International Urology and Nephrology, Год журнала: 2024, Номер 56(11), С. 3519 - 3527
Опубликована: Июнь 22, 2024
Язык: Английский
Journal of Affective Disorders, Год журнала: 2024, Номер 351, С. 31 - 39
Опубликована: Янв. 26, 2024
Язык: Английский
Процитировано
18
BMC Oral Health, Год журнала: 2024, Номер 24(1)
Опубликована: Янв. 4, 2024
Abstract Background The American Heart Association has developed a novel cardiovascular health indicator called Life’s Essential 8 (LE8). However, no one reported using LE8 to assess periodontitis. This study aimed investigate the association between and periodontitis in adults. Methods Data from National Health Nutrition Examination Survey (NHANES) 2009 2014 were used for this investigation. was independent variable, it is divided into three grades: high, moderate, low. Periodontitis dependent classification of based on criteria Eke 2012. Multivariable logistic regression models explore relationship Results A total 9,039 participants with an average age 52.16 ± 14.21 years enrolled study, whom 48.29% male 51.71% female. mean standard deviation 66.29 14.57, prevalence 50.48% overall. score fully adjusted model showed negative correlation (OR = 0.98; 95% CI, 0.98–0.99, p < 0.001). result persisted when categorized low, high groups. Compared those lowest group, highest group had 47% decreased risk 0.53; 0.46–0.66, P Conclusions cross-sectional investigation revealed likelihood
Язык: Английский
Процитировано
13
Archives of Dermatological Research, Год журнала: 2025, Номер 317(1)
Опубликована: Фев. 22, 2025
Язык: Английский
Процитировано
1
Scientific Reports, Год журнала: 2024, Номер 14(1)
Опубликована: Окт. 14, 2024
It is currently unclear whether there a connection between Life's Essential 8 (LE8) and cardiovascular disease (CVD), as well mortality in people with nonalcoholic fatty liver (NAFLD). Our goal was to explore these relationships by examining data collected the National Health Nutrition Examination Survey (NHANES) from 2005 2018. We identified eligible participants NAFLD based on NHANES 2005-2018 data. CVD status acquired through self-reported information, using Death Index, were prospectively matched. The diagnosis of relied noninvasive biomarkers. research involved 9094 individuals who having NAFLD, mean age 52.05 years. Each incremental LE8 score exhibited significant association, leading 3%, 4%, 4% reduction odds experiencing CVD, ischemic heart disease, congestive failure, coronary attack, angina, stroke NAFLD. A strong correlation found maintaining superior level Cardiovascular (CVH), shown ranging 80 100, reduced occurrence its various forms (all p for trend < 0.0001). Likewise, demonstrated protective benefits showing that following high CVH (in contrast low CVH) linked reductions 64%, 71%, 74% all-cause, cancer mortality, respectively. Restricted cubic spline analyses suggested noteworthy dose-response specifically types nonlinear mortality. Interaction highlighted race effect modifiers. CVH, evaluated LE8, an independent association decreased risk findings substantiate adhering may alleviate excessive burden context
Язык: Английский
Процитировано
5
European Journal of Preventive Cardiology, Год журнала: 2025, Номер unknown
Опубликована: Янв. 31, 2025
To assess whether better cardiovascular health is associated with a lower long-term risk of CVD in women history adverse pregnancy outcomes (APOs). Using data from the UK Biobank prospective cohort, we included 2,263 participants prior APOs and 107,260 without APOs. Life's Essential 8 (LE8) score was assessed at baseline. Multivariable-adjusted Cox models were used to estimate associations between LE8 events. Over median 13.5 years follow-up, 11,134 incident events documented. Among APOs, incidence total significantly top tertile compared bottom tertile, HR (95% CI) 0.43 (0.29, 0.65). A similar trend observed an 0.55 (0.53, 0.58). With respect individual outcomes, among only coronary heart disease, for T3 vs T1: 0.30 (0.17, 0.55) atrial fibrillation, 0.47 (0.24, 0.91), achieved statistical significance. Women high had no 0.95 (0.63, 1.44). as using CVD, particularly disease fibrillation. The excess appears be attenuated those score.
Язык: Английский
Процитировано
0
American Journal of Preventive Cardiology, Год журнала: 2025, Номер unknown, С. 100994 - 100994
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0
Journal of Stroke and Cerebrovascular Diseases, Год журнала: 2025, Номер 34(3), С. 108238 - 108238
Опубликована: Янв. 12, 2025
This study aims to explore the association between Life's Essential 8 (LE8) and stroke all-cause mortality, compare whether it has an advantage over Simple 7 (LS7). investigated data from NHANES spanning 1999 2018. The LE8 was categorized as low, moderate high cardiovascular health (CVH). LS7 score inadequate, average, or optimal. Weighted logistic regression restricted cubic spline (RCS) were used examin correlations. Receiver operating characteristic (ROC) curves employed detect accuracy in predicting stroke. stratified sensitivity analyses conducted along with mediation analysis. In addition, a longitudinal cohort constructed by combining mortality data, Cox models utilized determine CVH rate. For LE8, compared low CVH, associated 41% lower risk of stroke, 71% prevalence LS7, inadequate average 24% optimal 39% RCS showed inverse dose-response relationships both unweighted ROC, (AUC=0.702, 95% CI: 0.685-0.718, P<0.001) stronger ability discriminate than (0.677, 0.658-0.696, (PDeLong=0.046). Sensitivity demonstrated robustness GGT WBC mediated 4.92% 4.58% association, respectively. neither nor predictive among survivor. outperformed classifying Oxidative stress inflammation
Язык: Английский
Процитировано
0
Frontiers in Medicine, Год журнала: 2025, Номер 12
Опубликована: Янв. 23, 2025
Objective This study aims to discuss the dose-response relationship between Life's Essential 8 (LE8) score and chronic obstructive pulmonary disease (COPD). Methods We screened data from National Health Nutrition Examination Survey (NHANES) database for years 2007–2018. Logistics regression analysis subgroup were used explore cardiovascular health (CVH) COPD based on LE8 score. Additionally, restricted cubic spline (RCS) plots drawn visually display relationship. Results A total of 12,517 participants included, which 835 had COPD. After multivariable adjustment, was found be linearly inversely associated with risk developing similar observed in scores behavior factors, whereas weaker factors. The RCS demonstrated aforementioned Moreover, analyses showed that this remained robust across different groups. Conclusion are Higher can reduce individuals over 40 old, especially concerning
Язык: Английский
Процитировано
0
International Journal of Rheumatic Diseases, Год журнала: 2025, Номер 28(2)
Опубликована: Фев. 1, 2025
ABSTRACT Background Life's Essential 8 (LE8) is a recently updated algorithm for evaluating cardiovascular health (CVH). This study investigates the association between LE8 and mortality risk among individuals with arthritis in United States. Methods We conducted retrospective cohort using data from US National Health Nutritional Examination Survey (NHANES) 2005–2018. Participants were included. Mortality data, including underlying causes of death, obtained through linkage to national death records up December 31, 2019. components (diet, physical activity, nicotine exposure, sleep, body mass index, blood lipids, glucose, pressure) measured scored 0 100. The total score, calculated as unweighted average all components, was categorized into low (0–49), moderate (50–79), high (80–100) CVH. employed Kaplan–Meier curves estimate survival probabilities weighted Cox proportional hazards regression models evaluate hazard ratios (HRs) 95% confidence intervals (CIs) all‐cause disease (CVD) mortality. Stratified analyses interaction tests performed explore potential effect modifications. Results Among 4519 participants (median follow‐up: 7.67 years), we observed 793 deaths, 213 CVD deaths. Every 10‐point increase score associated 17% lower (HR: 0.83, CI: 0.77–0.89) 25% 0.75, 0.66–0.85). Compared lowest CVH tertile, highest tertile demonstrated 38% 0.62, 0.41–0.92) 62% 0.38, 0.18–0.80). revealed significantly higher probability patients compared those (log‐rank p < 0.05). confirmed consistent associations across various subgroups. Similar findings sensitivity focusing on osteoarthritis other subtypes. Conclusion Higher adherence recommendations reduced risks adults arthritis.
Язык: Английский
Процитировано
0
The journal of nutrition health & aging, Год журнала: 2025, Номер 29(5), С. 100520 - 100520
Опубликована: Фев. 21, 2025
Diet plays a critical role in human health and environmental sustainability, particularly cardiovascular, kidney, metabolic (CKM) diseases. However, the variations Planetary Health Index (PHDI) across populations, regions, over time, as well its association with CKM disease burdens, remain insufficiently explored. We assessed PHDI scores using data from 185 countries (1990-2018) Global Dietary Database, examining demographic characteristics temporal trends. The Burden of Disease Study was used to evaluate associations between including incidence, prevalence, mortality, disability-adjusted life years. syndrome defined by American Heart Association. Individual-level National Nutrition Examination Survey (NHANES) were also assess impact on risks mortality. From 1990 2018, while overall remained relatively stable sexes, composition shifted different age groups. In mean score 42.80 (95% uncertainty interval [UI] 42.49-46.50) for males 44.65 UI 44.53-47.82) females. Higher observed among females, older adults, urban residents, individuals higher education, those South Asia. Globally, consumption red/processed meat, saturated oils/trans fats, added sugars substantially exceeded EAT-Lancet Commission's reference values. generally associated lower although these varied subtype. individual-level analysis, 45,460 NHANES participants (weighted age: 47.21 years, 51.4% female), each 10-point increase linked 13.7% reduction stage 3/4 risk, an 11.1% 4 incidences mortality rates cardiovascular diseases, chronic kidney disease. significant changes occurred components PHDI, notable demographics region. may reduce warranting further investigation into specific subtypes.
Язык: Английский
Процитировано
0