses
performed
using
Version
9.4
Statistical
Analysis
Software
(SAS®
9.4).The
comprised
4062
people
(age
65)
visited
care
clinics;
average
(72.6
±
6.2)
years.
majority
sample
(56.8%).
Among
adults,
44.7%
men
58.3%
reported
having
should
be
avoided,
indicating
higher
prevalence
compared
men.
terms
categories
used,
had
much
rate
cardiovascular
gastrointestinal
drugs
men,
use
hypertension,
ischemic
heart
disease,
asthma,
osteoarthritis,
cancer,
while
age,
dyslipidemia,
chronic
kidney
osteoporosis.This
revealed
sex
differences
adults;
common
women.
Sex
exist
clinical
socioeconomic
characteristics
related
medications.
essential
areas
could
targeted
further
interventions
improve
drug-prescribing
practices
at
risk
PIM.
Язык: Английский
Patient‐Related Factors Associated With the Initiation of Potentially Inappropriate Medication in Home Care: An Observational Study Based on Resident Assessment Instrument Data
Basic & Clinical Pharmacology & Toxicology,
Год журнала:
2025,
Номер
136(2)
Опубликована: Янв. 8, 2025
ABSTRACT
Background
The
harmful
outcomes
of
potentially
inappropriate
medications
(PIMs)
are
highlighted
among
multimorbid
older
home
care
clients
using
several
medicines.
aim
this
study
was
to
identify
patient‐related
factors
associated
with
the
initiation
PIMs.
Methods
This
register‐based
used
Resident
Assessment
Instrument‐Home
Care
(RAI‐HC)
assessments
(
n
=
6176)
from
year
2014
2015.
PIMs
were
identified
according
Beers
criteria.
Generalised
estimating
equations
Findings
A
total
228
(11.3%)
initiated
during
follow‐up
(mean
13
months).
Factors
higher
odds
initiate
education
(OR
1.36,
95%
CI
1.02–1.82),
cognitive
impairment
1.70,
1.02–2.82),
reduced
social
interaction
1.50,
1.06–2.13),
independent
activity
outdoors
1.72,
1.18–2.51),
diabetes
1.47,
1.12–1.94),
Parkinson's
disease
3.42,
1.86–6.27)
and
longer
interval
between
RAI
1.09
per
month,
1.02–1.18).
Conclusions
Incidence
common.
results
help
healthcare
professionals
focus
more
attention
on
susceptible
PIM
prescribing.
Preventing
use
is
essential,
especially
adults
impairment,
prevent
further
decline
health
status
admission
long‐term
care.
Язык: Английский
Self-reported and accelerometer-based assessment of physical activity in older adults: results from the Berlin Aging Study II
Scientific Reports,
Год журнала:
2023,
Номер
13(1)
Опубликована: Июнь 21, 2023
Abstract
Physical
activity
(PA)
has
a
substantial
impact
on
health
and
mortality.
Besides
questionnaires
that
rely
subjective
assessment
of
levels,
accelerometers
can
help
to
objectify
an
individual’s
PA.
In
this
study,
variables
estimating
PA
sleep
time
obtained
through
the
wGT3X-BT
monitor
(ActiGraph
LLC,
USA)
in
797
participants
Berlin
Aging
Study
II
(BASE-II)
were
analyzed.
Self-reports
recorded
with
Rapid
Assessment
Activity
(RAPA)
Pittsburgh
Sleep
Quality
Index
questionnaire
(PSQI).
Total
cholesterol
(TC),
high
density
lipoprotein
(HDL-C),
low
(LDL-C),
triglycerides
(TG),
fasting
glucose,
hemoglobin
A1c
(HbA1c)
determined
accredited
standard
laboratory.
Of
all
participants,
760
fulfilled
wear-time
criteria.
sample
mean
age
was
75.6
years
(SD:
3.8
years,
range
66.0–94.1
years)
53%
included
women.
Average
wear
23.2
h/day
(SD
1.3
h/day).
Statistically
significant
differences
between
RAPA
groups
found
for
accelerometric
except
energy
expenditure.
Post-hoc
analysis,
however,
suggested
agreement
device-based
physical
activity.
TC,
HDL-C,
LDL-C,
TG,
glucose
HbA1c
weakly
correlated
(Pearson’s
r
≤
0.25).
Device-based
average
per
night
(mean
=
6.91
h,
SD
1.3,
n
720)
self-reported
7.1
1.15
410)
comparable
moderately
0.31,
p
<
0.001,
410).
Results
from
study
suggest
measures
assessed
by
are
partially
inconsistent
terms
level
participants.
Self-reported
night,
comparable.
Язык: Английский
Sex Differences in Multimorbidity, Inappropriate Medication and Adverse Outcomes of Inpatient Care: MoPIM Cohort Study
International Journal of Environmental Research and Public Health,
Год журнала:
2023,
Номер
20(4), С. 3639 - 3639
Опубликована: Фев. 18, 2023
There
is
no
published
evidence
on
the
possible
differences
in
multimorbidity,
inappropriate
prescribing,
and
adverse
outcomes
of
care,
simultaneously,
from
a
sex
perspective
older
patients.
We
aimed
to
identify
those
patients
hospitalized
because
chronic
disease
exacerbation.
A
multicenter,
prospective
cohort
study
740
(≥65
years)
was
designed,
registering
sociodemographic
variables,
frailty,
Barthel
index,
conditions
(CCs),
geriatric
syndromes
(GSs),
polypharmacy,
potentially
prescribing
(PIP)
according
STOPP/START
criteria,
drug
reactions
(ADRs).
Outcomes
were
length
stay
(LOS),
discharge
nursing
home,
in-hospital
mortality,
cause
existence
any
ADR
its
worst
consequence.
Bivariate
analyses
between
all
variables
performed,
network
graph
created
for
each
using
CC
GS.
total
included
(53.2%
females,
53.5%
≥85
years
old).
Women
presented
higher
prevalence
more
living
home
or
alone,
had
percentage
PIP
related
anxiolytics
pain
management
drugs.
Moreover,
they
significant
pairwise
associations
CC,
such
as
asthma,
vertigo,
thyroid
diseases,
osteoarticular
sleep
disorders,
with
GS,
pain,
constipation,
anxiety/depression.
No
immediate
care
observed
men
women
exacerbation
episode.
Язык: Английский
Oordeelkundig medicatiebeleid bij ouderen: aandacht voor geslachts- en genderaspecten
Tijdschrift voor Geneeskunde,
Год журнала:
2023,
Номер
unknown
Опубликована: Июль 24, 2023
Judicious
medication
use
in
older
people:
pay
attention
to
sex
and
gender
aspects
Polypharmacy
is
prevalent
among
adults
the
risk
of
inappropriate
prescribing
increases
with
age.
Older
adults,
particularly
women,
are
at
high
for
medication-related
problems.
This
review
article
focuses
on
optimizing
proposes
a
practical
approach
evaluating
managing
daily
practice
describes
how
can
play
role
appropriate
prescribing.
Язык: Английский