Green-synthesized Metal Nanoparticles for Cancer Diagnosis and Treatment: A Critical Review DOI
Ravindra Waykar,

Srinivasakumar Kumarapillai,

Yogesh A. Kulkarni

et al.

Nanoscience &amp Nanotechnology-Asia, Journal Year: 2024, Volume and Issue: 14(4)

Published: Aug. 1, 2024

: The utilization of chemotherapy remains an established therapeutic strategy in the ongoing fight against cancer. Nevertheless, it has been impeded by occurrence several fatal adverse reactions caused non-specific toxicity often associated with chemotherapy. Nanotechnology is emerging field research that experiencing rapid growth and widely recognized as a highly promising approach for advanced cancer therapy. Biosynthesized green nanomaterials are tools treatment diagnosis. Metal nanoparticles have developed use applications, including magnetically sensitive medication delivery, photothermal treatment, photoimaging. Nanomaterials containing metals, such iron, cobalt, silver, which generated from various bio-sources, described. boundless capabilities already had profound impact on human existence. potential effects health consistently instilled apprehension. A thorough investigation intricate nature facilitated emergence nanotoxicology, examines fundamental origins these problems. introduction chemistry principles aimed to provide safer techniques production management nanomaterials, resulting nanotechnology. This review article highlights uses nanotechnology detection tumors, challenges they face reaching clinical trials.

Language: Английский

Magnetic two-dimensional nanocomposites for multimodal antitumor therapy: a recent review DOI Open Access
Ying Yuan, Bo Chen,

Luping Song

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(6), P. 1404 - 1428

Published: Jan. 1, 2024

Magnetic 2D nanocomposites exhibit advanced antitumor applications, including magnetically targeted hyperthermia, drug delivery, phototherapy, nanozyme therapy, immunotherapy and multimodal imaging.

Language: Английский

Citations

4
Roadmap on magnetic nanoparticles in nanomedicine DOI Creative Commons
Kai Wu, Jian‐Ping Wang, Niranjan A. Natekar

et al.

Nanotechnology, Journal Year: 2024, Volume and Issue: 36(4), P. 042003 - 042003

Published: Oct. 12, 2024

Abstract Magnetic nanoparticles (MNPs) represent a class of small particles typically with diameters ranging from 1 to 100 nanometers. These are composed magnetic materials such as iron, cobalt, nickel, or their alloys. The nanoscale size MNPs gives them unique physicochemical (physical and chemical) properties not found in bulk counterparts. Their versatile nature behavior make valuable wide range scientific, medical, technological fields. Over the past decade, there has been significant surge MNP-based applications spanning biomedical uses, environmental remediation, data storage, energy catalysis. Given size, can be manipulated guided using external This characteristic is harnessed applications, where these directed specific targets body for imaging, drug delivery, hyperthermia treatment. Herein, this roadmap offers an overview current status, challenges, advancements various facets MNPs. It covers properties, synthesis, functionalization, characterization, sample enrichment, bioassays, hyperthermia, neuromodulation, tissue engineering, drug/gene delivery. However, increasingly explored vivo concerns have emerged regarding cytotoxicity, cellular uptake, degradation, prompting attention both researchers clinicians. aims provide comprehensive perspective on evolving landscape MNP research.

Language: Английский

Citations

4
Epoxy functionalized small particle size superparamagnetic iron oxide nanoparticles for CD4+T cell sorting DOI Creative Commons
Yiyang Zhou,

Wei Dong

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 26, 2025

Abstract Iron oxide nanoparticles have gained increasing attention in various biomedical and industrial sectors due to their physicochemical magnetic properties. In this study, superparamagnetic Fe3O4 with small particle size were synthesized by co-precipitation method, coated dextran, modified epoxy functional groups 1,4-butanediol diglycidyl ether. The prepared composites was characterized transmission electron microscopy, thermogravimetry, fourier transform infrared spectroscopy, X-ray diffraction,and vibrating sample magnetometry. rat serum albumin protein(rSA) then coupled the epoxide group on nanoparticle ability of conjugate Protein tested BCA Assay Kit. At same time, we used CD4 antibody detect sorting T cells flow cytometry. This work shows that our epoxy-modified iron excellent potential applications biology.

Language: Английский

Citations

0
Antibacterial Surface Functionalization of Biomedical Scaffolds: a Transformation towards More Adaptive, Resilient Regenerative Therapy DOI Creative Commons
Ika Dewi Ana, Nihal Engin Vrana, Aryan Morita

et al.

Results in Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: unknown, P. 100481 - 100481

Published: March 1, 2025

Language: Английский

Citations

0
Enhancing dementia diagnosis with Dual-Swarm optimisation and Opposition-Based learning: the DSO-OBL approach DOI

D. Kavitha,

A. Murugan

Journal of Experimental & Theoretical Artificial Intelligence, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 26

Published: April 5, 2025

Language: Английский

Citations

0
Degradation of tetracycline by magnetic BiOI/S-doped g-C3N4/NiFe2O4 nanocomposite through visible-light photocatalysis process DOI

Zahra Mahdavi,

Ali Akbar Amooey,

Shahram Ghasemi

et al.

Diamond and Related Materials, Journal Year: 2025, Volume and Issue: unknown, P. 112306 - 112306

Published: April 1, 2025

Language: Английский

Citations

0
Advances in magnetic field approaches for non-invasive targeting neuromodulation DOI Creative Commons
Mozhgan Alipour,

Maryam Abdolmaleki,

Yaser Shabanpour

et al.

Frontiers in Human Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: April 28, 2025

Neuromodulation, the targeted regulation of nerve activity, has emerged as a promising approach for treating various neurological and psychiatric disorders. While deep brain stimulation shown efficacy, its invasive nature poses substantial risks, including surgical complications high costs. In contrast, non-invasive neuromodulation techniques, particularly those utilizing magnetic fields (MFs), have gained increasing attention safer, more accessible alternatives. Magnetothermal an innovative method that enables precise modulation neuronal ion channels through localized heating induced by interaction MF with biological tissues. This review discusses principles MF-based highlights critical role in synaptic transmission, therapeutic potential these advanced techniques. Additionally, it key challenges such spatial targeting precision, safety considerations, long-term effects exposure on function. The findings presente promise non-invasive, highly strategy conditions epilepsy, movement disorders, neurodegenerative diseases, applications chronic pain management future clinical interventions.

Language: Английский

Citations

0
Hybrid Lymphatic Drug Delivery Vehicles as a New Avenue for Targeted Therapy: Lymphatic Trafficking, Applications, Challenges, and Future Horizons DOI Open Access
Gamaleldin I. Harisa, Abdelrahman Y. Sherif,

Fars K. Alanazi

et al.

The Journal of Membrane Biology, Journal Year: 2023, Volume and Issue: 256(3), P. 199 - 222

Published: Feb. 8, 2023

Language: Английский

Citations

10
Multifunctional role of nanoparticles for the diagnosis and therapeutics of cardiovascular diseases DOI

Ihtesham Arshad,

Ayesha Kanwal, Imran Zafar

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 242, P. 117795 - 117795

Published: Dec. 2, 2023

Language: Английский

Citations

10
Advanced Nano-Drug Delivery Systems in the Treatment of Ischemic Stroke DOI Creative Commons
Jiangjun Zhang, Zhong Chen, Qi Chen

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(8), P. 1848 - 1848

Published: April 18, 2024

In recent years, the frequency of strokes has been on rise year by and become second leading cause death around world, which is characterized a high mortality rate, recurrence disability rate. Ischemic account for large percentage strokes. A reperfusion injury in ischemic complex cascade oxidative stress, neuroinflammation, immune infiltration, mitochondrial damage. Conventional treatments are ineffective, presence blood–brain barrier (BBB) leads to inefficient drug delivery utilization, so researchers turning their attention nano-drug systems. Functionalized systems have widely studied applied study cerebral diseases due favorable biocompatibility, efficiency, strong specificity, specific targeting ability. this paper, we briefly describe pathological process injuries focus therapeutic research progress strokes, aiming provide certain references understand (NDDSs).

Language: Английский

Citations

3