bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Ноя. 10, 2023
Abstract
A
major
barrier
for
most
fungal
species
to
infect
humans
is
their
inability
grow
at
body
temperature
(37°C).
Global
warming
and
more
frequent
extreme
heat
events
may
impose
selection
pressures
that
allow
adaptation
higher
temperatures.
Cities
are
islands
up
8°C
warmer
than
suburban
counterparts
because
of
mechanical
production
reduced
greenspace,
among
other
factors,
be
an
important
reservoir
fungi
have
increased
risk
thermotolerance
inhabit
environments
near
humans.
Here
we
describe
a
novel
inexpensive
technique
was
developed
collect
samples
from
various
sites
in
Baltimore,
Maryland
using
commercially
available
taffy
candy.
Our
results
show
isolates
neighborhoods
greater
lighter
pigmentation
relative
the
same
cooler
neighborhoods,
suggesting
local
adaptation.
Lighter
areas
consistent
with
known
mechanisms
pigment
regulation
modulate
cell
temperature.
The
opportunistic
pathogen
Rhodotorula
mucilaginosa
had
resistance
gradual
exposure
those
neighborhoods.
imply
urban
environment.
acquisition
poses
if
pathogenic
potential
acquire
capacity
human
temperatures
cause
disease.
BMC Infectious Diseases,
Год журнала:
2024,
Номер
24(1)
Опубликована: Июнь 26, 2024
Malassezia
restricta,
a
lipophilic
and
lipodependent
yeast
belonging
to
the
basidiomycetes
group,
is
an
opportunistic
fungal
pathogen
associated
with
various
skin
diseases,
including
seborrheic
dermatitis
dandruff.
Typically,
infection
in
neonates
manifests
as
fungemia
or
hematogenous
dissemination
bone
lungs.
However,
vertebral
osteomyelitis
caused
by
these
fungi
rarely
reported
owing
non-specific
clinical
presentations
laboratory/imaging
findings.
The
Pathogen
Metagenomics
Sequencing
(PMseq)
technique
enables
direct
high-throughput
sequencing
of
infected
specimens,
facilitating
rapid
accurate
detection
all
microorganisms
samples
through
comprehensive
reports.
The
epidemiology
and
clinical
impact
of
COVID-19-associated
candidemia
(CAC)
remained
uncertain,
leaving
gaps
in
understanding
its
prevalence,
risk
factors
outcomes.
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Ноя. 10, 2023
Abstract
A
major
barrier
for
most
fungal
species
to
infect
humans
is
their
inability
grow
at
body
temperature
(37°C).
Global
warming
and
more
frequent
extreme
heat
events
may
impose
selection
pressures
that
allow
adaptation
higher
temperatures.
Cities
are
islands
up
8°C
warmer
than
suburban
counterparts
because
of
mechanical
production
reduced
greenspace,
among
other
factors,
be
an
important
reservoir
fungi
have
increased
risk
thermotolerance
inhabit
environments
near
humans.
Here
we
describe
a
novel
inexpensive
technique
was
developed
collect
samples
from
various
sites
in
Baltimore,
Maryland
using
commercially
available
taffy
candy.
Our
results
show
isolates
neighborhoods
greater
lighter
pigmentation
relative
the
same
cooler
neighborhoods,
suggesting
local
adaptation.
Lighter
areas
consistent
with
known
mechanisms
pigment
regulation
modulate
cell
temperature.
The
opportunistic
pathogen
Rhodotorula
mucilaginosa
had
resistance
gradual
exposure
those
neighborhoods.
imply
urban
environment.
acquisition
poses
if
pathogenic
potential
acquire
capacity
human
temperatures
cause
disease.
