Antiviral and antibacterial properties of phloroglucinols: a review on naturally occurring and (semi)synthetic derivatives with potential therapeutic interest DOI
Gregorio Peron,

Alice M. López,

Paulina Cabada-Aguirre

и другие.

Critical Reviews in Biotechnology, Год журнала: 2023, Номер 44(2), С. 319 - 336

Опубликована: Янв. 2, 2023

Phloroglucinol and derived compounds comprise a huge class of secondary metabolites widely distributed in plants brown algae. A vast array biological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer has been associated to this compounds. In review, the available data on antiviral antibacterial capacity phloroglucinols have analyzed. Some these derivatives show important antimicrobial properties vitro. Phloroglucinols shown be effective against viruses, such as human immunodeficiency virus (HIV), herpes or enterovirus, preliminary through docking analysis suggest that they can SARS-CoV-19. Also, some effects diverse bacteria strains, Bacillus subtilis Staphylococcus aureus, (semi)synthetic development novel led with significantly increased activity. However, therapeutic use is hindered by absence vivo studies scarcity information their mechanisms action, hence further research efforts are required. On basis consideration, our work aims gather regarding efficacy natural-occurring synthetic phloroglucinol agents pathogens, which published during last three decades. The recollection results reported review represents valuable source updated will potentially help researchers agents.

Язык: Английский

Therapeutic Potential of Polyphenols and Other Micronutrients of Marine Origin DOI Creative Commons
Leonel Pereira, João Cotas

Marine Drugs, Год журнала: 2023, Номер 21(6), С. 323 - 323

Опубликована: Май 26, 2023

Polyphenols are compounds found in various plants and foods, known for their antioxidant anti-inflammatory properties. Recently, researchers have been exploring the therapeutic potential of marine polyphenols other minor nutrients that algae, fish crustaceans. These unique chemical structures exhibit diverse biological properties, including anti-inflammatory, antioxidant, antimicrobial antitumor action. Due to these being investigated as possible agents treatment a wide variety conditions, such cardiovascular disease, diabetes, neurodegenerative diseases cancer. This review focuses on applications human health, also, phenolic classes, extraction methods, purification techniques future compounds.

Язык: Английский

Процитировано

44

Seaweed-derived phenolic compounds as diverse bioactive molecules: A review on identification, application, extraction and purification strategies DOI
Abbas Sadeghi, Ali Rajabiyan,

Nafise Nabizade

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 266, С. 131147 - 131147

Опубликована: Март 26, 2024

Язык: Английский

Процитировано

33

Immunomodulation by xylan and carrageenan-type polysaccharides from red seaweeds: Anti-inflammatory, wound healing, cytoprotective, and anticoagulant activities DOI
Amal D. Premarathna, Tamer A. Ahmed, Vitālijs Rjabovs

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 260, С. 129433 - 129433

Опубликована: Янв. 17, 2024

Язык: Английский

Процитировано

26

Recent progress in natural seaweed pigments: Green extraction, health-promoting activities, techno-functional properties and role in intelligent food packaging DOI Creative Commons
Muhammad Faisal Manzoor, Muhammad Talha Afraz, Betül Bay Yılmaz

и другие.

Journal of Agriculture and Food Research, Год журнала: 2024, Номер 15, С. 100991 - 100991

Опубликована: Янв. 20, 2024

Edible seaweed is a worthwhile source of natural pigments (NPs) such as carotenoids, chlorophylls, and phycobiliproteins, these functional ingredients have been well-acknowledged due to their beneficial therapeutic properties. Green extraction techniques are the best option generate them more effectively by shorter times, lower operational temperatures, reduced solvent use, process automation aid in efficient compound retrieval. These NPs show valuable biological properties neuroprotective, anti-cancer, antioxidant, anti-inflammatory, anti-bacterial, anti-angiogenic, anti-obesity activities—the potential highlights applications food industries. frequently used colorants, providing nutritional value enhancing sensorial techno-functional final product. Also, use presently being expanded intelligent packaging observe freshness time-temperature indicator improve shelf life. Properly using foods could incline novel segment seaweed-based hybrid/composite health foods. This review critically analyzes recent advances from 2015 2023 NPs' green extraction, properties, ensuing items, role systems.

Язык: Английский

Процитировано

19

Marine macroalgae in a circular economy context: A comprehensive analysis focused on residual biomass DOI
Sara Pardilhó, João Cotas, Leonel Pereira

и другие.

Biotechnology Advances, Год журнала: 2022, Номер 60, С. 107987 - 107987

Опубликована: Май 21, 2022

Язык: Английский

Процитировано

62

Seaweed: Nutritional and gastronomic perspective. A review DOI Creative Commons
Marina Salido, Manu Soto, Sergio Seoane

и другие.

Algal Research, Год журнала: 2023, Номер 77, С. 103357 - 103357

Опубликована: Дек. 12, 2023

Seaweeds are organisms rich in many bioactive compounds such as proteins, minerals, vitamins, fibers, essential amino acids, pigments, and fatty which give them extraordinary antihypertensive, antidiabetic, antioxidant, anti-inflammatory, antitumoral, antiviral, antimicrobial properties. Seaweed could potentially contribute to future global security functional foods nutraceuticals be an important compound the pharmaceutical biotechnological industries drug development, among other uses. This review focuses on gastronomic point of view discusses compositional nutritional characteristics, topics related consumption, current application technologies, limitations challenges production, market developments this rising market.

Язык: Английский

Процитировано

30

Rehashing Our Insight of Seaweeds as a Potential Source of Foods, Nutraceuticals, and Pharmaceuticals DOI Creative Commons
Ravi S. Baghel,

Babita Choudhary,

Sonika Pandey

и другие.

Foods, Год журнала: 2023, Номер 12(19), С. 3642 - 3642

Опубликована: Окт. 1, 2023

In a few Southeast Asian nations, seaweeds have been staple of the cuisine since prehistoric times. Seaweeds are currently becoming more and popular around world due to their superior nutritional value medicinal properties. This is because rising seaweed production on global scale substantial research composition bioactivities over past 20 years. By reviewing several articles in literature, this review aimed provide comprehensive information about primary secondary metabolites various classes bioactive compounds, such as polysaccharides, polyphenols, proteins, essential fatty acids, along with bioactivities, single article. also highlights potential development nutraceuticals, particular focus ability enhance human health overall well-being. addition, we discuss challenges opportunities associated advancement pharmaceuticals nutraceuticals derived from seaweeds, well incorporation into different industrial sectors. Furthermore, find that many constituents found demonstrated terms therapeutic attributes, including antioxidative, anti-inflammatory, anticancer, other conclusion, seaweed-based compounds huge play an important role food, nutraceutical, pharmaceutical However, future should pay attention developing efficient techniques for extraction purification toxicity analysis, clinical efficacy, mode action, interactions regular diets.

Язык: Английский

Процитировано

24

Seaweed bioactives potential as nutraceuticals and functional ingredients: A review DOI Creative Commons
Joana Matos, Carlos Cardoso, Maria Luísa Serralheiro

и другие.

Journal of Food Composition and Analysis, Год журнала: 2024, Номер 133, С. 106453 - 106453

Опубликована: Июнь 22, 2024

Seaweeds are an important natural source of highly valuable bioactive compounds, namely vitamins, proteins, essential amino acids, omega-3 polyunsaturated fatty minerals and trace elements, carotenoids, polyphenols, enzymes carbohydrates. Their compounds have been associated to several biological activities, such as antioxidant, anticancer, antidiabetic, antimicrobial, anticoagulant, antiviral, anti-inflammatory, immunomodulatory, prebiotic, hypocholesterolemic. Due their richness in well-balanced composition, seaweeds become a promising innovative new functional ingredients, that can be used the development novel food products well nutraceuticals, thus, improving human health, well-being quality life, also contributing prevention treatment diseases. This review provides overview knowledge acquired last years about health benefits with molecules, consumption seaweeds-based foods nutraceuticals.

Язык: Английский

Процитировано

15

Seaweed: a sustainable solution for greening drug manufacturing in the pursuit of sustainable healthcare DOI Creative Commons
Leonel Pereira, João Cotas

Опубликована: Фев. 27, 2024

The environmental impact of drug manufacturing raises concerns about sustainability in healthcare. To address this, exploring alternative approaches to production is crucial. This review focuses on seaweed as a sustainable resource for greening processes. Seaweed offers advantages such renewability, abundance, and positive footprint. begins by providing an overview practices the challenges faced achieving sustainability. It then discusses resource, including cultivation techniques benefits. has various applications manufacturing, extracting purifying bioactive compounds with potential therapeutic properties. Seaweed’s role developing green technologies, seaweed-based excipients, biodegradable packaging materials, source energy processes, highlighted. economic implications incorporating solutions are discussed, emphasizing reduced carbon footprint cost-effectiveness. Regulatory industrial perspectives addressed, examining challenges, opportunities implementing manufacturing. Collaboration between academia, industry, regulatory bodies crucial successful integration. presents future directions opportunities, emerging trends innovations areas further research, policy development, industry engagement recommendations. Incorporating into facilitates reduction impact, promotes efficiency, contributes showcases means foster greener addressing concerns, promoting

Язык: Английский

Процитировано

14

Natural pigments: innovative extraction technologies and their potential application in health and food industries DOI Creative Commons
Ayu Masyita, Gemala Hardinasinta, Ayun Dwi Astuti

и другие.

Frontiers in Pharmacology, Год журнала: 2025, Номер 15

Опубликована: Янв. 8, 2025

Natural pigments, or natural colorants, are frequently utilized in the food industry due to their diverse functional and nutritional attributes. Beyond color properties, these pigments possess several biological activities, including antioxidant, anti-inflammatory, anticancer, antibacterial, neuroprotective effects, as well benefits for eye health. This review aims provide a timely overview of potential pharmaceutical, medical, industries. Special emphasis is placed on emerging technologies pigment extraction (thermal technologies, non-thermal supercritical fluid extraction), pharmacological application intelligent packaging colorants. show pharmaceutical prospects. For example, delphinidin (30 µM) significantly inhibited growth three cancer cell lines (B16-F10, EO771, RM1) by at least 90% after 48 h. Furthermore, an antioxidant agent, fucoxanthin highest concentration (50 μg/mL) increased ratio glutathione disulfide (p < 0.05). In industry, have been used improve value without altering sensory experience. Moreover, use pH-sensitive freshness indicators cutting-edge technological advancement. innovation could useful information consumers, increase shelf life, assist evaluating quality packaged observing variations over time. However, presents certain challenges, particularly regarding stability higher production costs compared synthetic pigments. situation underscores need further investigation into alternative sources improved stabilization methods. The instability emphasizes tendency degrade change when exposed various external conditions, light, oxygen, temperature fluctuations, pH levels, interactions with other substances matrix.

Язык: Английский

Процитировано

2