Neural Networks, Год журнала: 2024, Номер 180, С. 106714 - 106714
Опубликована: Сен. 7, 2024
Язык: Английский
bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2023, Номер unknown
Опубликована: Июнь 26, 2023
Summary Different theories explain how subjective experience arises from brain activity 1,2 . These have independently accrued evidence, yet, confirmation bias and dependence on design choices hamper progress in the field 3 Here, we present an open science adversarial collaboration which directly juxtaposes Integrated Information Theory (IIT) 4,5 Global Neuronal Workspace (GNWT) 6–10 , employing a theory-neutral consortium approach 11,12 We investigate neural correlates of content duration visual experience. The theory proponents developed preregistered experimental design, divergent predictions, expected outcomes, their interpretation 12 256 human subjects viewed suprathreshold stimuli for variable durations while was measured with functional magnetic resonance imaging, magnetoencephalography, electrocorticography. find information about conscious visual, ventro-temporal inferior frontal cortex, sustained responses occipital lateral temporal cortex reflecting stimulus duration, content-specific synchronization between early areas. results confirm some predictions IIT GNWT, substantially challenging both theories: IIT, lack within posterior contradicts claim that network connectivity specifies consciousness. GNWT is challenged by general ignition at offset limited representation certain dimensions prefrontal cortex. Beyond themselves, alternative to advance cognitive neuroscience through principled, theory-driven, collaborative effort. highlight challenges change people’s mind 13 need quantitative framework integrating evidence systematic testing building.
Язык: Английский
Процитировано
53
Neuron, Год журнала: 2024, Номер 112(10), С. 1531 - 1552
Опубликована: Март 5, 2024
How is conscious experience related to material brain processes? A variety of theories aiming answer this age-old question have emerged from the recent surge in consciousness research, and some are now hotly debated. Although most researchers so far focused on development validation their preferred theory relative isolation, article, written by a group scientists representing different theories, takes an alternative approach. Noting that various often try explain aspects or mechanistic levels consciousness, we argue do not necessarily contradict each other. Instead, several them may converge fundamental neuronal mechanisms be partly compatible complementary, multiple can simultaneously contribute our understanding. Here, consider unifying, integration-oriented approaches been largely neglected, seeking combine valuable elements theories.
Язык: Английский
Процитировано
36
Neuron, Год журнала: 2024, Номер 112(10), С. 1568 - 1594
Опубликована: Май 1, 2024
Язык: Английский
Процитировано
22
Neuron, Год журнала: 2024, Номер 112(10), С. 1553 - 1567
Опубликована: Апрель 4, 2024
Язык: Английский
Процитировано
20
Nature Neuroscience, Год журнала: 2025, Номер unknown
Опубликована: Март 10, 2025
Язык: Английский
Процитировано
2
eLife, Год журнала: 2023, Номер 12
Опубликована: Июль 25, 2023
How is the information-processing architecture of human brain organised, and how does its organisation support consciousness? Here, we combine network science a rigorous information-theoretic notion synergy to delineate ‘synergistic global workspace’, comprising gateway regions that gather synergistic information from specialised modules across brain. This then integrated within workspace widely distributed via broadcaster regions. Through functional MRI analysis, show correspond brain’s default mode network, whereas broadcasters coincide with executive control network. We find loss consciousness due general anaesthesia or disorders corresponds diminished ability integrate information, which restored upon recovery. Thus, coincides breakdown integration work contributes conceptual empirical reconciliation between two prominent scientific theories consciousness, Global Neuronal Workspace Integrated Information Theory, while also advancing our understanding supports through information.
Язык: Английский
Процитировано
31
Consciousness and Cognition, Год журнала: 2024, Номер 119, С. 103653 - 103653
Опубликована: Фев. 28, 2024
Recent activities in virtually all fields engaged consciousness studies indicate early signs of a structural turn, where verbal descriptions or simple formalisations conscious experiences are replaced by tools, most notably mathematical spaces. My goal here is to offer three comments that, my opinion, essential avoid misunderstandings these developments on. These concern metaphysical premises approaches, the viability structure-preserving mappings, and question what structure experience first place. I will also explain what, great promises methodologies how they might impact science at large.
Язык: Английский
Процитировано
13
Neuroscience & Biobehavioral Reviews, Год журнала: 2025, Номер unknown, С. 106053 - 106053
Опубликована: Фев. 1, 2025
As the field of consciousness science matures, research agenda has expanded from an initial focus on neural correlates consciousness, to developing and testing theories consciousness. Several have been put forward, each aiming elucidate relationship between brain function. However, there is ongoing, intense debate regarding whether these examine same phenomenon. And, despite ongoing efforts, it seems like so far failed converge around any single theory, instead exhibits significant polarization. To advance this discussion, proponents five prominent consciousness-Global Neuronal Workspace Theory (GNWT), Higher-Order Theories (HOT), Integrated Information (IIT), Recurrent Processing (RPT), Predictive (PP)-engaged in a public 2022, as part annual meeting Association for Scientific Study Consciousness (ASSC). They were invited clarify explananda their theories, articulate core mechanisms underpinning corresponding explanations, outline foundational premises. This was followed by open discussion that delved into testability potential evidence could refute them, areas consensus disagreement. Most importantly, demonstrated at stage, more controversy than agreement pertaining most basic questions what is, how identify conscious states, required theory Addressing crucial advancing towards deeper understanding comparison competing theories.
Язык: Английский
Процитировано
1
PLoS ONE, Год журнала: 2025, Номер 20(2), С. e0318863 - e0318863
Опубликована: Фев. 27, 2025
A major debate in the field of consciousness pertains to whether neuronal activity or rather causal structure neural circuits underlie generation conscious experience. The former position is held by theoretical accounts based on predictive processing framework (such as neurorepresentationalism and active inference), while latter posited integrated information theory. This protocol describes an experiment, part a larger adversarial collaboration, that was designed address this question through combination behavioral tests mice, functional imaging, patterned optogenetics electrophysiology. experiment will directly test if optogenetic inactivation portion visual cortex not responding behaviorally relevant stimuli affect perception spatial distribution these stimuli, even when neurons being inactivated display no very low spiking activity, so it does induce significant effect other cortical areas. results be compared against predictions, provide contribution towards understanding what substrate is.
Язык: Английский
Процитировано
1
Nature Neuroscience, Год журнала: 2025, Номер unknown
Опубликована: Март 10, 2025
Язык: Английский
Процитировано
1