Nanoscience & Nanotechnology-Asia,
Год журнала:
2024,
Номер
14(4)
Опубликована: Авг. 1, 2024
:
The
utilization
of
chemotherapy
remains
an
established
therapeutic
strategy
in
the
ongoing
fight
against
cancer.
Nevertheless,
it
has
been
impeded
by
occurrence
several
fatal
adverse
reactions
caused
non-specific
toxicity
often
associated
with
chemotherapy.
Nanotechnology
is
emerging
field
research
that
experiencing
rapid
growth
and
widely
recognized
as
a
highly
promising
approach
for
advanced
cancer
therapy.
Biosynthesized
green
nanomaterials
are
tools
treatment
diagnosis.
Metal
nanoparticles
have
developed
use
applications,
including
magnetically
sensitive
medication
delivery,
photothermal
treatment,
photoimaging.
Nanomaterials
containing
metals,
such
iron,
cobalt,
silver,
which
generated
from
various
bio-sources,
described.
boundless
capabilities
already
had
profound
impact
on
human
existence.
potential
effects
health
consistently
instilled
apprehension.
A
thorough
investigation
intricate
nature
facilitated
emergence
nanotoxicology,
examines
fundamental
origins
these
problems.
introduction
chemistry
principles
aimed
to
provide
safer
techniques
production
management
nanomaterials,
resulting
nanotechnology.
This
review
article
highlights
uses
nanotechnology
detection
tumors,
challenges
they
face
reaching
clinical
trials.
Biomedical Materials,
Год журнала:
2024,
Номер
19(5), С. 052008 - 052008
Опубликована: Авг. 22, 2024
Abstract
Soft-tissue
injuries
affecting
muscles,
nerves,
vasculature,
tendons,
and
ligaments
often
diminish
the
quality
of
life
due
to
pain,
loss
function,
financial
burdens.
Both
natural
healing
surgical
interventions
can
result
in
scarring,
which
potentially
may
impede
functional
recovery
lead
persistent
pain.
Scar
tissue,
characterized
by
a
highly
disorganized
fibrotic
extracellular
matrix,
serve
as
physical
barrier
regeneration
drug
delivery.
While
approaches
such
drugs,
biomaterials,
cells,
external
stimulation,
other
forces
show
promise
mitigating
scarring
promoting
regenerative
healing,
their
implementation
remains
limited
challenging.
Ultrasound,
laser,
electrical,
magnetic
forms
stimulation
have
been
utilized
promote
soft
tissue
well
neural
regeneration.
After
tissues
experience
increased
proliferation
Schwann
secretion
neurotropic
factors,
production
myelin,
growth
all
aimed
at
supporting
axon
innervation.
Yet,
outcomes
vary
depending
on
pathophysiology
damaged
nerve,
timing
following
injury,
specific
parameters
employed.
Increased
treatment
intensity
duration
noted
hinder
process
inducing
damage.
These
modalities,
either
alone
or
combination
with
nerve
guidance
conduits
scaffolds,
demonstrated
healing.
However,
literature
currently
lacks
detailed
understanding
used
for
applications.
In
this
article,
we
aim
address
gap
summarizing
existing
reports
providing
an
overview
alongside
associated
outcomes.
Journal of Materials Chemistry B,
Год журнала:
2024,
Номер
12(6), С. 1404 - 1428
Опубликована: Янв. 1, 2024
Magnetic
2D
nanocomposites
exhibit
advanced
antitumor
applications,
including
magnetically
targeted
hyperthermia,
drug
delivery,
phototherapy,
nanozyme
therapy,
immunotherapy
and
multimodal
imaging.
Research Square (Research Square),
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 26, 2025
Abstract
Iron
oxide
nanoparticles
have
gained
increasing
attention
in
various
biomedical
and
industrial
sectors
due
to
their
physicochemical
magnetic
properties.
In
this
study,
superparamagnetic
Fe3O4
with
small
particle
size
were
synthesized
by
co-precipitation
method,
coated
dextran,
modified
epoxy
functional
groups
1,4-butanediol
diglycidyl
ether.
The
prepared
composites
was
characterized
transmission
electron
microscopy,
thermogravimetry,
fourier
transform
infrared
spectroscopy,
X-ray
diffraction,and
vibrating
sample
magnetometry.
rat
serum
albumin
protein(rSA)
then
coupled
the
epoxide
group
on
nanoparticle
ability
of
conjugate
Protein
tested
BCA
Assay
Kit.
At
same
time,
we
used
CD4
antibody
detect
sorting
T
cells
flow
cytometry.
This
work
shows
that
our
epoxy-modified
iron
excellent
potential
applications
biology.
Frontiers in Human Neuroscience,
Год журнала:
2025,
Номер
19
Опубликована: Апрель 28, 2025
Neuromodulation,
the
targeted
regulation
of
nerve
activity,
has
emerged
as
a
promising
approach
for
treating
various
neurological
and
psychiatric
disorders.
While
deep
brain
stimulation
shown
efficacy,
its
invasive
nature
poses
substantial
risks,
including
surgical
complications
high
costs.
In
contrast,
non-invasive
neuromodulation
techniques,
particularly
those
utilizing
magnetic
fields
(MFs),
have
gained
increasing
attention
safer,
more
accessible
alternatives.
Magnetothermal
an
innovative
method
that
enables
precise
modulation
neuronal
ion
channels
through
localized
heating
induced
by
interaction
MF
with
biological
tissues.
This
review
discusses
principles
MF-based
highlights
critical
role
in
synaptic
transmission,
therapeutic
potential
these
advanced
techniques.
Additionally,
it
key
challenges
such
spatial
targeting
precision,
safety
considerations,
long-term
effects
exposure
on
function.
The
findings
presente
promise
non-invasive,
highly
strategy
conditions
epilepsy,
movement
disorders,
neurodegenerative
diseases,
applications
chronic
pain
management
future
clinical
interventions.
Molecules,
Год журнала:
2024,
Номер
29(8), С. 1848 - 1848
Опубликована: Апрель 18, 2024
In
recent
years,
the
frequency
of
strokes
has
been
on
rise
year
by
and
become
second
leading
cause
death
around
world,
which
is
characterized
a
high
mortality
rate,
recurrence
disability
rate.
Ischemic
account
for
large
percentage
strokes.
A
reperfusion
injury
in
ischemic
complex
cascade
oxidative
stress,
neuroinflammation,
immune
infiltration,
mitochondrial
damage.
Conventional
treatments
are
ineffective,
presence
blood–brain
barrier
(BBB)
leads
to
inefficient
drug
delivery
utilization,
so
researchers
turning
their
attention
nano-drug
systems.
Functionalized
systems
have
widely
studied
applied
study
cerebral
diseases
due
favorable
biocompatibility,
efficiency,
strong
specificity,
specific
targeting
ability.
this
paper,
we
briefly
describe
pathological
process
injuries
focus
therapeutic
research
progress
strokes,
aiming
provide
certain
references
understand
(NDDSs).