Journal of Comparative Physiology A,
Год журнала:
2023,
Номер
210(4), С. 585 - 599
Опубликована: Авг. 16, 2023
Abstract
Organisms
adapt
to
unfavorable
seasonal
conditions
survive.
These
adaptations
rely
on
the
correct
interpretation
of
environmental
cues
such
as
photoperiod,
and
temperature.
Genetic
studies
in
several
organisms,
including
genetic
powerhouse
Drosophila
melanogaster
,
indicate
that
circadian
clock
components,
period
timeless
are
involved
photoperiodic-dependent
adaptations,
but
our
understanding
this
process
is
far
from
complete.
In
particular,
role
temperature
a
key
factor
complement
photoperiodic
response
not
well
understood.
The
development
new
sequencing
technologies
has
proven
extremely
useful
plastic
changes
other
cellular
components
undergo
different
conditions,
gene
expression
alternative
splicing.
This
article
discusses
integration
photoperiod
for
biology
downstream
molecular
pathways
regulation
physiological
occur
with
changing
seasons.
We
focus
discussion
current
involvement
neuronal
circuits
these
D.
.
Biochemical Society Transactions,
Год журнала:
2023,
Номер
51(5), С. 1847 - 1856
Опубликована: Окт. 6, 2023
Diapause
is
a
protective
mechanism
that
many
organisms
deploy
to
overcome
environmental
adversities.
extends
lifespan
and
fertility
enhance
the
reproductive
success
survival
of
species.
Although
diapause
states
have
been
known
employed
for
commercial
purposes,
example
in
silk
industry,
detailed
molecular
cell
biological
studies
are
an
exciting
frontier.
Understanding
diapause-like
mechanisms
will
shed
light
on
pathways
steer
through
adverse
conditions.
One
hope
understanding
support
might
be
leveraged
extend
and/or
health
span
humans
as
well
species
threatened
by
climate
change.
In
addition,
recent
findings
suggest
cancer
cells
persist
after
treatment
mimic
states,
implying
these
programs
may
facilitate
from
chemotherapy
cause
relapse.
Here,
we
review
underlying
variety
organisms,
discuss
supporting
tumor
persister
cells.
Host-microbe
interactions
underlie
the
development
and
fitness
of
many
macroorganisms,
including
bees.
Whereas
social
bees
benefit
from
vertically
transmitted
gut
bacteria,
current
data
suggests
that
solitary
bees,
which
comprise
vast
majority
species
diversity
within
lack
a
highly
specialized
microbiome.
Here,
we
examine
composition
abundance
bacteria
fungi
throughout
complete
life
cycle
ground-nesting
bee
Anthophora
bomboides
standfordiana.
In
contrast
to
expectations,
immature
stages
maintain
distinct
core
microbiome
consisting
Actinobacterial
genera
(Streptomyces,
Nocardiodes)
fungus
Moniliella
spathulata.
Dormant
(diapausing)
larval
hosted
most
abundant
distinctive
fungi,
attaining
33
52
times
their
initial
copy
number,
respectively.
We
tested
two
adaptive
hypotheses
regarding
microbial
functions
for
diapausing
First,
using
isolated
found
Streptomyces
brood
cells
inhibited
growth
multiple
pathogenic
filamentous
suggesting
role
in
pathogen
protection
during
overwintering,
when
face
high
pressure.
Second,
sugar
alcohol
changed
tandem
with
major
changes
fungal
abundance,
links
cold
tolerance
or
overwintering
biology.
find
A.
hosts
conserved
may
provide
key
advantages
through
diapause,
raises
question
how
this
is
maintained
faithfully
between
generations.
Our
results
suggest
focus
on
microbiomes
mature
active
insect
developmental
overlook
stage-specific
symbionts
contributions
host
dormancy.
Proceedings of the National Academy of Sciences,
Год журнала:
2024,
Номер
121(27)
Опубликована: Июнь 25, 2024
To
survive
adverse
environments,
many
animals
enter
a
dormant
state
such
as
hibernation,
dauer,
or
diapause.
Various
Drosophila
species
undergo
adult
reproductive
diapause
in
response
to
cool
temperatures
and/or
short
day-length.
While
flies
are
less
active
during
diapause,
it
is
unclear
how
environmental
conditions
affect
circadian
rhythms
and
sleep.
Here
we
show
that
diapause-inducing
temperatures,
melanogaster
exhibit
altered
activity
profiles,
including
severely
reduced
morning
an
advanced
evening
peak.
Consequently,
the
have
single
peak
at
time
similar
when
nondiapausing
take
siesta.
Temperatures
≤15
°C,
rather
than
photoperiod,
primarily
drive
this
behavior.
At
rapidly
deep-sleep
lacks
sleep
cycles
of
higher
require
high
levels
stimulation
for
arousal.
Furthermore,
25
prefer
siesta
shade,
preference
virtually
eliminated
10
°C.
Resting
shade
driven
by
aversion
blue
light
sensed
Rhodopsin
7
outside
eyes.
Flies
°C
neuronal
markers
elevated
pressure,
increased
expression
Bruchpilot
Ca
2+
R5
ellipsoid
body
neurons.
Therefore,
pressure
might
overcome
aversion.
Thus,
same
cause
arrest,
preserve
germline
stem
cells,
extend
lifespan,
D.
prone
deep
dramatically
altered,
yet
rhythmic,
daily
patterns.
iScience,
Год журнала:
2025,
Номер
28(3), С. 111761 - 111761
Опубликована: Янв. 7, 2025
Diapause
enables
insects
to
survive
unfavorable
conditions
through
metabolic
and
developmental
adjustments.
We
investigated
regulation
during
reproductive
diapause
in
the
predatory
stinkbug
Arma
chinensis
using
transcriptomic
metabolomic
analyses.
Our
study
revealed
9,254
differentially
expressed
genes
493
significantly
changed
metabolites
across
stages.
Key
pathways
including
glutathione
metabolism,
TCA
cycle,
glycolysis,
lipid
metabolism
underwent
substantial
reorganization.
The
pre-diapause
phase
showed
increased
energy
consumption
accumulation,
while
maintenance
exhibited
restructuring
of
amino
acid
glucose
metabolism.
identified
stage-specific
signatures
potential
regulatory
mechanisms,
roles
redox
insulin
signaling
control.
This
comprehensive
characterization
reprogramming
A.
provides
insights
for
improving
biocontrol
agent
production
storage
strategies.
