Biomaterials Science, Год журнала: 2023, Номер 11(17), С. 5769 - 5780
Опубликована: Янв. 1, 2023
Stimuli-responsive nanozymes with stimuli-switchable catalytic activities or stimuli-responsive release behaviors have unique applications in the fields of tumor therapy, antibacterial biosensing and anti-inflammatory therapy.
Язык: Английский
Nanoscale, Год журнала: 2023, Номер 15(28), С. 11813 - 11833
Опубликована: Янв. 1, 2023
The multi-modal therapy has superior anti-tumor efficacy to the uni-modal using nanoparticles inducing reactive oxygen species (ROS). multi-component nature of cold atmospheric plasma (CAP) enables excitation with a single treatment.
Язык: Английский
Процитировано
17
Nano Today, Год журнала: 2024, Номер 57, С. 102386 - 102386
Опубликована: Июль 13, 2024
Язык: Английский
Процитировано
6
Advanced Functional Materials, Год журнала: 2024, Номер unknown
Опубликована: Авг. 9, 2024
Abstract It is important but challenging to innovate inorganic sonosensitizers with controlled biodegradability and enhanced sonodynamic chemodynamic activities harness remodel the immunosuppressive tumor microenvironment (TME) for awakening robust immune responses against metastatic cancers. Herein rational design defect engineering strategy of a pH‐responsive biodegradable sonozyme system in sulfide nanocages augmented cancer immunotherapy reported. A series highly defective Co 9 S 8‐x elevated sulfur‐vacancy (V ) levels are fabricated systematically explore V ‐dependent properties by regulating weight ratio sulfur cobalt source. The bandgap substantially reduced from 2.06 1.54 eV, atomic 2+ 3+ increased 1.53 1.97. Therefore, sonodynamic, chemodynamic, antitumor dramatically system. slow degradation slightly acid TME size targeting infiltration, while exerting slight influence on performance. As result, satisfactory therapeutic effects eradication primary, distant, tumors can be achieved. This work highlights potential strategies combating
Язык: Английский
Процитировано
6
Acta Pharmaceutica Sinica B, Год журнала: 2022, Номер 13(7), С. 2926 - 2954
Опубликована: Дек. 31, 2022
Sonodynamic therapy (SDT) is an emerging noninvasive treatment modality that utilizes low-frequency and low-intensity ultrasound (US) to trigger sensitizers kill tumor cells with reactive oxygen species (ROS). Although SDT has attracted much attention for its properties including high specificity deep tissue penetration, anticancer efficacy still far from satisfactory. As a result, new strategies such as gas-assisted have been proposed further promote the effectiveness of SDT. In this review, mechanisms are first summarized. Then, applications cancer introduced categorized by gas types. Next, therapeutic systems can realize real-time imaging presented. Finally, challenges perspectives future clinical discussed.
Язык: Английский
Процитировано
27
Biomaterials Science, Год журнала: 2023, Номер 11(17), С. 5769 - 5780
Опубликована: Янв. 1, 2023
Stimuli-responsive nanozymes with stimuli-switchable catalytic activities or stimuli-responsive release behaviors have unique applications in the fields of tumor therapy, antibacterial biosensing and anti-inflammatory therapy.
Язык: Английский
Процитировано
13