Green-synthesized Metal Nanoparticles for Cancer Diagnosis and Treatment: A Critical Review DOI
Ravindra Waykar,

Srinivasakumar Kumarapillai,

Yogesh A. Kulkarni

и другие.

Nanoscience &amp Nanotechnology-Asia, Год журнала: 2024, Номер 14(4)

Опубликована: Авг. 1, 2024

: The utilization of chemotherapy remains an established therapeutic strategy in the ongoing fight against cancer. Nevertheless, it has been impeded by occurrence several fatal adverse reactions caused non-specific toxicity often associated with chemotherapy. Nanotechnology is emerging field research that experiencing rapid growth and widely recognized as a highly promising approach for advanced cancer therapy. Biosynthesized green nanomaterials are tools treatment diagnosis. Metal nanoparticles have developed use applications, including magnetically sensitive medication delivery, photothermal treatment, photoimaging. Nanomaterials containing metals, such iron, cobalt, silver, which generated from various bio-sources, described. boundless capabilities already had profound impact on human existence. potential effects health consistently instilled apprehension. A thorough investigation intricate nature facilitated emergence nanotoxicology, examines fundamental origins these problems. introduction chemistry principles aimed to provide safer techniques production management nanomaterials, resulting nanotechnology. This review article highlights uses nanotechnology detection tumors, challenges they face reaching clinical trials.

Язык: Английский

Advancements in stimulation therapies for peripheral nerve regeneration DOI
Rosalie Bordett,

Khadija Basiru Danazumi,

Suranji Wijekoon

и другие.

Biomedical Materials, Год журнала: 2024, Номер 19(5), С. 052008 - 052008

Опубликована: Авг. 22, 2024

Abstract Soft-tissue injuries affecting muscles, nerves, vasculature, tendons, and ligaments often diminish the quality of life due to pain, loss function, financial burdens. Both natural healing surgical interventions can result in scarring, which potentially may impede functional recovery lead persistent pain. Scar tissue, characterized by a highly disorganized fibrotic extracellular matrix, serve as physical barrier regeneration drug delivery. While approaches such drugs, biomaterials, cells, external stimulation, other forces show promise mitigating scarring promoting regenerative healing, their implementation remains limited challenging. Ultrasound, laser, electrical, magnetic forms stimulation have been utilized promote soft tissue well neural regeneration. After tissues experience increased proliferation Schwann secretion neurotropic factors, production myelin, growth all aimed at supporting axon innervation. Yet, outcomes vary depending on pathophysiology damaged nerve, timing following injury, specific parameters employed. Increased treatment intensity duration noted hinder process inducing damage. These modalities, either alone or combination with nerve guidance conduits scaffolds, demonstrated healing. However, literature currently lacks detailed understanding used for applications. In this article, we aim address gap summarizing existing reports providing an overview alongside associated outcomes.

Язык: Английский

Процитировано

5

Multifunctional role of nanoparticles for the diagnosis and therapeutics of cardiovascular diseases DOI

Ihtesham Arshad,

Ayesha Kanwal, Imran Zafar

и другие.

Environmental Research, Год журнала: 2023, Номер 242, С. 117795 - 117795

Опубликована: Дек. 2, 2023

Язык: Английский

Процитировано

12

Magnetic two-dimensional nanocomposites for multimodal antitumor therapy: a recent review DOI Open Access
Ying Yuan, Bo Chen,

Luping Song

и другие.

Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(6), С. 1404 - 1428

Опубликована: Янв. 1, 2024

Magnetic 2D nanocomposites exhibit advanced antitumor applications, including magnetically targeted hyperthermia, drug delivery, phototherapy, nanozyme therapy, immunotherapy and multimodal imaging.

Язык: Английский

Процитировано

4

Green synthesis of copper oxide nanoparticles using Rosmarinus officinalis leaf extract and evaluation of its antimicrobial activity DOI

Mekides Dinka Moroda,

Tolesa Leta Deressa,

Ardila Hayu Tiwikrama

и другие.

Next Materials, Год журнала: 2024, Номер 7, С. 100337 - 100337

Опубликована: Авг. 5, 2024

Язык: Английский

Процитировано

4

Hybrid Lymphatic Drug Delivery Vehicles as a New Avenue for Targeted Therapy: Lymphatic Trafficking, Applications, Challenges, and Future Horizons DOI Open Access
Gamaleldin I. Harisa, Abdelrahman Y. Sherif,

Fars K. Alanazi

и другие.

The Journal of Membrane Biology, Год журнала: 2023, Номер 256(3), С. 199 - 222

Опубликована: Фев. 8, 2023

Язык: Английский

Процитировано

11

Epoxy functionalized small particle size superparamagnetic iron oxide nanoparticles for CD4+T cell sorting DOI Creative Commons
Yiyang Zhou,

Wei Dong

Research Square (Research Square), Год журнала: 2025, Номер unknown

Опубликована: Фев. 26, 2025

Abstract Iron oxide nanoparticles have gained increasing attention in various biomedical and industrial sectors due to their physicochemical magnetic properties. In this study, superparamagnetic Fe3O4 with small particle size were synthesized by co-precipitation method, coated dextran, modified epoxy functional groups 1,4-butanediol diglycidyl ether. The prepared composites was characterized transmission electron microscopy, thermogravimetry, fourier transform infrared spectroscopy, X-ray diffraction,and vibrating sample magnetometry. rat serum albumin protein(rSA) then coupled the epoxide group on nanoparticle ability of conjugate Protein tested BCA Assay Kit. At same time, we used CD4 antibody detect sorting T cells flow cytometry. This work shows that our epoxy-modified iron excellent potential applications biology.

Язык: Английский

Процитировано

0

Antibacterial Surface Functionalization of Biomedical Scaffolds: a Transformation towards More Adaptive, Resilient Regenerative Therapy DOI Creative Commons
Ika Dewi Ana, Nihal Engin Vrana, Aryan Morita

и другие.

Results in Surfaces and Interfaces, Год журнала: 2025, Номер unknown, С. 100481 - 100481

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Degradation of tetracycline by magnetic BiOI/S-doped g-C3N4/NiFe2O4 nanocomposite through visible-light photocatalysis process DOI

Zahra Mahdavi,

Ali Akbar Amooey,

Shahram Ghasemi

и другие.

Diamond and Related Materials, Год журнала: 2025, Номер unknown, С. 112306 - 112306

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0

Advances in magnetic field approaches for non-invasive targeting neuromodulation DOI Creative Commons
Mozhgan Alipour,

Maryam Abdolmaleki,

Yaser Shabanpour

и другие.

Frontiers in Human Neuroscience, Год журнала: 2025, Номер 19

Опубликована: Апрель 28, 2025

Neuromodulation, the targeted regulation of nerve activity, has emerged as a promising approach for treating various neurological and psychiatric disorders. While deep brain stimulation shown efficacy, its invasive nature poses substantial risks, including surgical complications high costs. In contrast, non-invasive neuromodulation techniques, particularly those utilizing magnetic fields (MFs), have gained increasing attention safer, more accessible alternatives. Magnetothermal an innovative method that enables precise modulation neuronal ion channels through localized heating induced by interaction MF with biological tissues. This review discusses principles MF-based highlights critical role in synaptic transmission, therapeutic potential these advanced techniques. Additionally, it key challenges such spatial targeting precision, safety considerations, long-term effects exposure on function. The findings presente promise non-invasive, highly strategy conditions epilepsy, movement disorders, neurodegenerative diseases, applications chronic pain management future clinical interventions.

Язык: Английский

Процитировано

0

Advanced Nano-Drug Delivery Systems in the Treatment of Ischemic Stroke DOI Creative Commons
Jiangjun Zhang, Zhong Chen, Qi Chen

и другие.

Molecules, Год журнала: 2024, Номер 29(8), С. 1848 - 1848

Опубликована: Апрель 18, 2024

In recent years, the frequency of strokes has been on rise year by and become second leading cause death around world, which is characterized a high mortality rate, recurrence disability rate. Ischemic account for large percentage strokes. A reperfusion injury in ischemic complex cascade oxidative stress, neuroinflammation, immune infiltration, mitochondrial damage. Conventional treatments are ineffective, presence blood–brain barrier (BBB) leads to inefficient drug delivery utilization, so researchers turning their attention nano-drug systems. Functionalized systems have widely studied applied study cerebral diseases due favorable biocompatibility, efficiency, strong specificity, specific targeting ability. this paper, we briefly describe pathological process injuries focus therapeutic research progress strokes, aiming provide certain references understand (NDDSs).

Язык: Английский

Процитировано

3